Lycium chinense

Common Names: Chinese desert-thorn

Ethnobotanical Studies

Studies

Matrix-assisted laser desorption/ionization mass spectrometry for the rapid and high throughput analysis of betaine and trigonelline in Lycium chinense Mill. and trigonelline in coffee.

Zhou P et al (2024).
Food Chem X.
DOI:
10.1016/j.fochx.2024.101703
PubMed:
39211765

Study on Betaine and Growth Characteristics of Lycium chinense Mill. in Different Cultivation Environments in South Korea.

Cho H et al (2024).
Plants (Basel).
DOI:
10.3390/plants13162316
PubMed:
39204752

Lycium chinense Mill Induces Anti-Obesity and Anti-Diabetic Effects In Vitro and In Vivo.

Summary

Mill extract (LCM) increases GLP-1 secretion, reduces lipid accumulation, promotes weight loss, improves glucose tolerance, and exhibits hepatoprotective properties in obesity and diabetes. Promising natural treatment option.

DiabetesObesity
Jee W et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25168572
PubMed:
39201257

The Medicinal Species of the Lycium Genus (Goji Berries) in East Asia: A Review of Its Effect on Cell Signal Transduction Pathways.

Review
Jiang C et al (2024).
Plants (Basel).
DOI:
10.3390/plants13111531
PubMed:
38891336

Carotenoid biosynthesis genes LcLCYB, LcLCYE, and LcBCH from wolfberry confer increased carotenoid content and improved salt tolerance in tobacco.

Genetics
Li C et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-60848-3
PubMed:
38719951

Concentrations, Sources and Health Risk Assessment of Polycyclic Aromatic Hydrocarbons in Chinese Herbal Medicines.

Cao D et al (2024).
Molecules.
DOI:
10.3390/molecules29050972
PubMed:
38474484

Insights into How Plant-Derived Extracts and Compounds Can Help in the Prevention and Treatment of Keloid Disease: Established and Emerging Therapeutic Targets.

Review
Boo YC et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25021235
PubMed:
38279232

Trichoderma asperellum boosts nitrogen accumulation and photosynthetic capacity of wolfberry (Lycium chinense) under saline soil stress.

Yan K et al (2023).
Tree Physiol.
DOI:
10.1093/treephys/tpad148
PubMed:
38079510

Transcriptional deciphering of the metabolic pathways associated with the bioactive ingredients of wolfberry species with different quality characteristics.

Liu X et al (2023).
BMC Genomics.
DOI:
10.1186/s12864-023-09755-x
PubMed:
37919673

Partial substitution of chemical fertilizer by Trichoderma biofertilizer improved nitrogen use efficiency in wolfberry (Lycium chinense) in coastal saline land.

Yan K et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1225028
PubMed:
37877079

Kukoamine A protects mice against osteoarthritis by inhibiting chondrocyte inflammation and ferroptosis via SIRT1/GPX4 signaling pathway.

Summary

In this study, researchers investigated the effects of a compound called KuKA on osteoarthritis. They found that KuKA has anti-inflammatory properties and can help regulate the development of osteoarthritis. This could lead to potential new treatments for the disease.

Immunology
Sun J et al (2023).
Life Sci.
DOI:
10.1016/j.lfs.2023.122117
PubMed:
37741321

Lycium chinense Miller fruit extract lowers liver enzyme levels in subjects with mild hepatic dysfunction: a randomized, double-blind, placebo-controlled clinical trial.

Oh MR et al (2023).
Eur J Nutr.
DOI:
10.1007/s00394-022-03075-8
PubMed:
36629892

Anti-Apoptotic and Anti-Inflammatory Effects of an Ethanolic Extract of Lycium chinense Root against Particulate Matter 10-Induced Cell Death and Inflammation in RBL-2H3 Basophil Cells and BALB/c Mice.

Immunology
Lee J et al (2022).
Plants (Basel).
DOI:
10.3390/plants11192485
PubMed:
36235350

[Effects of Trichoderma on nitrogen absorption and use efficiency in Lycium chinense roots under saline stress].

Mei HM et al (2022).
Ying Yong Sheng Tai Xue Bao.
DOI:
10.13287/j.1001-9332.202209.015
PubMed:
36131671

The Effects of Lycium chinense, Cuscuta chinensis, Senna tora, Ophiopogon japonicus, and Dendrobium nobile Decoction on a Dry Eye Mouse Model.

Yang CC et al (2022).
Medicina (Kaunas).
DOI:
10.3390/medicina58081134
PubMed:
36013601

Ameliorative potentials of the ethanolic extract from Lycium chinense leaf extract against diabetic cardiomyopathy. Insight into oxido-inflammatory and apoptosis modulation.

CardiologyImmunology
Wen C et al (2022).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2022.113583
PubMed:
35994819

Modulating effects of oral administration of Lycii Fructus extracts on UVB-induced skin erythema: A Randomized, placebo-controlled study.

Tsunenaga M et al (2022).
Biomed Rep.
DOI:
10.3892/br.2022.1545
PubMed:
35719836

Network Pharmacology with Experimental Investigation of the Mechanisms of Rhizoma Polygonati against Prostate Cancer with Additional Herbzymatic Activity.

Cancer
Kazybay B et al (2022).
ACS Omega.
DOI:
10.1021/acsomega.1c03018
PubMed:
35531567

Betaine, a component of Lycium chinense, enhances muscular endurance of mice and myogenesis of myoblasts.

Genetics
Lee SS et al (2021).
Food Sci Nutr.
DOI:
10.1002/fsn3.2466
PubMed:
34532017

Qisheng Wan formula ameliorates cognitive impairment of Alzheimer's disease rat via inflammation inhibition and intestinal microbiota regulation.

Summary

Qisheng Wan formula (QWF), a traditional Chinese medicine, has been used to treat forgetfulness and dementia due to its ability to improve cognitive function. QWF consists of seven herbal drugs, including Poria cocos, Cinnamomum cassia, and Panax ginseng. Its efficacy has been documented in the book Sheng Ji Zong Lu, written in 1117. While further research is needed to validate QWF's effectiveness, its long-standing use in traditional medicine highlights the potential benefits of natural remedies.

ImmunologyNeuroscience
Xiong W et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2021.114598
PubMed:
34492320

Discrimination of Lycium chinense and L. barbarum Based on Metabolite Analysis and Hepatoprotective Activity.

Ryu MJ et al (2020).
Molecules.
DOI:
10.3390/molecules25245835
PubMed:
33321994

Lycium chinense leaves extract ameliorates diabetic nephropathy by suppressing hyperglycemia mediated renal oxidative stress and inflammation.

DiabetesImmunology
Olatunji OJ, Chen H and Zhou Y (2018).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2018.03.037
PubMed:
29710532

Acid sphingomyelinase as target of Lycium Chinense: promising new action for cell health.

Ceccarini MR et al (2016).
Lipids Health Dis.
PubMed:
27756324

Natural products of relevance in the prevention and supportive treatment of depression.

Muszyńska B et al (2015).
Psychiatr Pol.
DOI:
10.12740/PP/29367
PubMed:
26276913

Discrimination of Lycium chinense and Lycium barbarum by taste pattern and betaine analysis.

Lee HW et al (2014).
Int J Clin Exp Med.
PubMed:
25232386