Melilotus officinalis

Common Names: cornilla real, field melilot, ribbed melilot, yellow sweetclover

Ethnobotanical Studies

Studies

Newly Developed Semi-Solid Formulations Containing Mellilotus officinalis Extract: Characterization, Assessment of Stability, Safety, and Anti-Inflammatory Activity.

Immunology
Bradic J et al (2024).
Pharmaceutics.
DOI:
10.3390/pharmaceutics16081003
PubMed:
39204348

Dicoumarol attenuates NLRP3 inflammasome activation to inhibit inflammation and fibrosis in knee osteoarthritis.

Immunology
Ge W et al (2024).
Mol Med Rep.
DOI:
10.3892/mmr.2024.13224
PubMed:
38639180

Comparative analysis of codon usage patterns in the chloroplast genomes of nine forage legumes.

Xiao M et al (2024).
Physiol Mol Biol Plants.
DOI:
10.1007/s12298-024-01421-0
PubMed:
38623162

Reduction of Post-Surgical Facial Edema Following Bromelain and Coumarin Intake in Traumatology: A Prospective Study with 100 Patients.

Consorti G et al (2024).
J Clin Med.
DOI:
10.3390/jcm13040922
PubMed:
38398236

Living mulch enhances soil enzyme activities, nitrogen pools and water retention in giant reed (Arundo donax L.) plantations.

Elhawat N et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-51491-z
PubMed:
38242963

Cultivation of Melilotus officinalis as a source of bioactive compounds in association with soil recovery practices.

Nogues I et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1218594
PubMed:
37771488

Effect of Trichoderma viride on insoluble phosphorus absorption ability and growth of Melilotus officinalis.

Song M et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-39501-y
PubMed:
37524898

Acknowledging the use of botanicals to treat diabetic foot ulcer during the 21(st) century: A systematic review.

Summary

DFU is a common and serious problem for diabetics. Treating it is difficult, particularly for people with weak immune systems.

Diabetes
Narzary I et al (2023).
World J Clin Cases.
DOI:
10.12998/wjcc.v11.i17.4035
PubMed:
37388781

Non-destructive distinction of single seed for Medicago sativa and Melilotus officinalis by capillary electrophoresis with laser-induced fluorescence detection.

Xia J et al (2023).
J Chromatogr A.
DOI:
10.1016/j.chroma.2023.464116
PubMed:
37290349

Chromosome-scale assembly and analysis of Melilotus officinalis genome for SSR development and nodulation genes analysis.

Genetics
He Q et al (2023).
Plant Genome.
DOI:
10.1002/tpg2.20345
PubMed:
37259688

Effect of yellow sweetclover (Melilotus officinalis) hay compared with Lucerne (Medicago sativa) hay on carcass characteristics and meat quality of male goat kids.

Mouad LB et al (2022).
J Adv Vet Anim Res.
DOI:
10.5455/javar.2022.i631
PubMed:
36714513

Designing nanofibrous poly(ε-caprolactone)/hydroxypropyl cellulose/zinc oxide/Melilotus Officinalis wound dressings using response surface methodology.

Shahrousvand M and Golshan Ebrahimi N (2022).
Int J Pharm.
DOI:
10.1016/j.ijpharm.2022.122338
PubMed:
36309291

Anaerobic Fungi Isolated From Bactrian Camel Rumen Contents Have Strong Lignocellulosic Bioconversion Potential.

Xue Y et al (2022).
Front Microbiol.
DOI:
10.3389/fmicb.2022.888964
PubMed:
35928163

Viability of Wildflower Seeds After Mesophilic Anaerobic Digestion in Lab-Scale Biogas Reactors.

Hahn J et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.942346
PubMed:
35909787

Reference nodule transcriptomes for Melilotus officinalis and Medicago sativa cv. Algonquin.

Genetics
Huang R, Snedden WA and diCenzo GC (2022).
Plant Direct.
DOI:
10.1002/pld3.408
PubMed:
35774624

Exploring the Potential Mechanisms of Melilotus officinalis (L.) Pall. in Chronic Muscle Repair Patterns Using Single Cell Receptor-Ligand Marker Analysis and Molecular Dynamics Simulations.

Chen Y et al (2022).
Dis Markers.
DOI:
10.1155/2022/9082576
PubMed:
35692879

Three-layered PCL-collagen nanofibers containing melilotus officinalis extract for diabetic ulcer healing in a rat model.

Diabetes
Derakhshan MA et al (2022).
J Diabetes Metab Disord.
DOI:
10.1007/s40200-022-00976-7
PubMed:
35673445

Healing Influence of Melilotus Officinalis Herbal Extract on Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice.

Hassani M et al (2020).
Iran J Pharm Res.
DOI:
10.22037/ijpr.2020.113808.14505
PubMed:
33841545

Analyzing the Carotenoid Composition of Melilot (Melilotus officinalis (L.) Pall.) Extracts and the Effects of Isolated (All-E)-lutein-5,6-epoxide on Primary Sensory Neurons and Macrophages.

Summary

Scientists have investigated the carotenoid content of Meliloti herba, a medicinal plant with anti-inflammatory effects. Using high performance liquid chromatography (HPLC) and column liquid chromatography (CLC), they isolated and identified the main carotenoid as (all-)-lutein 5,6-epoxide and tested its effects on primary sensory neurons and macrophages involved in inflammation. Results showed that lutein 5,6-epoxide reduced the activation of primary sensory neurons and decreased the release of IL-1β from macrophages. This suggests that lutein 5,6-epoxide could be used as an analgesic and anti-inflammatory treatment.

ImmunologyNeuroscience
Horváth G et al (2021).
Molecules.
DOI:
10.3390/molecules26020503
PubMed:
33477841

Chemical Constituents and Antioxidant, Anti-Inflammatory and Anti-Tumor Activities of Melilotus officinalis (Linn.) Pall.

Immunology
Liu YT et al (2018).
Molecules.
DOI:
10.3390/molecules23020271
PubMed:
29382154