Mentha pulegium

Common Names: pennyroyal

Ethnobotanical Studies

Güce district, north-eastern Turkey

Uses: common cold, influenza, sore throat, dyspepsia, nausea, diarrheal, tonsillitis, cough, dyspnea, asthma

DOI:: 10.1016/j.pld.2022.03.005
PubMed:: 36540712

Marmilla Subregion, Sardinia, Italy

Uses: Aromatic and refreshing, bechico, bronchodilator, against digestive system disorders

DOI:: 10.3390/plants11223165
PubMed:: 36432894

Shouf Biosphere Reserve, Lebanon

Uses: Spasms, Fever, Cholagogue, Common colds, Infections of throat, catarrh, lungs, Bronchitis Carminative, Expectorant, Anticatarrhal, Disinfectant, Abdominal ailments

DOI:: 10.1186/s13002-022-00568-y
PubMed:: 36572929

Central Europe

DOI:: 10.3390/plants12010135
PubMed:: 36616265

Viesca and Parras Coahuila, northeast Mexico

Uses: Gastro-intestinal system diseases, SND

DOI:: 10.1016/j.jsps.2022.11.003
PubMed:: 36685306

Ecuador

Uses: To treat stomach colic, indigestion, and the cold.

DOI:: 10.3390/plants11121590
PubMed:: 35736741

Studies

Enhancing growth and bioactive metabolites characteristics in Mentha pulegium L. via silicon nanoparticles during in vitro drought stress.

El-Naggar HM and Osman AR (2024).; BMC Plant Biol.
DOI:: 10.1186/s12870-024-05313-z
PubMed:: 38987699

Unlocking the combined action of Mentha pulegium L. essential oil and Thym honey: In vitro pharmacological activities, molecular docking, and in vivo anti-inflammatory effect.

Immunology Phytochemistry

Assaggaf H et al (2024).; Heliyon.
DOI:: 10.1016/j.heliyon.2024.e31922
PubMed:: 38947443

Green synthesis of silver doped zinc oxide/magnesium oxide nanocomposite for waste water treatment and examination of their cytotoxicity properties.

Shekofteh Narm T et al (2024).; Heliyon.
DOI:: 10.1016/j.heliyon.2024.e30374
PubMed:: 38726184

Assessment and Optimization of the Insecticidal Properties of γ-Al(2)O(3) Nanoparticles Derived from Mentha pulegium By-Products to Xylosandrus crassiusculus (Carob Beetle).

Mohamed Abdoul-Latif F et al (2024).; Molecules.
DOI:: 10.3390/molecules29061205
PubMed:: 38542842

Antibacterial Effect of Eight Essential Oils against Bacteria Implicated in Bovine Mastitis and Characterization of Primary Action Mode of Thymus capitatus Essential Oil.

Phytochemistry

Aouadhi C et al (2024).; Antibiotics (Basel).
DOI:: 10.3390/antibiotics13030237
PubMed:: 38534672

In vitro ruminal fermentation, core nutrient, fatty acids and mineral matter of pennyroyal (Mentha pulegium L.) herbage at different phenological stages.

Kara K et al (2024).; Vet Med Sci.
DOI:: 10.1002/vms3.1397
PubMed:: 38450960

Radioprotective effect of nanoniosome loaded by Mentha Pulegium essential oil on human peripheral blood mononuclear cells exposed to ionizing radiation.

Phytochemistry

Hamzian N et al (2024).; Drug Dev Ind Pharm.
DOI:: 10.1080/03639045.2024.2317297
PubMed:: 38334353

Anti-inflammatory effects of Mentha pulegium L. extract on human peripheral blood mononuclear cells are mediated by TLR-4 and NF-κB suppression.

Immunology

Mohammadi F et al (2024).; Heliyon.
DOI:: 10.1016/j.heliyon.2024.e24040
PubMed:: 38234883

Medicinal herbs consumption in relation to cardiometabolic indices and coronary artery stenosis in participants undergoing coronary angiography: A cross-sectional study.

