Myristica fragrans

Common Names: nutmeg

Ethnobotanical Studies

Studies

Mechanism of apoptosis in oral squamous cell carcinoma promoted by cardamonin through PI3K/AKT signaling pathway.

Wu Y et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-71817-1
PubMed:
39242879

Evaluation of the Shelf Life of Myristica-fragrans Powder-Flavored Oils Obtained through the Application of Two Processes: Infusion and Co-Pressing Technology.

Custureri IMG et al (2024).
Molecules.
DOI:
10.3390/molecules29153588
PubMed:
39124992

Wound healing effect of nutmeg (Myristica fragrans) cream on second-degree burn in animal model.

Angilia C et al (2024).
Narra J.
DOI:
10.52225/narra.v4i1.621
PubMed:
38798873

The holocentricity in the dioecious nutmeg (Myristica fragrans) is not based on major satellite repeats.

Kuo YT et al (2024).
Chromosome Res.
DOI:
10.1007/s10577-024-09751-1
PubMed:
38717688

Herbal Spices as Food and Medicine: Microscopic Authentication of Commercial Herbal Spices.

Khan A et al (2024).
Plants (Basel).
DOI:
10.3390/plants13081067
PubMed:
38674476

The functional and structural characterisation of the bZIP transcription factors from Myristica fragrans Houtt. associated to plant disease-resistant defence: An insight from transcriptomics and computational modelling.

Genetics
Sarmah P et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.131817
PubMed:
38670182

Determination of higenamine in common natural spices by ultrahigh-performance liquid chromatography-tandem mass spectrometry.

Phytochemistry
Du J et al (2024).
Drug Test Anal.
DOI:
10.1002/dta.3672
PubMed:
38440922

Effect of nutmeg essential oil (Myristica fragrans Houtt.) on methane production, rumen fermentation, and nutrient digestibility in vitro.

Phytochemistry
Abdillah AE et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-52532-3
PubMed:
38347010

Termiticidal, biochemical, and morpho-histological effects of botanical based nanoemulsion against a subterranean termite, Odontotermes Formosanus Shiraki.

Nasser R et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1292272
PubMed:
38259939

The Identification and Cytotoxic Evaluation of Nutmeg (Myristica fragrans Houtt.) and Its Substituents.

Khamnuan S et al (2023).
Foods.
DOI:
10.3390/foods12234211
PubMed:
38231602

Anti‑adipogenic effect and underlying mechanism of lignan‑enriched nutmeg extract on 3T3‑L1 preadipocytes.

Summary

A study investigated the effect of nutmeg extract on fat accumulation in preadipocytes. The extract reduced lipid accumulation by decreasing STAT3 phosphorylation and FAS expression, suggesting potential anti-adipogenic properties.

Phytochemistry
Perumal NL et al (2023).
Biomed Rep.
DOI:
10.3892/br.2023.1692
PubMed:
38124767

Effect of Simmering Technology on Components and Activity of Myristica fragrans Houtt.

Sun J et al (2023).
Molecules.
DOI:
10.3390/molecules28227627
PubMed:
38005349

Nectandrin B significantly increases the lifespan of Drosophila - Nectandrin B for longevity.

Ahn JS et al (2023).
Aging (Albany NY).
DOI:
10.18632/aging.205234
PubMed:
37983180

Macelignan prevents colorectal cancer metastasis by inhibiting M2 macrophage polarization.

Summary

Researchers investigated the effect of macelignan, a compound found in Myristica fragrans, on the polarization of tumor-associated macrophages in colorectal cancer metastasis. Understanding this interaction can potentially lead to new strategies for cancer treatment. (37 words)

CancerGastroenterologyImmunology
Che N et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155144
PubMed:
37925889

Facile fabrication of carboxymethylcellulose/ZnO/g-C3N4 containing nutmeg extract with photocatalytic performance for infected wound healing.

Youshi M, Farahpour MR and Tabatabaei ZG (2023).
Sci Rep.
DOI:
10.1038/s41598-023-45921-7
PubMed:
37907545

Fabrication of Biogenic Titanium Nanoparticles and Investigating Their Biological Properties for Dental Applications.

A S S et al (2023).
Cureus.
DOI:
10.7759/cureus.44209
PubMed:
37767269

Insights into the inhibitory activities of neolignans and diarylnonanoid derivatives from nutmeg (Myristica fragrans Houtt.) seeds on soluble epoxide hydrolase using in vitro and in silico approaches.

Oanh VT et al (2023).
J Enzyme Inhib Med Chem.
DOI:
10.1080/14756366.2023.2251099
PubMed:
37638797

Rapid Determination of Nutmeg Shell Content in Ground Nutmeg Using FT-NIR Spectroscopy and Machine Learning.

