Lepidium sativum

Common Names: gardencress pepperweed

Ethnobotanical Studies

Studies

Phytolacca americana extract as a quality-enhancing factor for biodegradable double-layered films based on furcellaran and gelatin - Property assessment.

Jasińska JM et al (2024).
Int J Biol Macromol.
PubMed:
39214197

Effects of mulberry leaf enrichment with Lepidium sativum L. seed powder suspension on the economic parameters of Bombyx mori L.

Alfazairy AA et al (2024).
Sci Rep.
PubMed:
39179694

Treatment of D-galactose-induced rat polycystic ovarian condition using Lepidium sativum and secondary antibodies.

Summary

Scientists studied the causes and treatment of PCOS, a common hormonal disorder in women. Understanding this can lead to improved management and potential breakthroughs in treatment.

Alharbi Y, Alkhail AA and Zaki AK (2024).
J Adv Vet Anim Res.
PubMed:
39101077

Anti-Oxidative and Anti-Apoptotic Oligosaccharides from Pichia pastoris-Fermented Cress Polysaccharides Ameliorate Chromium-Induced Liver Toxicity.

Khan IU et al (2024).
Pharmaceuticals (Basel).
PubMed:
39065806

Novel garden cress-fish gelatin based ointment: Improvement of skin wound healing in rats through modulation of anti-inflammatory and antioxidant states.

Salem A et al (2024).
Heliyon.
PubMed:
39022005

Beneficial role of Coronatine on the morphological and physiological responses of Cress Plants (Lepidium sativum) exposed to Silver Nanoparticle.

Shahraki SH et al (2024).
Bot Stud.
PubMed:
38985236

Comparative Study of Lepidium Sativum Orally Administered Seeds, Hydrogel and Atorvastatin on Obesity of Rats Fed on a High Fat Diet.

Summary

Researchers are exploring natural products as alternatives to statins for managing hyperlipidemia and obesity. This could lead to safer and more effective treatment options for those suffering from obesity-related complications.

Aldosari BN et al (2024).
Drug Dev Ind Pharm.
PubMed:
38963406

The Seed Germination Test as a Valuable Tool for the Short-Term Phytotoxicity Screening of Water-Soluble Polyamidoamines.

Ranucci E et al (2024).
Polymers (Basel).
PubMed:
38932092

Garden cress seeds: a review on nutritional composition, therapeutic potential, and industrial utilization.

Review
Tufail T et al (2024).
Food Sci Nutr.
PubMed:
38873486

Indigenous herbal medicine use and its associated factors among pregnant women attending antenatal care at public health facilities in Dire Dawa, Ethiopia: a cross-sectional study.

Mohammed A et al (2024).
BMJ Open.
PubMed:
38830740

Mitigating Effect of Lepidium sativum Seeds Oil on Ovarian Oxidative Stress, DNA Abnormality and Hormonal Disturbances Induced by Acrylamide in Rats.

Summary

L. sativum seeds oil contains antioxidants that protect rats' ovaries from acrylamide damage, reducing levels of harmful compounds and improving reproductive health. This may offer a new treatment for female infertility.

Aboul Naser AF, El-Feky AM and Hamed MA (2024).
Chem Biodivers.
PubMed:
38743868

Physicochemical and ecotoxicological approaches for Moknine Continental Sebkha in Tunisia.

Summary

Scientists studied water quality in Moknine, Tunisia due to heavy contamination from industrial and domestic sources. High levels of pollutants and toxicity were found, likely due to mercury, phthalates, and other chemicals, posing risks to ecosystems and human health.

Belaid A et al (2024).
J Water Health.
PubMed:
38678430

Ethnobotanical survey on herbal remedies for the management of type 2 diabetes in the Casablanca-Settat region, Morocco.

Summary

Study investigates the use of medicinal plants in traditional medicine in Casablanca-Settat region for managing type 2 diabetes. Essential for addressing public health challenge in Morocco.

Arraji M et al (2024).
BMC Complement Med Ther.
PubMed:
38622669

The Antimicrobial Effects of Myrosinase Hydrolysis Products Derived from Glucosinolates Isolated from Lepidium draba.

