Lawsonia inermis

Common Names: henna

Ethnobotanical Studies

Studies

Bioactive nanofibrous mats constructs: Separate efficacy of Lawsonia inermis and Scrophularia striata extracts in PVA/alginate matrices for enhanced wound healing.

Akbarpour A et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.134545
PubMed:
39116967

Lawsone Unleashed: A Comprehensive Review on Chemistry, Biosynthesis, and Therapeutic Potentials.

Review
Nair AS et al (2024).
Drug Des Devel Ther.
DOI:
10.2147/DDDT.S463545
PubMed:
39081702

The effect of Henna (Lawsonia inermis) vaginal suppository combined with antibiotic therapy in the treatment of cervicitis: An RCT.

Summary

Research suggests henna oil may be an effective treatment for cervicitis, a common disease that can lead to inflammation, infertility, and cancer if left untreated.

Antimicrobial
Nabimeybodi N et al (2024).
Int J Reprod Biomed.
DOI:
10.18502/ijrm.v22i4.16388
PubMed:
39035632

Phytosynthesis of Eco-Friendly Silver Nanoparticles Using Lawsonia Innermis (L) and Their Biomedical Applications.

Senthilkumaran S et al (2024).
J Pharm Bioallied Sci.
DOI:
10.4103/jpbs.jpbs_561_23
PubMed:
38882846

Investigate the biological activities of Lawsonia inermis extract synthesized from TiO(2) doped graphene oxide nanoparticles.

Kaviyarasu K et al (2024).
Microsc Res Tech.
DOI:
10.1002/jemt.24625
PubMed:
38845108

Photostability and photodynamic antimicrobial profile of dye extracts from four (4) plants: prospects for eco-friendly low-cost food disinfection and topical biomedical applications.

Summary

Dye extracts from natural plants were tested for photostability and antimicrobial activity against bacteria and viruses. Lawsonia inermis showed the highest photostability and antibacterial activity, while Curcuma longa was most effective against viruses. This research may have applications in disinfection and sanitation practices.

Antimicrobial
Majiya H, Adamu A and Galstyan A (2024).
Photochem Photobiol Sci.
DOI:
10.1007/s43630-024-00585-8
PubMed:
38771468

Synthesis and characterization of iron oxide nanoparticles from Lawsonia inermis and its effect on the biodegradation of crude oil hydrocarbon.

Muthukumar B et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-61760-6
PubMed:
38760417

Enhanced bactericidal, antibiofilm and antioxidative response of Lawsonia inermis leaf extract synthesized ZnO NPs loaded with commercial antibiotic.

Summary

Li-ZnO NPs have strong antibacterial and radical scavenging effects. Conjugating with ciprofloxacin enhances antibacterial efficacy against drug-resistant bacteria, offering a sustainable treatment option. This research could lead to new, effective, and affordable antibiotics to combat global antibiotic resistance.

Antimicrobial
Malaikozhundan B et al (2024).
Bioprocess Biosyst Eng.
DOI:
10.1007/s00449-024-03000-9
PubMed:
38607416

Lawsonia inermis-organically modified chitosan intercalated bentonite clay: A multifunctional nanotheranostic system for controlled drug delivery, sensing and cellular imaging.

Sirajunnisa P, Sreelakshmi S and Sailaja GS (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.130209
PubMed:
38365155

Back to nature: henna extracts from nanotech to environmental biotechnology - a review.

Review
Abd-El-Haleem DAM et al (2023).
BioTechnologia (Pozn).
DOI:
10.5114/bta.2023.132776
PubMed:
38213476

Functionalization of bamboo fibers with lawsone dye (Lawsonia inermis) to produce bioinspired hybrid color composite with antibacterial activity.

Szadkowski B et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.129178
PubMed:
38184044

Identification of apigenin-4'-glucoside as bacterial DNA gyrase inhibitor by QSAR modeling, molecular docking, DFT, molecular dynamics, and in vitro confirmation studies.

Genetics
Harini M et al (2024).
J Mol Model.
DOI:
10.1007/s00894-023-05813-z
PubMed:
38170229

Correction: Therapeutic potential of Lawsonia inermis Linn: a comprehensive overview.

Batiha GE et al (2024).
Naunyn Schmiedebergs Arch Pharmacol.
DOI:
10.1007/s00210-023-02932-5
PubMed:
38165427

Unearthing the inhibitory potential of phytochemicals from Lawsonia inermis L. and some drugs against dengue virus protein NS1: an in silico approach.