Drees A et al (2023).
Foods.
DOI:
10.3390/foods12152939
PubMed:
37569208

Widely Targeted Volatilomics and Metabolomics Analysis Reveal the Metabolic Composition and Diversity of Zingiberaceae Plants.

Zhang Y et al (2023).
Metabolites.
DOI:
10.3390/metabo13060700
PubMed:
37367858

Safety and efficacy of a feed additive consisting of an essential oil from the seeds of Myristica fragrans Houtt. (nutmeg oil) for all animal species (FEFANA asbl).

Phytochemistry
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2023).
EFSA J.
DOI:
10.2903/j.efsa.2023.8066
PubMed:
37333988

Corrigendum: Effects of dietary nutmeg (Myristica fragrans) seed meals on growth, non-specific immune indices, antioxidant status, gene expression analysis, and cold stress tolerance in zebrafish (Danio rerio).

GeneticsImmunology
Vakili F et al (2023).
Front Nutr.
DOI:
10.3389/fnut.2023.1210933
PubMed:
37284651

Myristica fragrans Extract Inhibits Platelet Desialylation and Activation to Ameliorate Sepsis-Associated Thrombocytopenia in a Murine CLP-Induced Sepsis Model.

Jeong SH et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24108863
PubMed:
37240208

Screening for Neuroprotective and Rapid Antidepressant-like Effects of 20 Essential Oils.

Summary

This study screened essential oils for their potential as rapid-acting antidepressants. PC12 and BV2 cells were tested, and effective oils were given to mice, which were then subjected to behavioral tests. In vivo experiments showed that six essential oils decreased immobility time in the tail suspension test, with two oils increasing time and entries into the open arms of the elevated plus maze. Four compounds had a strong affinity for glutamate receptor subunits and are predicted to underlie the fast-acting effect. These oils and compounds are promising candidates for further study as fast-acting antidepressants.

Neuroscience
Tran KN et al (2023).
Biomedicines.
DOI:
10.3390/biomedicines11051248
PubMed:
37238920

Essential Oils and Sustainability: In Vitro Bioactivity Screening of Myristica fragrans Houtt. Post-Distillation By-Products.

Trifan A et al (2023).
Plants (Basel).
DOI:
10.3390/plants12091741
PubMed:
37176799

Survivability of Lactobacillus plantarum in nutmeg (Myristica fragrans Houtt) flesh extract and its effect on the performance of broiler chicken.

Sapsuha Y, Hasan S and Nur A (2023).
J Adv Vet Anim Res.
DOI:
10.5455/javar.2023.j650
PubMed:
37155539

CD8(+) T Cell-Mediated Therapeutic Antitumor Effect of an Herbal Mixture Containing Ganoderma lucidum.

Summary

An herbal medicine used in Japan for cancer patients was found to have a therapeutic effect on tumor growth by suppressing it through CD8 T cells. This is the first scientific evidence of its contribution to tumor immunity.

Cancer
Takaku S, Shimizu M and Morita R (2023).
Evid Based Complement Alternat Med.
DOI:
10.1155/2023/9630816
PubMed:
37152373

Chemical Synthesis Enables the Configurational Determination of Myristriol, a Highly Oxygenated Phenylpropanoid from Myristica fragrans Houtt.

Xiao WW et al (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202201075
PubMed:
36762483

Integrating network pharmacology and experimental models to investigate the efficacy of QYHJ on pancreatic cancer.

Cancer
Yang PW et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115516
PubMed:
35817247

Nutmeg (Myristica fragrans Houtt.) essential oil: A review on its composition, biological, and pharmacological activities.

Review Phytochemistry
Ashokkumar K et al (2022).
Phytother Res.
DOI:
10.1002/ptr.7491
PubMed:
35567294

Myristica fragrans promotes ABCA1 expression and cholesterol efflux in THP-1-derived macrophages.

Immunology
Liu S et al (2021).
Acta Biochim Biophys Sin (Shanghai).
DOI:
10.1093/abbs/gmaa146
PubMed:
33434281

Prominent Pancreatic Lipase Inhibition and Free Radical Scavenging Activity of a Myristica fragrans Ethanolic Extract in vitro. Potential Role in Obesity Treatment.

Obesity
Vangoori Y, Dakshinamoorthi A and Kavimani S (2019).
Maedica (Bucur).
DOI:
10.26574/maedica.2019.14.3.254
PubMed:
31798741

Efficacy of Myristica fragrans and Terminalia chebula as Pulpotomy Agents in Primary Teeth: A Clinical Study.

Mali S et al (2018).
Int J Clin Pediatr Dent.
DOI:
10.5005/jp-journals-10005-1565
PubMed:
31303738

Nutmeg.

Review
(2021).
PubMed:
30000898