Summary

Scientists isolated and purified glucosinolates from hoary cress and myrosinase from garden cress. They found differences in hydrolysis rates and conversion to anticancer isothiocyanates. This research could lead to the development of dietary supplements with potential antimicrobial properties.

Polozsányi Z et al (2024).
Plants (Basel).
PubMed:
38611524

Sodium alginate films incorporated with Lepidium sativum (Garden cress) extract as a novel method to enhancement the oxidative stability of edible oil.

Alshehri AA et al (2024).
Int J Biol Macromol.
PubMed:
38508545

Allelopathy and Identification of Five Allelochemicals in the Leaves of the Aromatic Medicinal Tree Aegle marmelos (L.) Correa.

Moh SM et al (2024).
Plants (Basel).
PubMed:
38498556

Novel drug therapy of acute hepatic failure induced in rats by a combination of tadalafil and Lepidium sativum.

Sabra MS et al (2024).
BMC Complement Med Ther.
PubMed:
38413963

To spread or not to spread? Assessing the suitability of sewage sludge and other biogenic wastes for agriculture reuse.

Bertanza G et al (2024).
MethodsX.
PubMed:
38379723

Ecotoxicological assessment of biomass-derived furan platform chemicals using aquatic and terrestrial bioassays.

Parmaki S et al (2024).
Environ Sci Process Impacts.
PubMed:
38372577

Uptake, translocation, and metabolization of amitriptyline, lidocaine, orphenadrine, and tramadol by cress and pea.

Detzlhofer A et al (2024).
Environ Sci Pollut Res Int.
PubMed:
38363510

Spent coffee grounds as a suitable alternative to standard soil in ecotoxicological tests.

Mendes LA and Domínguez J (2024).
Environ Sci Pollut Res Int.
PubMed:
38326678

Effects of composts obtained from hazelnut wastes on the cultivation of pepper (Capsicum annuum) seedlings.

Ceylan F et al (2024).
Sci Rep.
PubMed:
38321176

In-vivo Immunomodulatory Activities of Essential Oils of Artemisia abyssinica and Lepidium sativum in Mice.

Ayenew KD et al (2024).
Immunotargets Ther.
PubMed:
38288461

Germination Behavior and Geographical Information System-Based Phenotyping of Root Hairs to Evaluate the Effects of Different Sources of Black Soldier Fly (Hermetia illucens) Larval Frass on Herbaceous Crops.

Labella R et al (2024).
Plants (Basel).
PubMed:
38256783

Neuroprotective Effect of Solid Lipid Nanoparticles Loaded with Lepidium sativum (L.) Seed Bioactive Components Enhance Bioavailability and Wnt/β-Catenin/Camk-II Signaling Cascade in SH-SY5Y Neuroblastoma Cells.

Summary

Solid lipid nanoparticles (SLNps) loaded with seed extract show potential as a therapeutic approach for Alzheimer's disease by increasing bioavailability and efficacy in preventing oxidative stress-induced neurodegeneration. LS-SLNps exhibit neuroprotective effects, boost cell proliferation, and stimulate nerve cell growth factor expression.

Al-Saran N et al (2024).
Nanomaterials (Basel).
PubMed:
38251163

In vitro chronic phytotoxicity of heavy metals and metalloids to Lepidium sativum (garden cress).

Bożym M and Rybak J (2024).
Ecotoxicology.
PubMed:
38227083

Development of Oral Formulation of Lepidium Seeds Significantly Decreases the High Blood Glucose Levels in Diabetic Rats; In Vitro Formulation and In Vivo Antidiabetic Performance.

Summary

Researchers investigated the natural molecules in Garden Cress seeds that can reduce blood glucose levels. This could be significant in finding potential treatments for disorders related to high blood glucose.

Aldosari BN et al (2023).
Drug Dev Ind Pharm.
PubMed:
38156891

Allelochemical root-growth inhibitors in low-molecular-weight cress-seed exudate.