Arabi V et al (2024).; Phytother Res.
DOI:: 10.1002/ptr.8113
PubMed:: 38233343

10.

Impact of Climate Change on the Chemical Compositions and Antioxidant Activity of Mentha pulegium L.

Immunology

Laftouhi A et al (2023).; ACS Omega.
DOI:: 10.1021/acsomega.3c05564
PubMed:: 38107916

11.

Different cultivation systems and foliar application of calcium nanoparticles affect the growth and physiological characteristics of pennyroyal (Mentha pulegium L.).

Roosta HR, Samadi A and Bikdeloo M (2023).; Sci Rep.
DOI:: 10.1038/s41598-023-47855-6
PubMed:: 37989836

12.

Screening of 20 species from Lamiaceae family based on phytochemical analysis, antioxidant activity and HPLC profiling.

Immunology Phytochemistry

Moshari-Nasirkandi A et al (2023).; Sci Rep.
DOI:: 10.1038/s41598-023-44337-7
PubMed:: 37813985

13.

Optimisation of three essential oils against Salmonella spp. and Escherichia coli by mixture design.

Kachkoul R et al (2023).; Chem Biodivers.
DOI:: 10.1002/cbdv.202301221
PubMed:: 37783668

14.

Lower dose of plant substance more effective in repelling Rhyzopertha dominica F . (Coleoptera, Bostrichidae) and Sitophilus granarius L. (Coleoptera, Dryophthoridae).

Izdebska AM et al (2023).; Ann Agric Environ Med.
DOI:: 10.26444/aaem/163326
PubMed:: 37772516

15.

Satureja montana and Mentha pulegium essential oils' antimicrobial properties against Pseudomonas syringae pv. actinidiae and elicitor potential through the modulation of kiwifruit hormonal defenses.

Summary

Essential oils from Mentha pulegium and Satureja montana were tested for their ability to combat kiwifruit bacterial canker. S. montana oil was found to be the most effective, boosting defense hormone levels and reducing infection levels. However, more research is needed to understand how it works and if it can be a long-term solution.

Antimicrobial Endocrinology

Oliveira-Fernandes J et al (2023).; Microbiol Res.
DOI:: 10.1016/j.micres.2023.127490
PubMed:: 37722185

16.

Mentha pulegium: A Plant With Several Medicinal Properties.

Amtaghri S, Slaoui M and Eddouks M (2023).; Endocr Metab Immune Disord Drug Targets.
DOI:: 10.2174/1871530323666230914103731
PubMed:: 37711001

17.

Monitoring Genetic Erosion of Aromatic and Medicinal Plant Species in Alentejo (South Portugal).

Póvoa O et al (2023).; Plants (Basel).
DOI:: 10.3390/plants12142588
PubMed:: 37514203

18.

The combined effect of essential oils on wood physico-chemical properties and their antiadhesive activity against mold fungi: application of mixture design methodology.

Sadiki M et al (2023).; Biofouling.
DOI:: 10.1080/08927014.2023.2236029
PubMed:: 37477240

19.

Essential oils and extracts of plants as biocides against microorganisms isolated from the ruins of the Roman city of Conímbriga (Portugal).

Mateus DMR et al (2023).; Environ Sci Pollut Res Int.
DOI:: 10.1007/s11356-023-28212-6
PubMed:: 37326731

20.

Non-Chinese herbal medicines for functional dyspepsia.

Review

Báez G et al (2023).; Cochrane Database Syst Rev.
DOI:: 10.1002/14651858.CD013323.pub2
PubMed:: 37323050

21.

Novel Approach for a Controlled Delivery of Essential Oils during Long-Term Maize Storage: Clove Bud and Pennyroyal Oils Efficacy to Control Sitophilus zeamais, Reducing Grain Damage and Post-Harvest Losses.

