Marsdenia tenacissima

Ethnobotanical Studies

Studies

Antihepatoma activity of Marsdenia tenacissima polysaccharide-decorated selenium nanoparticles by regulating the Bax/Bcl-2/caspases and p21/Akt/cyclin A2 signaling pathways.

Zhang S et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.134981
PubMed:
39182863

P-glycoprotein-mediated herb-drug interaction evaluation between Tenacissoside G and paclitaxel.

Hu J et al (2024).
Biomed Chromatogr.
DOI:
10.1002/bmc.5984
PubMed:
39152775

Low-concentration exogenous 3-indoleacetic acid improves fruit-setting rate of Marsdenia tenacissima by inhibiting the expression of embryo abortion-related genes.

Genetics
Zhang H et al (2024).
Gene.
DOI:
10.1016/j.gene.2023.147930
PubMed:
38381505

Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway.

Dong J et al (2024).
Eur J Pharmacol.
DOI:
10.1016/j.ejphar.2024.176401
PubMed:
38331340

The Protective Effect of Marsdenia tenacissima against Cisplatin-Induced Nephrotoxicity Mediated by Inhibiting Oxidative Stress, Inflammation, and Apoptosis.

Summary

This study shows that the traditional Chinese medicine (TCM) MT can enhance the anti-tumor effect of cisplatin (Cis) while reducing its toxic side effects, specifically nephrotoxicity. MT improves renal function, decreases inflammation, and regulates apoptosis through the Nrf2 and NF-κB pathways. Use MT as an adjuvant to mitigate Cis-induced nephrotoxicity.

Immunology
Zhang Z et al (2023).
Molecules.
DOI:
10.3390/molecules28227582
PubMed:
38005304

Combinatorics-based chemical characterization and bioactivity comparison of different parts of traditional Chinese medicinal plants through LC-Q-TOF-MS/MS, multivariate statistical analysis and bioassay: Marsdenia tenacissima as an example.

Chen YH et al (2023).
J Chromatogr B Analyt Technol Biomed Life Sci.
DOI:
10.1016/j.jchromb.2023.123850
PubMed:
37598457

Corrigendum to "Multi-omics joint analysis reveals the mechanism of action of the traditional Chinese medicine Marsdenia tenacissima (Roxb.) Moon in the treatment of hepatocellular carcinoma" [J. Ethnopharmacol. 293 (2022) 115285].

Li S et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116998
PubMed:
37550138

Marsdenia tenacissima extract induces endoplasmic reticulum stress-associated immunogenic cell death in non-small cell lung cancer cells through targeting AXL.

Cancer
Yuan Y et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116620
PubMed:
37207882

Allelopathic Potential of Marsdenia tenacissima (Roxb.) Moon against Four Test Plants and the Biological Activity of Its Allelopathic Novel Compound, 8-Dehydroxy-11β-O-Acetyl-12β-O-Tigloyl-17β-Marsdenin.

Moh SM et al (2023).
Plants (Basel).
DOI:
10.3390/plants12081663
PubMed:
37111887

Marsdenia tenacissima extract prevents the malignant progression of glioma through upregulating lncRNA MEG3 and SFRP1-dependent inhibition of Wnt/β-catenin pathway.

Chen L, Gong X and Huang M (2023).
CNS Neurosci Ther.
DOI:
10.1111/cns.14100
PubMed:
36756719

Optimization of Cordyceps sinensis fermentation Marsdenia tenacissima process and the differences of metabolites before and after fermentation.

Wang S et al (2022).
Heliyon.
DOI:
10.1016/j.heliyon.2022.e12586
PubMed:
36636205

Marsdenia tenacissima genome reveals calcium adaptation and tenacissoside biosynthesis.

Genetics
Zhou Y et al (2023).
Plant J.
DOI:
10.1111/tpj.16081
PubMed:
36575579

Nontargeted metabolomics study and pharmacodynamic evaluation of bidirectional fermentation for Ganoderma lucidum with Marsdenia tenacissima.

Li R et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.1012063
PubMed:
36386222

Extract of Marsdenia tenacissima (Roxb.) Moon [Apocynaceae] Suppresses Hepatocellular Carcinoma by Inhibiting Angiogenesis.

Pan Y et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.900128
PubMed:
35847002

Marsdenia tenacissima (Roxb.) Moon injection exerts a potential anti-tumor effect in prostate cancer through inhibiting ErbB2-GSK3β-HIF1α signaling axis.

Cancer
Chen X et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115381
PubMed:
35595220

Distributions of eight bioactive components in rat tissues administered Marsdenia tenacissima extract orally detected through UPLC-MS/MS.

Li S et al (2021).
Biomed Chromatogr.
DOI:
10.1002/bmc.5034
PubMed:
33226666

Marsdenia tenacissima extract dilated small mesenteric arteries via stimulating endothelial nitric oxide synthase and inhibiting calcium influx.

Hao H et al (2019).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2019.111847
PubMed:
30946966