Khan MI et al (2023).
Ann Bot.
PubMed:
38141653

Ecotoxicological assessment of waste-derived organic fertilizers and long-term monitoring of fertilized soils using a multi-matrix and multi-species approach.

Carraturo F et al (2023).
Sci Total Environ.
PubMed:
38097080

A review on the fate of micro and nano plastics (MNPs) and their implication in regulating nutrient cycling in constructed wetland systems.

Gupta N, Parsai T and Kulkarni HV (2023).
J Environ Manage.
PubMed:
38016236

Investigating the Chemical Composition of Lepidium sativum Seeds and Their Ability to Safeguard against Monosodium Glutamate-Induced Hepatic Dysfunction.

El-Gendy MS et al (2023).
Foods.
PubMed:
38002187

The exogenous application of naringenin and rosmarinic acid modulates functional traits in Lepidium sativum.

Salehi H et al (2023).
J Sci Food Agric.
PubMed:
37994181

Highly sensitive analysis of photoregulation and dynamic distribution of phytohormones based on nanoconfined liquid phase nanoextraction.

Wang L et al (2023).
Anal Chim Acta.
PubMed:
37977798

Utilization of crop wild relatives for biotic and abiotic stress management in Indian mustard [Brassica juncea (L.) Czern. & Coss.].

Review
Verma S et al (2023).
Front Plant Sci.
PubMed:
37954999

Uptake and metabolization of four sartan drugs by eight different plants: Targeted and untargeted analyses by HPLC-drift-tube-ion-mobility quadrupole time-of-flight mass spectrometry.

Zellner L et al (2023).
Electrophoresis.
PubMed:
37946621

Research Update on the Therapeutic Potential of Garden Cress (Lepidium sativum Linn.) with Threatened Status.

Gupta S and Gupta R (2023).
Curr Drug Res Rev.
PubMed:
37929722

Garden Cress Seed Oil Abrogates Testicular Oxidative Injury and NF-kB-Mediated Inflammation in Diabetic Mice.

Summary

This study found that a biologically active seed oil (LSO) improved testicular dysfunction in diabetic mice by increasing testosterone levels and reducing oxidative damage and inflammation. LSO may be a potential therapeutic option for male reproductive dysfunction in diabetes.

Abu-Khudir R et al (2023).
Int J Mol Sci.
PubMed:
37895159

Investigating the Metabolism of Plants Germinated in Heavy Water, D(2)O, and H(2)(18)O-Enriched Media Using High-Resolution Mass Spectrometry.

Osipenko S et al (2023).
Int J Mol Sci.
PubMed:
37895078

Obtaining New Candidate Peptides for Biological Anticancer Drugs from Enzymatic Hydrolysis of Human and Bovine Hemoglobin.

Summary

Hydrolyzing hemoglobin produces bioactive peptides with anticancer properties. Certain bovine hemoglobin peptides are more active than human peptides, suggesting potential for anticancer drug development using hemoglobin.

Outman A et al (2023).
Int J Mol Sci.
PubMed:
37895063

Impact of Enterococcus italicus ONU547 on the growth and acclimatization of micropropagated Rubus fruticosus L. and Paulownia tomentosa Steud. plants to ex vitro conditions.

Tytarenko N et al (2023).
BioTechnologia (Pozn).
PubMed:
37850117

Design of a novel fluorescent metal-organic framework (UiO-66-NG) for the detection of boric acid in aqueous medium and bioimaging in a living plant system.

Yildirim A et al (2023).
Talanta.
PubMed:
37832455

Phage Therapy Against Pathogenic Escherichia coli (O104:H4, O157:H7, and O26) Strains in Irrigation Water During Garden Cress (Lepidium sativum Linn.) Vegetation.

Iskender I and Soyer Y (2023).
Foodborne Pathog Dis.
PubMed:
37801662

Lepidium sativum Seed Extract-Mediated Synthesis of Zinc Oxide Nanoparticles: Structural, Morphological, Optical, Hemolysis, and Antibacterial Studies.

