Common Names: Indian-tobacco
Researchers used high-performance liquid chromatography and mass spectrometry to identify and analyze the alkaloid profile of Lobelia inflata L, a plant with potential pharmacotherapy for methamphetamine abuse. They identified 52 alkaloids in the plant, some of which were previously unknown, including several propyl homologue lobelia alkaloids and five hydroxypiperidine derivatives. They also found a new natural product, a 3-hydroxy-3-phenylpropanoic acid ester of hydroxyallosedamine ring-substituted. The study demonstrates the usefulness of this method for routine screening of plants for bioactive constituents, quality control, alkaloid production studies, breeding, and chemotaxonomy.