Malva sylvestris

Common Names: garden mallow, high mallow

Ethnobotanical Studies

Güce district, north-eastern Turkey

Uses: cough, stomach disorder, cancer, constipation, dyspepsia, stomach ache, sore throat, oedema, cholesterol, anemia, diuretic, abscess, analgesic, bronchitis, expectorant, hair loss, wounds

DOI:: 10.1016/j.pld.2022.03.005
PubMed:: 36540712

Marmilla Subregion, Sardinia, Italy

Uses: Against boils, chilblains, Bronchial renal and intestinal anti-inflammatory, suppurative lesions, fistulas, Against boils, chilblains, suppurative lesions, fistulas, and hemorrhoids, Processes inflammatory in the throat

DOI:: 10.3390/plants11223165
PubMed:: 36432894

Shouf Biosphere Reserve, Lebanon

Uses: Cough, Fever, Catarrh, Laxative, Expectorant, Emollient, Diarrhea Skin and Mucous membranes inflammations, Ophthalmic ailments Sedative for sleep problems, digestive troubles

DOI:: 10.1186/s13002-022-00568-y
PubMed:: 36572929

Central Europe

DOI:: 10.3390/plants12010135
PubMed:: 36616265

Viesca and Parras Coahuila, northeast Mexico

Uses: Skin, Eye, Ear, Nose, and Oropharynx Diseases

DOI:: 10.1016/j.jsps.2022.11.003
PubMed:: 36685306

Clinical Trials

The Effect of Malva Sylvestris Cream on Episiotomy Pain and Healing: A Randomized Controlled Clinical Trial.

Study in Iran examined the impact of Malva Sylvestris cream on pain and healing for women undergoing episiotomy during childbirth. Results could improve postpartum care.

Mohaghegh Z et al (2022).; Int J Community Based Nurs Midwifery.
DOI:: 10.30476/IJCBNM.2022.95772.2082
PubMed:: 36274662

Efficacy and safety of the syrup "KalobaTUSS®" as a treatment for cough in children: a randomized, double blind, placebo-controlled clinical trial.

Carnevali I et al (2021).; BMC Pediatr.
DOI:: 10.1186/s12887-020-02490-2
PubMed:: 33430841

Efficacy of the Malva sylvestris L. flowers aqueous extract for functional constipation: A placebo-controlled trial.

Elsagh M et al (2015).; Complement Ther Clin Pract.
DOI:: 10.1016/j.ctcp.2015.02.003
PubMed:: 25801702

Studies

Comparison of the anti-plaque and anti-gingivitis efficacy of Chlorhexidine and Malva mouthwashes: randomized crossover clinical trial.

Zuttion GS et al (2024).; J Dent.
DOI:: 10.1016/j.jdent.2024.105313
PubMed:: 39173823

Malvidin From Malva sylvestris L. Ameliorates Allergic Responses in Ovalbumin-Induced Allergic Rhinitis Mouse Model via the STAT6/GATA3 Pathway.

Immunology

Yirui L et al (2024).; Am J Rhinol Allergy.
DOI:: 10.1177/19458924241272944
PubMed:: 39135425

Comprehensive assessment of clean-up strategies for optimizing an analytical multi-method to determine pesticides and mycotoxins in Brazilian medicinal herbs using QuEChERS-LC-TQ-MS/MS.

Zorzella Fontana ME et al (2024).; Anal Methods.
DOI:: 10.1039/d4ay00599f
PubMed:: 38990094

Effects of natural products-based dentifrices on acrylic resin for denture bases: A simulated period of 4 years.

Costa MS et al (2024).; Am J Dent.
PubMed:: 38899991

Protective Effects of the Aqueous Extract of Malva sylvestris Plant against the Lethality and Histopathological Damage in Experimental Envenoming of Hemiscorpius lepturus Venom in Balb/c Mice.

Ahmadi SM et al (2024).; Curr Pharm Des.
DOI:: 10.2174/0113816128296935240502070245
PubMed:: 38757320

The rhizosphere of a drought-tolerant plant species in Morocco: A refuge of high microbial diversity with no taxon preference.

Legeay J et al (2024).; Environ Microbiol Rep.
DOI:: 10.1111/1758-2229.13254
PubMed:: 38725134

Effectiveness of a natural coagulant based on common mallow (Malva sylvestris) in urban wastewater treatment.