Alnehia A et al (2023).
Bioinorg Chem Appl.
PubMed:
37780971

Chemical Composition of Essential Oils from Eight Tunisian Eucalyptus Species and Their Antifungal and Herbicidal Activities.

Summary

Scientists analyzed the essential oils (EOs) from eight plant species in Tunisia to determine their chemical composition. The EOs were found to have antifungal and herbicidal activities, making them potentially useful as biopesticides and bioherbicides in agriculture.

Ayed A et al (2023).
Plants (Basel).
PubMed:
37687315

Extraction, Characterization, and Evaluation of Lepidium sativum Linn. Mucilage as a Mucoadhesive Polymer.

Embafrash Berhe H et al (2023).
Adv Pharmacol Pharm Sci.
PubMed:
37609005

Lepidium sativum alleviates diabetic nephropathy in a rat model by attenuating glucose levels, oxidative stress, and inflammation with concomitant suppression of TGF-β1.

Summary

Whole-plant extract treated diabetic nephropathy in rats by reducing fasting glucose and cholesterol levels, attenuating kidney damage, and decreasing inflammatory markers. Promising therapy for diabetic nephropathy.

Alsuliam SM et al (2023).
Saudi J Biol Sci.
PubMed:
37576066

Extractability and phytotoxicity of heavy metals and essential elements from plastics in soil solutions and root exudates.

Jędruchniewicz K et al (2023).
Sci Total Environ.
PubMed:
37558061

Fabrication of bioactive nanocomposites from chitosan, cress mucilage, and selenium nanoparticles with powerful antibacterial and anticancerous actions.

El-Sherbiny MM et al (2023).
Front Microbiol.
PubMed:
37547689

Characterization of free oligosaccharides from garden cress seed aqueous exudate using PGC LC-MS/MS and NMR spectroscopy.

Lijina P, Manjunatha JR and Gnanesh Kumar BS (2023).
Carbohydr Res.
PubMed:
37541111

Investigation on Chemical Composition, Antioxidant, Antifungal and Herbicidal Activities of Volatile Constituents from Deverra tortuosa (Desf.).

Summary

The study analyzed essential oils (EOs) from and found they have antioxidant, antifungal, and herbicidal properties. They could be useful for pest management and sustainable agriculture.

Khammassi M et al (2023).
Plants (Basel).
PubMed:
37447117

Colletotriauxins A-D, New Plant Growth Inhibitors from the Phytopathogenic Fungus Colletotrichum gloeosporioides.

Zhou J, Wei H and Li SM (2023).
J Agric Food Chem.
PubMed:
37434536

Evaluation of toxicity and genotoxicity of concrete cast with steel slags using higher terrestrial plants.

Alias C et al (2023).
Environ Toxicol Chem.
PubMed:
37401854

The effect of biotransformation of sewage sludge- and willow-derived biochars by horseradish peroxidase on total and freely dissolved polycyclic aromatic hydrocarbon content.

Siatecka A and Oleszczuk P (2023).
Sci Total Environ.
PubMed:
37391151

Phytochemical Extracts of Dittrichia viscosa (L.) Greuter from Agroecological Systems: Seed Antigerminative Properties and Effectiveness in Counteracting Alternaria Leaf Spot Disease on Baby-Leaf Spinach.

Pane C et al (2023).
Biology (Basel).
PubMed:
37372075

Defective TiO(2) Nanotube Arrays for Efficient Photoelectrochemical Degradation of Organic Pollutants.

Machreki M et al (2023).
ACS Omega.
PubMed:
37360499

Ecotoxicity Evaluation of Industrial Waste and Construction Materials: Comparison Between Leachates from Granular Steel Slags and Steel Slags-Containing Concrete Through a Plant-Based Approach.

Alias C et al (2023).
Bull Environ Contam Toxicol.
PubMed:
37341817

Antineoplastic drugs in urban wastewater: Occurrence, nanofiltration treatment and toxicity screening.

Gouveia TIA et al (2023).
Environ Pollut.
PubMed:
37290632

Enhanced selectivity and recovery of phosphate and nitrate ions onto coffee ground waste biochars via co-precipitation of Mg/Al layered double hydroxides: A potential slow-release fertilizer.