Das D et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2298730
PubMed:
38157248

The Comparison of the Anti-inflammatory Efficacy of Phytochemical Extracts in Punica granatum and Lawsonia inermis Among Patients Diagnosed With Chronic Periodontitis.

ImmunologyPhytochemistry
Takkella BK 3rd et al (2023).
Cureus.
DOI:
10.7759/cureus.47557
PubMed:
38021636

Therapeutic potential of Lawsonia inermis Linn: a comprehensive overview.

Review
Batiha GE et al (2023).
Naunyn Schmiedebergs Arch Pharmacol.
DOI:
10.1007/s00210-023-02735-8
PubMed:
38010396

New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines.

Summary

Researchers found a new compound () in henna, along with other known compounds. They also discovered new ellagitannins that are cytotoxic to oral squamous cell carcinoma cells. Henna has potential for anti-oral cancer treatment and further study is encouraged.

Cancer
Orabi MAA et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12111951
PubMed:
38001804

Evaluation of antibacterial efficacy of Lawsonia inermis Linn (henna) on periodontal pathogens using agar well diffusion and broth microdilution methods: An in-vitro study.

Güler Ş et al (2023).
Biomedicine (Taipei).
DOI:
10.37796/2211-8039.1411
PubMed:
37937057

In Vitro Antioxidant and Inhibitory Study of Picrorhiza kurroa (Kutki), Syzygium aromaticum (Loung), Lawsonia inermis (Henna), Rheum emodi (Revand Chini), Curcuma longa (Haldi) Against Lipid Per-Oxidation in Mice Brain and Liver.

Summary

This study evaluated the antioxidant and protective properties of certain medicinal plants against oxidative stress in the brain and liver. , , and showed strong effects and could potentially help manage or prevent degenerative diseases.

ImmunologyNeuroscience
Hassan F et al (2023).
Dose Response.
DOI:
10.1177/15593258231210431
PubMed:
37900620

Evaluation of anti-inflammatory and immunomodulatory potential of Lawsone (2-hydroxy-1,4-naphthoquinone) using pre-clinical rodent model of rheumatoid arthritis.

ArthritisImmunology
Sattar S et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1279215
PubMed:
37900171

Production of bioactive and aroma volatile compounds of Lawsonia inermis L. cultivated under different growth conditions.

Pistelli L et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2272279
PubMed:
37865973

Antibacterial Effects of Methanol Henna (Lawsone inermis) Leaf Extracts against Two Food Borne Infection Causing Pathogens: Gram-Positive Staphylococcus aureus and Gram Negative Klebsiella pneumoniae.

Zannat KE et al (2023).
Mymensingh Med J.
PubMed:
37777894

Isolation of phenolic compound from Lawsonia inermis and its prediction as anti-diabetic agent using molecular docking and molecular dynamic simulation.

Summary

Scientists isolated and characterized a phenolic compound from the henna plant that has the potential as an anti-diabetic agent. The compound showed a high affinity for specific enzymes and was well-predicted in terms of skin permeability and distribution. Potential for new diabetes medication.

DiabetesPhytochemistry
Musfiroh I et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2262595
PubMed:
37776010

Anti-Yeasts, Antioxidant and Healing Properties of Henna Pre-Treated by Moist Heat and Molecular Docking of Its Major Constituents, Chlorogenic and Ellagic Acids, with Candida albicans and Geotrichum candidum Proteins.

Immunology
Alsalamah SA et al (2023).
Life (Basel).
DOI:
10.3390/life13091839
PubMed:
37763243

Growth inhibitory effect of selected quinones from Indian medicinal plants against Theileria annulata.

Kiriyanthan RM et al (2023).
Exp Parasitol.
DOI:
10.1016/j.exppara.2023.108622
PubMed:
37758051

In Vivo Wound-Healing Effect of Chemical and Green Synthesized Chitosan Nanoparticles Using Lawsonia inermis Ethanolic Extract.

Metwally AA et al (2023).
Microsc Microanal.
DOI:
10.1093/micmic/ozad026
PubMed:
37749685

Promising role of Lawsonia inermis L. leaves extract and its nano-formulation as double treatment against aflatoxin toxicity in ulcerated-rats: Application in milk beverage.

Mohammed DM et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e19290
PubMed:
37681189

Antibacterial Effects of Chloroform Henna (Lawsonia inermis) Leaf Extracts against Two Nosocomial Infection Causing Pathogens: Gram-positive Staphylococcus aureus and Gram-negative Klebsiella pneumoniae: A Comparative Study.