Sousa PAS et al (2023).; Insects.
DOI:: 10.3390/insects14040366
PubMed:: 37103181

22.

Variability in Chemical Composition and Antimicrobial Activity of Mentha pulegium L. Essential Oil, Cultivated Under Different Plant Growth Promoting Rhizobacteria.

Antimicrobial Phytochemistry

Djerrad Z, Terfi S and Brakchi L (2023).; Chem Biodivers.
DOI:: 10.1002/cbdv.202300002
PubMed:: 37084277

23.

Functional Quality, Antioxidant Capacity and Essential Oil Percentage in Different Mint Species Affected by Salinity Stress.

Immunology Phytochemistry

Hosseini SJ et al (2023).; Chem Biodivers.
DOI:: 10.1002/cbdv.202200247
PubMed:: 36882906

24.

Development of Dairy Products Fortified with Plant Extracts: Antioxidant and Phenolic Content Characterization.

Phytochemistry

Kandyliari A et al (2023).; Antioxidants (Basel).
DOI:: 10.3390/antiox12020500
PubMed:: 36830058

25.

Chemical composition, antioxidant, and antimicrobial activities of six commercial essential oils.

Antimicrobial Phytochemistry

Coimbra A et al (2023).; Lett Appl Microbiol.
DOI:: 10.1093/lambio/ovac042
PubMed:: 36688786

26.

Nano-scaled emulsion and nanogel containing Mentha pulegium essential oil: cytotoxicity on human melanoma cells and effects on apoptosis regulator genes.

Genetics Phytochemistry

Azadi S et al (2023).; BMC Complement Med Ther.
DOI:: 10.1186/s12906-023-03834-y
PubMed:: 36624422

27.

Pedoclimatic Conditions Influence the Morphological, Phytochemical and Biological Features of Mentha pulegium L.

Phytochemistry

Cornara L et al (2022).; Plants (Basel).
DOI:: 10.3390/plants12010024
PubMed:: 36616155

28.

Bioengineered synthesis of phytochemical-adorned green silver oxide (Ag(2)O) nanoparticles via Mentha pulegium and Ficus carica extracts with high antioxidant, antibacterial, and antifungal activities.

Antimicrobial Phytochemistry

Shahzad Shirazi M et al (2022).; Sci Rep.
DOI:: 10.1038/s41598-022-26021-4
PubMed:: 36513776

29.

Effects of Pennyroyal (Mentha pulegium L.) Supplementation on production performance, egg quality traits, and biochemical parameters of blood and egg in laying hens at later stages of the production period.

Mosayyeb Zadeh A et al (2023).; Vet Med Sci.
DOI:: 10.1002/vms3.1031
PubMed:: 36495177

30.

Formulation of nanoemulsion carriers containing Pennyroyal (Mentha pulegium) and Gijavash (Froriepia subpinnata) essential oils for enriching Doogh (Iranian dairy drink).

Phytochemistry

Habibvand M et al (2022).; IET Nanobiotechnol.
DOI:: 10.1049/nbt2.12106
PubMed:: 36478175

31.

Origanum vulgare ethanolic extracts as a promising source of compounds with antimicrobial, anti-biofilm, and anti-virulence activity against dental plaque bacteria.

Antimicrobial

Idir F et al (2022).; Front Microbiol.
DOI:: 10.3389/fmicb.2022.999839
PubMed:: 36406439

32.

Evaluation of in vitro antibacterial effect of essential oil and some herbal plant extract used against mastitis pathogens.

Phytochemistry

Arbab S et al (2022).; Vet Med Sci.
DOI:: 10.1002/vms3.959
PubMed:: 36253877

33.

Green synthesis of multifunctional ZnO/chitosan nanocomposite film using wild Mentha pulegium extract for packaging applications.

Alamdari S et al (2022).; Surf Interfaces.
DOI:: 10.1016/j.surfin.2022.102349
PubMed:: 36160476

34.