Shin J et al (2023).
Environ Res.
PubMed:
37257744

Allelopathic Potential of Lantana camara L. Leaf Extracts and Soils Invaded by It on the Growth Performance of Lepidium sativum L.

Gebreyohannes L et al (2023).
ScientificWorldJournal.
PubMed:
37214643

An integrated characterisation of incineration bottom ashes towards sustainable application: Physicochemical, ecotoxicological, and mechanical properties.

Bandarra BS et al (2023).
J Hazard Mater.
PubMed:
37210879

In vitro anti-plasmodial activity of three selected medicinal plants that are used in local traditional medicine in Amhara region of Ethiopia.

Ejigu YW and Endalifer BL (2023).
BMC Pharmacol Toxicol.
PubMed:
37170269

Targeting apoptotic anticancer response with natural glucosinolates from cell suspension culture of Lepidium sativum.

Ibrahim MM, Mounier MM and Bekheet SA (2023).
J Genet Eng Biotechnol.
PubMed:
37127764

Garden Cress (Lepidium sativum) Seeds Ameliorated Aluminum-Induced Alzheimer Disease in Rats Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Effects.

Balgoon MJ et al (2023).
Neuropsychiatr Dis Treat.
PubMed:
37077707

Isolation and Identification of Plant-Growth Inhibitory Constituents from Polygonum chinense Linn and Evaluation of Their Bioherbicidal Potential.

Lun TL et al (2023).
Plants (Basel).
PubMed:
37050203

Allelopathic Activity of Canadian Goldenrod (Solidago canadensis L.) Extracts on Seed Germination and Growth of Lettuce (Lactuca sativa L.) and Garden Pepper Cress (Lepidium sativum L.).

Judžentienė A et al (2023).
Plants (Basel).
PubMed:
37050047

Simultaneous Heavy Metal-Polycyclic Aromatic Hydrocarbon Removal by Native Tunisian Fungal Species.

Hkiri N et al (2023).
J Fungi (Basel).
PubMed:
36983467

Toxicity evaluation of the contaminated area of Crotone from biological indicators: a multispecies approach.

Mastroberardino A et al (2023).
Environ Monit Assess.
PubMed:
36928511

Bioactivity of brassica seed meals and its compounds as ecofriendly larvicides against mosquitoes.

Flor-Weiler LB et al (2023).
Sci Rep.
PubMed:
36894606

In silico molecular modeling of cold pressed garden cress (Lepidium sativum L.) seed oil toward the binding pocket of antimicrobial resistance Staphylococcus aureus DNA-gyrase complexes.

Almuhayawi MS et al (2023).
Eur Rev Med Pharmacol Sci.
PubMed:
36876662

Nanosatellite Payload for Research on Seed Germination in a 3D Printed Micropot.

Kawa B et al (2023).
Sensors (Basel).
PubMed:
36850572

Spontaneous Officinal Plants in the Cilento, Vallo di Diano and Alburni National Park: Tradition, Protection, Enhancement, and Recovery.

De Falco E et al (2023).
Plants (Basel).
PubMed:
36771560

Sulfonic Cryogels as Innovative Materials for Biotechnological Applications: Synthesis, Modification, and Biological Activity.

Laishevkina S et al (2023).
Int J Mol Sci.
PubMed:
36769272

Synthesis of active packaging films from Lepidium sativum gum/polyvinyl alcohol composites and their application in preserving cheddar cheese.

Rehim MA, Zahran HA and Al-Moghazy M (2023).
Sci Rep.
PubMed:
36717620

Effect of Innovative Bio-Based Plastics on Early Growth of Higher Plants.

Liwarska-Bizukojc E et al (2023).
Polymers (Basel).
PubMed:
36679317

Allelopathic Substances of Osmanthus spp. for Developing Sustainable Agriculture.

Kato-Noguchi H et al (2023).
Plants (Basel).
PubMed:
36679091

Changes in Pharmacokinetics and Pharmacodynamics of Losartan in Experimental Diseased Rats Treated with Curcuma longa and Lepidium sativum.

