Common Names: cowitch
Preliminary study on Mucuna pruriens (MP) and Levodopa for Parkinson's disease showed both improved cognitive function and reduced neuroinflammation. MP may have similar effects as Levodopa, suggesting potential as a treatment.
Researchers tested Tribulus terrestris and Mucuna pruriens supplements on young Nile tilapia. Both raised male traits and testosterone, with better growth and survival than 17α-methyl testosterone, showing potential for sex reversal in aquaculture.
Review on the potential of nutrition and plant extracts in managing Parkinson's disease (PD) symptoms. Highlights role in neuroprotection, targeting multiple pathways implicated in PD. Challenges in translating findings into clinical practice discussed. Important for improving quality of life for PD patients.
Scientists investigated L-DOPA biosynthesis in faba bean, revealing differential accumulation in different tissues. Understanding this process could enhance L-DOPA content in crops, offering potential benefits for Parkinson's disease treatment.
Scientists propose Mucuna pruriens as a cost-effective alternative to levodopa for Parkinson's disease treatment in low-income countries. More research needed on safety and efficacy before widespread use. Ensure proper cultivation and storage for clinical trials.
Various medicinal plants show promising anticancer activity against HER2-positive breast cancer cells by reducing HER2 expression, altering proteome profile, and containing multiple anticancer compounds. Potential innovative therapies for HER2-positive breast cancer.
Mucuna pruriens, a natural source of levodopa, shows promise for treating Parkinson's disease. Clinical trial shows it extends ON time and has fewer side effects compared to standard treatment.
Globally, male infertility is a major problem and reactive oxygen species (ROS) contribute to 80% of idiopathic cases. Medicinal plants like Mucuna pruriens and Flemingia praecox can improve male fertility by eliminating ROS. This study confirms the higher antioxidant activity of F. praecox and suggests its use in managing male infertility.
Various bioactive metabolites found in herbs such as Rosmarinus officinalis and Punica granatum have shown impressive angiotensin converting enzyme (ACE) inhibitory activity. These natural ACE inhibitors could be a potential treatment for hypertension, respiratory distress syndrome, and chronic kidney diseases, but more clinical trials are needed.
Study evaluated the effects of a nicotine-free herbal formulation on smoking cessation and related health parameters. Quitting smoking is crucial to prevent various health problems, and this study explores alternative methods.
This study looked at the biological potential and phytochemicals of three Methi species. They performed anti-acetylcholinesterase and anti-lipase assays and found that one species had the highest inhibition percentage and cytotoxic potential against certain cell lines. They also identified several bioactive therapeutic compounds that could be useful in the pharmaceutical industry.
Researchers investigated the effects of pre-treatment with a seed extract and its bioactive molecule on gene expression in a rat model of cerebral ischemia (reduced blood flow to the brain). Rats were divided into four groups, with those treated with the extract or molecule showing lower neurological deficits and reduced brain damage compared to those in the control group. The study suggests that pre-treatment with the molecule and extract may reduce the negative effects of cerebral ischemia.
The study investigated the use of a traditional Ayurvedic medicine, Mucuna pruriens, as an anti-Parkinson's agent due to the toxicity of current treatment options. The study found that the seed extract showed significant neuroprotective properties and inhibitory activity against acetylcholinesterase, a target in treating Parkinson's disease. The extract containing L-dopa was found to have a superior benefit compared to synthetic L-dopa. This implies that the administration of the seed extract may be a promising treatment option for neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.
This review explores the therapeutic potential of Mucuna pruriens (Mp), a legume known for its antioxidant, anti-inflammatory, and anti-microbial properties. Mp has been widely used as an aphrodisiac and has been shown to have neuroprotective effects in Parkinson's disease (PD) models. The important constituents responsible for the anti-Parkinsonian activity of Mp are levodopa (L-DOPA), ursolic acid, and betulinic acid. The seeds of Mp are rich in L-DOPA and have been found to exhibit potent neuroprotective attributes in toxin-induced PD models. Clinical trials on anti-PD activity of Mp have shown convincing results. Mp also shows therapeutic activity in diseases such as cancer, diabetes, skin infection, and anemia. However, further studies are needed to validate its efficacy in other neurodegenerative diseases.
Parkinson's disease (PD) is a disease of the nervous system that causes loss of certain brain cells, leading to movement problems like tremors or stiffness. It may be caused by oxidative stress and an imbalance of reactive oxygen species (ROS). Certain herbal products may contain compounds that act as antioxidants and could be helpful in treating PD. This review summarized the active compounds present in herbal extracts including Baicalei, Curcuma longa, and Paeoniae Alba Radix, among others. These extracts could be useful for designing future treatments for PD.