Nutritionally rich biochemical profile in essential oil of various Mentha species and their antimicrobial activities.

Antimicrobial Phytochemistry

Fazal H et al (2023).; Protoplasma.
DOI:: 10.1007/s00709-022-01799-2
PubMed:: 35943630

35.

Mentha pulegium L. (Pennyroyal, Lamiaceae) Extracts Impose Abortion or Fetal-Mediated Toxicity in Pregnant Rats; Evidenced by the Modulation of Pregnancy Hormones, MiR-520, MiR-146a, TIMP-1 and MMP-9 Protein Expressions, Inflammatory State, Certain Related Signaling Pathways, and Metabolite Profiling via UPLC-ESI-TOF-MS.

Immunology

El-Gazar AA et al (2022).; Toxins (Basel).
DOI:: 10.3390/toxins14050347
PubMed:: 35622593

36.

Chemical Composition and Synergistic Potential of Mentha pulegium L. and Artemisia herba alba Asso. Essential Oils and Antibiotic against Multi-Drug Resistant Bacteria.

Antimicrobial Phytochemistry

Bekka-Hadji F et al (2022).; Molecules.
DOI:: 10.3390/molecules27031095
PubMed:: 35164360

37.

Green Fabrication of Bioactive Silver Nanoparticles Using Mentha pulegium Extract under Alkaline: An Enhanced Anticancer Activity.

Cancer

Wang Y and Wei S (2021).; ACS Omega.
DOI:: 10.1021/acsomega.1c06267
PubMed:: 35036812

38.

Tunisian Native Mentha pulegium L. Extracts: Phytochemical Composition and Biological Activities.

Phytochemistry

Jebali J et al (2022).; Molecules.
DOI:: 10.3390/molecules27010314
PubMed:: 35011545

39.

Antispasmodic Potential of Medicinal Plants: A Comprehensive Review.

Review

Rauf A et al (2021).; Oxid Med Cell Longev.
DOI:: 10.1155/2021/4889719
PubMed:: 34804367

40.

Characterization of essential oils and volatiles from the aerial parts of Mentha pulegium L. (Lamiaceae) using microwave-assisted hydrodistillation (MAHD) and headspace solid phase microextraction (HS-SPME) in combination with GC-MS.

Phytochemistry

Mohammadhosseini M, Venditti A and Mahdavi B (2023).; Nat Prod Res.
DOI:: 10.1080/14786419.2021.1960523
PubMed:: 34328036

41.

Mentha pulegium L.: A Plant Underestimated for Its Toxicity to Be Recovered from the Perspective of the Circular Economy.

Caputo L et al (2021).; Molecules.
DOI:: 10.3390/molecules26082154
PubMed:: 33918091

42.

Essential oil of Mentha pulegium induces anthelmintic effects and reduces parasite-associated oxidative stress in rodent model.

Phytochemistry

Sebai E et al (2021).; Exp Parasitol.
DOI:: 10.1016/j.exppara.2021.108105
PubMed:: 33812980

43.

Persian Herbal Medicine in Functional Dyspepsia: A Systematic Review.

Azimi M and Zahedi MJ (2021).; Curr Drug Discov Technol.
DOI:: 10.2174/1570163817666200611132831
PubMed:: 32525777

44.

Pennyroyal Oil.

Review

(2020).
PubMed:: 31643984

45.

The Effect of Mentha Pulegium on Healing of Burn Wound Injuries in Rat.

Vaghardoost R, Ghavami Y and Sobouti B (2019).; World J Plast Surg.
DOI:: 10.29252/wjps.8.1.43.
PubMed:: 30873361

46.

Mentha pulegium Aqueous Extract Exhibits Antidiabetic and Hepatoprotective Effects in Streptozotocin-Induced Diabetic Rats.

Diabetes

Farid O et al (2019).; Endocr Metab Immune Disord Drug Targets.
DOI:: 10.2174/1871530318666181005102247
PubMed:: 30289084