Ahad A et al (2022).
Pharmaceuticals (Basel).
PubMed:
36678530

Removal of Zinc from Concentrated Galvanic Wastewater by Sodium Trithiocarbonate: Process Optimization and Toxicity Assessment.

Thomas M et al (2023).
Molecules.
PubMed:
36677604

Garden cress gum and maltodextrin as microencapsulation coats for entrapment of garden cress phenolic-rich extract: improved thermal stability, storage stability, antioxidant and antibacterial activities.

Abdel-Aty AM, Barakat AZ and Mohamed SA (2022).
Food Sci Biotechnol.
PubMed:
36606085

Nematicidal activity of sweet annie and garden cress nano-formulations and their impact on the vegetative growth and fruit quality of tomato plants.

Mohammad AA et al (2022).
Sci Rep.
PubMed:
36566273

Evidence for Health-Promoting Properties of Lepidium sativum L.: An Updated Comprehensive Review.

Hekmatshoar Y, Özkan T and Rahbar Saadat Y (2022).
Turk J Pharm Sci.
PubMed:
36544402

Effect of graphene oxide on the uptake, translocation and toxicity of metal mixture to Lepidium sativum L. plants: Mitigation of metal phytotoxicity due to nanosorption.

Kazlauskas M et al (2023).
Chemosphere.
PubMed:
36403815

Swine slaughterhouse biowaste: an environmental sustainability assessment of composting, amended soil quality, and phytotoxicity.

Batista-Barwinski MJ et al (2024).
Environ Technol.
PubMed:
36355390

A comparative study of the chloroplast genomes of five Lepidium species with high medicinal value.

Zhou Q et al (2023).
Funct Plant Biol.
PubMed:
36043226

Solid Lipid Nanoparticles of Lepidium Sativum L Seed Extract: Formulation, Optimization and In vitro Cytotoxicity Studies.

Ahmad A et al (2022).
Drug Res (Stuttg).
PubMed:
35504297

Nutraceutical Profiling, Bioactive Composition, and Biological Applications of Lepidium sativum L.

Review
Painuli S et al (2022).
Oxid Med Cell Longev.
PubMed:
35096265

Herb-drug interaction: pharmacokinetics and pharmacodynamics of anti-hypertensive drug amlodipine besylate in presence of Lepidium sativum and Curcuma longa.

Alam MA et al (2022).
Xenobiotica.
PubMed:
34958609

Lepidium sativum Secondary Metabolites (Essential Oils): In Vitro and In Silico Studies on Human Hepatocellular Carcinoma Cell Lines.

Nazir S et al (2021).
Plants (Basel).
PubMed:
34579396

Lepidium sativum as candidate against excitotoxicity in retinal ganglion cells.

Al-Dbass A et al (2021).
Transl Neurosci.
PubMed:
34141454

A Panoramic Review on Lepidium sativum L. Bioactives as Prospective Therapeutics.

Review
Ahmad A et al (2021).
Drug Res (Stuttg).
PubMed:
33378774

Lepidium sativum: Bone healer in traditional medicine, an experimental validation study in rats.

Dixit Jr Iii V et al (2020).
J Family Med Prim Care.
PubMed:
32318426

Lepidine B from Lepidium sativum Seeds as Multi-Functional Anti- Alzheimer's Disease Agent: In Vitro and In Silico Studies.

Summary

In this study, researchers tested the anticholinesterase effects of L. sativum and other plants. They specifically looked at the ability of two compounds, Lepidine B & E, to inhibit various enzymes involved in nervous system signaling. The researchers were able to determine the specific interactions between the compounds and the enzymes. These findings suggest potential therapeutic applications for the compounds in neurological disorders.

Talia S et al (2021).
Curr Comput Aided Drug Des.
PubMed:
32116197

Lepidium sativum Linn.: a current addition to the family of mucilage and its applications.

Review
Prajapati VD et al (2014).
Int J Biol Macromol.
PubMed:
24418343