Common Names: greater butter-and-eggs, yellow toadflax, flaxweed, Jacob's ladder, ramsted, wild snapdragon, butter and eggs
PR-DPR, produced by C9-ALS, leads to motor neuron degeneration. PLG, an antioxidant from a medicinal herb, reduces ROS and apoptosis caused by PR-DPR by activating the SIRT3/OPA1 axis. PLG shows potential for C9-ALS drug development.
Researchers analyzed the chemicals found in Linaria vulgaris and found similar patterns to other Linaria plants, with the presence of several compounds including a new one called 4-carboxy-boonein. The study's findings could have implications for the use of these plants in traditional medicine.