Lobelia chinensis

Common Names: Chinese lobelia

Ethnobotanical Studies

Studies

Lobelia chinensis Lour inhibits the progression of hepatocellular carcinoma via the regulation of the PTEN/AKT signaling pathway in vivo and in vitro.

Luo J et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116886
PubMed:
37429502

In silico evaluation of flavonoids as potential inhibitors of SARS-CoV-2 main nonstructural proteins (Nsps)-amentoflavone as a multitarget candidate.

Summary

Researchers explored the potential of flavonoids as COVID-19 treatment options. Through virtual screening, they identified amentoflavone, found in plants like Ginkgo biloba, as a potential multitarget inhibitor against essential non-structural proteins of the virus. Molecular docking calculations and structural analysis support this potential. Amentoflavone is widely available, low-cost, has no side effects, and a long history of use. Future experiments are needed to validate its effectiveness as an inhibitor against SARS-CoV-2.

COVID-19Phytochemistry
Portilla-Martínez A et al (2022).
J Mol Model.
DOI:
10.1007/s00894-022-05391-6
PubMed:
36445575

Lobelia chinensis Extract and Its Active Compound, Diosmetin, Improve Atopic Dermatitis by Reinforcing Skin Barrier Function through SPINK5/LEKTI Regulation.

Dermatology
Park NJ et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms23158687
PubMed:
35955819

Chemical structure elucidation of an inulin-type fructan isolated from Lobelia chinensis lour with anti-obesity activity on diet-induced mice.

Obesity
Zhang X et al (2020).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2020.116357
PubMed:
32475601

The anti-tubercular activity of Melia azedarach L. and Lobelia chinensis Lour. and their potential as effective anti-Mycobacterium tuberculosis candidate agents.

Choi WH and Lee IA (2016).
Asian Pac J Trop Biomed.
DOI:
10.1016/j.apjtb.2016.08.007
PubMed:
32289023

Isolation and bioactive evaluation of flavonoid glycosides from Lobelia chinensis Lour using two-dimensional liquid chromatography combined with label-free cell phenotypic assays.

Phytochemistry
Wang J et al (2019).
J Chromatogr A.
DOI:
10.1016/j.chroma.2019.04.073
PubMed:
31101464

Chemical Profiling of Lobelia chinensis with High-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry (HPLC/Q-TOF MS) Reveals Absence of Lobeline in the Herb.

Phytochemistry
Wang H et al (2018).
Molecules.
DOI:
10.3390/molecules23123258
PubMed:
30544710

Preliminary assessment of two non-destructive instrumental techniques for quality evaluation of Lobelia chinensis Lour.

Chen HP et al (2016).
J Pharm Anal.
DOI:
10.1016/j.jpha.2015.06.001
PubMed:
29403983

Study of Commercially Available Lobelia chinensis Products Using Bar-HRM Technology.

Sun W et al (2017).
Front Plant Sci.
DOI:
10.3389/fpls.2017.00351
PubMed:
28360920

Evaluating the cytotoxic effects of the water extracts of four anticancer herbs against human malignant melanoma cells.

Cancer
Ling B et al (2016).
Drug Des Devel Ther.
PubMed:
27843296

A study on the effect of aqueous extract of Lobelia chinensis on colon precancerous lesions in rats.

Cancer
Han SR et al (2013).
Afr J Tradit Complement Altern Med.
PubMed:
24311860