Common Names: mulberry, white mulberry
This study investigated the effects of white mulberry extract on various aspects of health in patients with type 2 diabetes.
Scientists studied Morus alba L. for its antiviral properties against various viruses. It shows potential against influenza and SARS-CoV-2, but more research is needed for pseudorabies virus.
Researchers isolated 15 new stilbenoids from the tree , showing potential as antidiabetic agents. Albaphenols A, C, and E exhibit unique structures and strong α-glucosidase inhibition. Mulberrofuran G displays potent antihyperglycemic activity in diabetic mice.
Plant-derived flavonoids, especially flavones and isoflavones, show promise as novel antimicrobial agents against MRSA. They disrupt membrane structures, inhibit efflux pumps and β-lactamases, and bacterial virulence factors. This research could lead to new treatments for MRSA infections.
Mulberry leaf has potential as a natural remedy for obesity and hyperlipidemia, offering a safe and effective option for prevention and control of these major health issues.
Inhibitors of PTP1B, an enzyme involved in insulin signaling and diabetes, were screened using CE. Traditional Chinese Medicine showed strong inhibition, with fast analysis time, making it a valuable tool for drug discovery.
Moracin D from Morus alba L. has potential for treating pancreatic cancer due to its anti-inflammation, anti-breast cancer, Alzheimer's disease activity. Further research needed for its effectiveness and mechanisms.
Study investigates bacterial exchanges between plant phyllospheres and insect cuticles, elucidating their potential biological function. Understanding could inform strategies for pest management and crop protection in agriculture.
Scientists tested compounds derived from Aspergillus terreus for antimicrobial properties. They found strong potential against tuberculosis, MRSA, and various fungal strains. In silico studies confirmed their effectiveness and suggested they could be effective against Cryptococcus neoformans and as mosquito larvicidal agents.
Researchers tested the efficacy of morusin, a flavone found in white mulberry bark, against various strains of tuberculosis. Morusin showed potential as a alternative or precursor drug for TB treatment, but further studies are needed to understand its mechanism and test it on clinical isolates.
Researchers found that mulberry leaf water extract (MLWE) can improve type 2 diabetes by regulating gut microbiota and reducing intestinal permeability. This is important for understanding the potential benefits of MLWE in treating metabolic dysfunction.
Phenolics in mulberry leaves inhibit sugar digestion and uptake, regulate glucose metabolism, and improve glucose metabolism. Luteoforol and p-coumaric acid are the primary phenolics responsible for the hypoglycemic effect. They can be used as dietary supplements to regulate glucose metabolism.
BHQJ is a traditional Chinese herbal remedy made from 7 plants. It effectively treats cough asthma and reduces airway inflammation.
Mulberry leaves contain compounds that can lower blood sugar levels and have been used in traditional Chinese medicine for diabetes. However, the specific effects and mechanisms of these compounds are not well understood.
This article reviews the natural source, pharmacokinetics, and pharmacological activities of astragalin (AG), a natural flavonoid found in various edible plants. AG has therapeutic effects against several diseases, making it a potential functional food for disease therapy.
Scientists found that morusinol, a compound from L., has potential as an anticancer agent for colorectal cancer. It inhibits cell growth, promotes cell death, and induces autophagy in cancer cells by affecting cholesterol metabolism. Animal models confirmed its ability to impede tumor growth, making it a potential candidate for CRC treatment.
Mulberroside F reduced airway inflammation, eosinophil infiltration, and Th2-cell activation in asthmatic mice. It also decreased lung fibrosis and inflammatory cytokines. Promising treatment for asthma.
Herbal extracts like Moringa oleifera and Boswellia serrata have been shown to improve liver function in diabetes. They contain phenolic compounds that protect the liver through various mechanisms, including improving glucose metabolism and antioxidant defense.
Mulberry leaf's therapeutic effect on type 2 diabetes is confirmed, but we don't know how it works. This study used proteomics to investigate the mechanism in skeletal muscle.
This review summarizes the characteristics and uses of mulberry leaves (MLs) in Traditional Chinese Medicine. MLs have multiple bioactive effects that can help treat diabetes and its complications. It serves as a reference for utilizing MLs in preventing and treating diabetes.
A study on Morus alba cultivars in Italy found variations in nutritional value and biological activity. Some compounds correlated strongly with activity, and levels decreased as fruits ripened, impacting consumption and economic value.
Morus alba fruit extract has antioxidant and acetylcholinesterase inhibitory effects, improving memory disorders in mice by restoring antioxidant levels and reducing oxidative stress.
This study compared the chemical and bioactive compounds in mulberry leaves grown in Syria. Different mulberry species varied in composition and antioxidant activity. Mulberry leaves hold potential for food supplements and medical applications.
White mulberry, known as Linn, shows promise as a traditional medicine for diabetes and neuroprotection. Relevant for lab decisions.
Recent studies have found that morusin, a natural compound derived from the root bark of Morus Alba, shows promise in treating various types of cancers, such as breast, gastric, and prostate cancer. However, its effectiveness against melanoma cells remains unexplored. The discovery of new anti-melanoma drugs is urgently needed in the medical field, and understanding the potential of morusin could lead to the development of effective treatments with low side effects.
The study investigated the effects of SZ-A, a newly approved antidiabetic drug, on diabetic nephropathy. It provides valuable insights for potential treatment options and improving the health outcomes of patients with this complication.
Morusin, a compound found in mulberry tree bark, has diverse biological properties, including anti-inflammatory, anti-microbial, neuro-protective, and antioxidant capabilities. It has also shown promise as an anti-tumor agent against various types of cancers. Scientists are now investigating the potential of morusin as an alternative treatment for drug-resistant malignancies. Recent research has shed light on the therapeutic benefits of morusin, particularly in the context of human health and its anti-cancer effects. This review aims to provide an up-to-date discussion of morusin's role in cancer treatment, with a focus on and studies. These findings may pave the way for developing new polyphenolic medicines for cancer management.
L. leaf extract reduces weight gain, improves lipid accumulation and glucose sensitivity in obese mice by improving gut microbiota and reducing inflammation.
This study found that including Morus alba fruit extract in the diets of mice improved memory function. The experiment had two phases: one where the mice were given the fruit extract before memory impairment was induced and another where the extract was given after memory impairment had occurred. Cognitive function was measured using the Morris Water Maze test and brain biochemistry and histopathology were also studied. The results showed that including the fruit extract in the diet prevented and attenuated memory impairment in mice by reducing central cholinergic activity, decreasing oxidative stress, and preventing neurodegeneration.
Researchers used computer simulations and lab tests to identify natural products that can fight against the SARS-CoV-2 virus, which causes COVID-19. They screened over 140,000 natural substances, identified 38 potential hits, and tested them in lab experiments. Five of those compounds were effective at inhibiting the virus in vitro, and three of them, known as mulberry Diels-Alder-type adducts, showed potent anti-SARS-CoV-2 activity in cells. These compounds bind to the virus in a butterfly-shaped way, as confirmed through nuclear magnetic resonance experiments.