Zannat KE et al (2023).
Mymensingh Med J.
PubMed:
37391949

Nanostructured CuO Thin-Film-Based Conductometric Sensors for Real-Time Tracking of Sweat Loss.

Aydın R et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c02232
PubMed:
37305318

Electrophoretic Deposition, Microstructure, and Selected Properties of Poly(lactic-co-glycolic) Acid-Based Antibacterial Coatings on Mg Substrate.

Manzur J et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c01384
PubMed:
37251160

Greener design and characterization of biochar/Fe(3)O(4)@SiO(2)-Ag magnetic nanocomposite as efficient catalyst for synthesis of bioactive benzylpyrazolyl coumarin derivatives.

Dharmendra D et al (2023).
RSC Adv.
DOI:
10.1039/d3ra00869j
PubMed:
37188256

The effect of a topical formulation from Lawsonia inermis L. (henna) on pain intensity in patients with chronic sciatica: A randomized double-blind clinical trial.

Summary

Researchers studied the effects of henna oil on chronic sciatica. Henna oil is often recommended in traditional medicine for pain relief. Understanding its effectiveness can help with managing sciatica and improving patient care.

Pain
Lavari N et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116519
PubMed:
37105368

Antibacterial Activity of Green Synthesized Silver Nanoparticles Using Lawsonia inermis Against Common Pathogens from Urinary Tract Infection.

Said A et al (2023).
Appl Biochem Biotechnol.
DOI:
10.1007/s12010-023-04482-1
PubMed:
37099124

Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre-clinical studies published from 2010 to 2020.

Summary

Researchers conducted a systematic review of scientific articles published between 2010 and 2020 that evaluated the anxiolytic, sedative, and/or hypnotic effects of flower extracts in pre-clinical animal models. They found that some flower extracts have an anxiolytic effect comparable to diazepam, but their therapeutic utility in anxiety disorders needs more investigation. The study compiled the characteristics of anxiety studies in animal models, evaluated locomotor activity, and the hypnotic effect of the extracts. The study revealed that matricaria chamomilla had a sedative effect, and 23 other flower plants had anxiolytic effects. However, more reliable behavioral tests and better experimental designs are needed to obtain more conclusive evidence with clinical significance.

Review Neuroscience
Meneses C et al (2023).
Phytother Res.
DOI:
10.1002/ptr.7830
PubMed:
37039741

Antibacterial Effects of Methanolic Leaf Extracts of Henna (Lawsonia inermis) Against Two Most Common Pathogenic Organisms: Gram Positive Staphylococcus aureus and Gram-Negative Escherichia coli.

Zannat KE et al (2023).
Mymensingh Med J.
PubMed:
37002737

Lawsonia inermis flower aqueous extract expressed better anti-alpha-glucosidase and anti-acetylcholinesterase activity and their molecular dynamics.

Neuroscience
Shahanaj I et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2179546
PubMed:
36905654

Lawsonia inermis-loaded poly (L-lactide-co-D, L-lactide) nanofibers for healing acceleration of burn wounds.

Bayati S et al (2023).
J Biomater Sci Polym Ed.
DOI:
10.1080/09205063.2022.2155779
PubMed:
36469758

Biosynthesis of silver nanoparticles using Lawsonia inermis and their biomedical application.

Alhomaidi E et al (2022).
IET Nanobiotechnol.
DOI:
10.1049/nbt2.12096
PubMed:
36039655

Assessment of the antiulcer properties of Lawsonia inermis L. leaves and its nano-formulation against prolonged effect of acute ulcer in rats.

Mohammed DM et al (2022).
Toxicol Rep.
DOI:
10.1016/j.toxrep.2022.03.010
PubMed:
35284236

Pain-relieving effects of Lawsonia inermis on neuropathic pain induced by chronic constriction injury.

Pain
Rakhshandeh H et al (2021).
Metab Brain Dis.
DOI:
10.1007/s11011-021-00773-w
PubMed:
34169409

Wound Healing Effect of Lawsonia inermis.

Rekik DM et al (2019).
Skin Pharmacol Physiol.
DOI:
10.1159/000501730
PubMed:
31466077

Antimalarial actions of Lawsonia inermis, Tithonia diversifolia and Chromolaena odorata in combination.

Afolayan FID et al (2016).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2016.06.045
PubMed:
27321410

Lawsonia inermis - an alternative treatment for hyperthyroidism?

Zumrutdal E et al (2014).
Bratisl Lek Listy.
PubMed:
24601697