Aguilera Flores MM et al (2024).; Environ Technol.
DOI:: 10.1080/09593330.2024.2346861
PubMed:: 38686920

Electrospun fiber mats based on chitosan-carrageenan containing Malva sylvestris anthocyanins: Physic-mechanical, thermal, and barrier properties along with application as intelligent food packaging materials.

Shavisi N et al (2024).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2024.131077
PubMed:: 38531525

Poly(vinyl alcohol) /Alginate nanofibrous mats containing Malva Sylvestris extract: Synthesis, characterization, in vitro and in vivo assessments for burn wound applications.

Akbarpour A et al (2024).; Int J Pharm.
DOI:: 10.1016/j.ijpharm.2024.123928
PubMed:: 38401874

10.

Potential benefits of Malva sylvestris in dry-eye disease pathology in vitro based on antioxidant, wound-healing and anti-inflammatory properties.

Immunology

Areesanan A et al (2023).; Biomed Pharmacother.
DOI:: 10.1016/j.biopha.2023.115782
PubMed:: 37924786

11.

Land use influences the nutrient concentration and composition of pollen and nectar rewards of wildflowers in human-dominated landscapes.

Pioltelli E et al (2023).; Sci Total Environ.
DOI:: 10.1016/j.scitotenv.2023.168130
PubMed:: 37907100

12.

Phytochemistry and Pharmacological Activity of Malva sylvestris L: A Detailed Insight.

Summary

Mallow (Malva sylvestris) is a plant with diverse pharmacological activities. Its phytochemicals have antioxidant and anticancer properties. It contains essential minerals, has nutritional value, and can be used in medicinal herbs, cosmetics, and antibacterial treatments. It also has anti-inflammatory, analgesic, and wound healing properties.

Phytochemistry

Paul ZA et al (2023).; Comb Chem High Throughput Screen.
DOI:: 10.2174/0113862073269336231009110313
PubMed:: 37855358

13.

New Insights on Primary and Secondary Metabolite Contents of Seven Italian Wild Food Plants with Medicinal Applications: A Comparative Study.

Monari S et al (2023).; Plants (Basel).
DOI:: 10.3390/plants12183180
PubMed:: 37765345

14.

Profile and potential bioactivity of the miRNome and metabolome expressed in Malva sylvestris L. leaf and flower.

Villani V et al (2023).; BMC Plant Biol.
DOI:: 10.1186/s12870-023-04434-1
PubMed:: 37726667

15.

Near-Zero Temperatures Arrest Movement of the Diaheliotropic Malva sylvestris.

Arvaniti E, Levizou E and Kyparissis A (2023).; Plants (Basel).
DOI:: 10.3390/plants12132484
PubMed:: 37447045

16.

An edible coating utilizing Malva sylvestris seed polysaccharide mucilage and postbiotic from Saccharomyces cerevisiae var. boulardii for the preservation of lamb meat.

Abbasi A et al (2023).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2023.125660
PubMed:: 37399877

17.

Malva sylvestris, a new host of Puccinia modiolae in Korea.

Ryu H et al (2023).; Plant Dis.
DOI:: 10.1094/PDIS-03-23-0442-PDN
PubMed:: 37246338

18.

The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.

van der Schoot A et al (2023).; Neurogastroenterol Motil.
DOI:: 10.1111/nmo.14613
PubMed:: 37243443

19.

The Lubricating Effect of Eye Drops Containing Hyaluronic Acid and Mallow Extract in Patients with Dry Eye Disease-A Pilot Study.

Basile AA et al (2023).; Medicina (Kaunas).
DOI:: 10.3390/medicina59050958
PubMed:: 37241190

20.

Development and characterization of a new active and intelligent packaging system based on soluble soybean polysaccharide-Malva sylvestris extract.

Jafarian M, Taghinia P and Sedaghati S (2023).; J Food Sci Technol.
DOI:: 10.1007/s13197-023-05727-x
PubMed:: 37206422

21.

Modulation of the bacterial virulence and resistance by well-known European medicinal herbs.

Křížkovská B et al (2023).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2023.116484
PubMed:: 37044231

22.

Radioprotective effect of Malva sylvestris L. against radiation-induced liver, kidney and intestine damages in rat: A histopathological study.

Azmoonfar R et al (2023).; Biochem Biophys Rep.
DOI:: 10.1016/j.bbrep.2023.101455
PubMed:: 36969320

23.

Effects of glycerol and sorbitol on a novel biodegradable edible film based on Malva sylvestris flower gum.

Jaderi Z et al (2022).; Food Sci Nutr.
DOI:: 10.1002/fsn3.3134
PubMed:: 36789080

24.

Field evaluation of industrial non-food crops for phytomanaging a metal-contaminated dredged sediment.

Perlein A et al (2023).; Environ Sci Pollut Res Int.
DOI:: 10.1007/s11356-022-24964-9
PubMed:: 36701059

25.

Development and Application of Edible Coatings with Malva sylvestris L. Extract to Extend Shelf-Life of Small Loaf.

Alexieva I et al (2022).; Foods.
DOI:: 10.3390/foods11233831
PubMed:: 36496640

26.

A Quantitative Study on the Ethnobotanical Knowledge about Wild Edible Plants among the Population of Messiwa.

Ethnobotany

Ghanimi R et al (2022).; Ethiop J Health Sci.
DOI:: 10.4314/ejhs.v32i6.22
PubMed:: 36475263

27.

The phytochemical profiling, pharmacological activities, and safety of malva sylvestris: a review.

Review Phytochemistry

Batiha GE et al (2023).; Naunyn Schmiedebergs Arch Pharmacol.
DOI:: 10.1007/s00210-022-02329-w
PubMed:: 36418467

28.

Optimization of process parameters for fabrication of electrospun nanofibers containing neomycin sulfate and Malva sylvestris extract for a better diabetic wound healing.

Diabetes

Monirul Islam M et al (2022).; Drug Deliv.
DOI:: 10.1080/10717544.2022.2144963
PubMed:: 36404771

29.

In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity.

Genetics

Mazzari ALDA et al (2022).; Front Pharmacol.
DOI:: 10.3389/fphar.2022.826395
PubMed:: 36278236

30.

Synthesis and Characterization of Copper-Nanoflowers with the Utilization of Medicinal Plant Extracts for Enhanced Various Enzyme Inhibitory Activities.

Koca-Caliskan U et al (2022).; Chem Biodivers.
DOI:: 10.1002/cbdv.202200476
PubMed:: 36149402

31.

Walking around the Autonomous Province of Trento (Italy): An Ethnobotanical Investigation.

Ethnobotany

Cavalloro V et al (2022).; Plants (Basel).
DOI:: 10.3390/plants11172246
PubMed:: 36079629

32.

High throughput analytical approach based on μQuEChERS combined with UHPLC-PDA for analysis of bioactive secondary metabolites in edible flowers.

Izcara S et al (2022).; Food Chem.
DOI:: 10.1016/j.foodchem.2022.133371
PubMed:: 35661599

33.

A Review on Health Benefits of Malva sylvestris L. Nutritional Compounds for Metabolites, Antioxidants, and Anti-Inflammatory, Anticancer, and Antimicrobial Applications.

Review Antimicrobial Immunology

Mousavi SM et al (2021).; Evid Based Complement Alternat Med.
DOI:: 10.1155/2021/5548404
PubMed:: 34434245

34.

Malva sylvestris extract alleviates the astrogliosis and inflammatory stress in LPS-induced depression mice.

Immunology

Wu Y et al (2019).; J Neuroimmunol.
DOI:: 10.1016/j.jneuroim.2019.577029
PubMed:: 31487612

35.

Malva sylvestris derivatives as inhibitors of HIV-1 BaL infection.

Benso B et al (2021).; Nat Prod Res.
DOI:: 10.1080/14786419.2019.1619720
PubMed:: 31429300

36.

Cardioprotective effect of Malva sylvestris L. in myocardial ischemic/reprefused rats.

Cardiology

Zuo H et al (2017).; Biomed Pharmacother.
DOI:: 10.1016/j.biopha.2017.08.111
PubMed:: 28886527

37.

Malva sylvestris extract protects upon lithium carbonate-induced kidney damages in male rat.

Ben Saad A et al (2016).; Biomed Pharmacother.
DOI:: 10.1016/j.biopha.2016.10.026
PubMed:: 27780138

38.

Effect of Malva sylvestris cream on burn injury and wounds in rats.

Nasiri E et al (2015).; Avicenna J Phytomed.
PubMed:: 26909337

39.

Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells. An In Vitro Infection Model.

Immunology

Benso B et al (2015).; PLoS One.
DOI:: 10.1371/journal.pone.0140331
PubMed:: 26479870