Myrtus communis

Common Names: myrtle

Ethnobotanical Studies

Clinical Trials

Scenting serenity: influence of essential-oil vaporization on dental anxiety - a cluster-randomized, controlled, single-blinded study (AROMA_dent).

Study shows essential-oil vaporization reduces dental anxiety, especially in females and those with high trait anxiety. Promising potential for alleviating dental fear and improving patient comfort. Further research needed.

Czakert J et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-63657-w
PubMed:
38898054

The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study.

Researchers developed a new skin care product specifically for adult female acne, addressing the lack of long-term management studies. This could provide guidance for individuals and laboratories dealing with this common condition.

Bagatin E et al (2023).
J Eur Acad Dermatol Venereol.
DOI:
10.1111/jdv.18795
PubMed:
36729399

Comparison of the effect of Myrtus communis herbal and anti-hemorrhoid ointments on the hemorrhoid symptoms and quality of life in postpartum women with grade I and II internal hemorrhoid: A triple-blinded randomized controlled clinical trial.

This study compared the effect of Myrtus communis herbal ointment and anti-hemorrhoid ointment on symptoms of hemorrhoids. Results showed both ointments reduced symptoms, but the herbal ointment was more effective in reducing anal itching. Overall, the use of Myrtus communis ointment may promote the health of women with hemorrhoids.

Malekuti J et al (2019).
J Complement Integr Med.
DOI:
10.1515/jcim-2018-0147
PubMed:
31433782

Studies

Formulation of a Three-Component Essential Oil Mixture from Lavandula dentata, Rosmarinus officinalis, and Myrtus communis for Improved Antioxidant Activity.

ImmunologyPhytochemistry
Elbouzidi A et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17081071
PubMed:
39204175

Examination of genetic lines of Myrtus communis as potential sources of organic agricultural pest control agents.

Quinn E et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e35658
PubMed:
39170561

Antioxidant and antimicrobial activities of Myrtus communis essential oils in cold-stored lactic butter.

Summary

Researchers studied how adding M. communis essential oils to heat-treated cream affects the antioxidant and antimicrobial properties of lactic butter. This could lead to new dairy products with health benefits.

AntimicrobialImmunology
Keceli TM and Mertoglu TS (2024).
J Sci Food Agric.
DOI:
10.1002/jsfa.13791
PubMed:
39092905

Purification of Potential Antimicrobial Metabolites from Endophytic Fusarium oxysporum Isolated from Myrtus communis.

Summary

Endophytic fungi from Myrtus communis and Moringa oleifera, particularly Fusarium oxysporum, produced bioactive compounds with potential antimicrobial activity against drug-resistant pathogens like P. aeruginosa and E. faecalis.

Antimicrobial
Khattak SU et al (2024).
Appl Biochem Biotechnol.
DOI:
10.1007/s12010-024-05016-z
PubMed:
39083194

Antimycobacterial and Anticancer Properties of Myrtus communis Leaf Extract.

Summary

Researchers studied the antimicrobial properties of plant-derived products, specifically focusing on a medicinal herb native to the Mediterranean region. Understanding these properties could lead to new treatments for infections and diseases.

Cancer
Mir MA et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17070872
PubMed:
39065723

Chemical Characterization and Biological Activities Evaluation of Myrtus communis L. Essential Oil Extraction By-Product towards Circular Economy and Sustainability.

Phytochemistry
Abdessemed M et al (2024).
Foods.
DOI:
10.3390/foods13142211
PubMed:
39063295

Myrtus communis leaf compounds as novel inhibitors of quorum sensing-regulated virulence factors and biofilm formation: In vitro and in silico investigations.

Khadraoui N et al (2024).
Biofilm.
DOI:
10.1016/j.bioflm.2024.100205
PubMed:
38988475

Antimicrobial, Anti-inflammatory, and Wound Healing Properties of Myrtus communis Leaf Methanolic Extract Ointment on Burn Wound Infection Induced by Methicillin-Resistant Staphylococcus aureus in Rats.

Summary

Researchers tested various treatments on rats with MRSA-infected burns. Results showed Myrtus ointment had best antimicrobial and wound healing effects, making it a potential treatment option in fighting MRSA infections.

AntimicrobialImmunology
Jafari Z et al (2024).
Biomed Res Int.
DOI:
10.1155/2024/6758817
PubMed:
38899039

Histological and biochemical effects of an ethanolic extract of Myrtus communis leaf on the pancreases of rats fed high fat diets.

Kabatas GS et al (2024).
Biotech Histochem.
DOI:
10.1080/10520295.2024.2355212
PubMed:
38805000

Biofilm of Cutibacterium acnes: a target of different active substances.

Ruffier d'Epenoux L et al (2024).
Int J Dermatol.
DOI:
10.1111/ijd.17194
PubMed:
38760974

The effect of Myrtus communis L. extract on nephrolithiasis model in rats.

Ertas B et al (2024).
North Clin Istanb.
DOI:
10.14744/nci.2023.09068
PubMed:
38757104

Ameliorative effects of Myrtus communis L. extract involving the inhibition of oxidative stress on high fat diet-induced testis damage in rats.

Summary

HFD caused testicular injury in rats, affecting sperm parameters and increasing oxidative damage. MC extract may protect against these effects by inhibiting oxidative damage.

Immunology
Coskunlu B et al (2024).
Biotech Histochem.
DOI:
10.1080/10520295.2024.2344491
PubMed:
38682543

Supercritical CO(2) Extraction of Fatty Acids, Phytosterols, and Volatiles from Myrtle (Myrtus communis L.) Fruit.

Cvitković D et al (2024).
Molecules.
DOI:
10.3390/molecules29081755
PubMed:
38675575

Antibacterial Effect of Eight Essential Oils against Bacteria Implicated in Bovine Mastitis and Characterization of Primary Action Mode of Thymus capitatus Essential Oil.

Phytochemistry
Aouadhi C et al (2024).
Antibiotics (Basel).
DOI:
10.3390/antibiotics13030237
PubMed:
38534672

Evaluating the Incorporation of Myrtus communis L. Leaves Infusion in Alginate-Based Films and Spheres to Enhance the Oxidative Stability of Oil-in-Water Emulsions.

El Hammadi N et al (2024).
Polymers (Basel).
DOI:
10.3390/polym16050649
PubMed:
38475332

Effect of Myrtus communis L. Plant Extract as a Milk Supplement on the Performance, Selected Blood Parameters and Immune Response of Holstein Calves.

Uyarlar C et al (2024).
Animals (Basel).
DOI:
10.3390/ani14050725
PubMed:
38473110

Comparison of the Scolicidal Activity of Two Leaves Extracts of Myrtus communis from Algeria Against Echinococcus granulosus Sensu Lato Protoscoleces.

Benmarce M et al (2024).
Acta Parasitol.
DOI:
10.1007/s11686-024-00808-z
PubMed:
38436864

Chemical Composition Antioxidant and Anti-Inflammatory Activities of Myrtus communis L. Leaf Extract: Forecasting ADMET Profiling and Anti-Inflammatory Targets Using Molecular Docking Tools.

Immunology
Belahcene S et al (2024).
Molecules.
DOI:
10.3390/molecules29040849
PubMed:
38398601

The therapeutic value of Myrtus communis L.: an updated review.

Review
Al-Snafi AE et al (2024).
Naunyn Schmiedebergs Arch Pharmacol.
DOI:
10.1007/s00210-024-02958-3
PubMed:
38319389

Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies.

Summary

Plants and their active constituents can potentially treat diabetic foot syndrome, promoting wound healing, reducing inflammation, and stimulating angiogenesis. These alternatives could decrease amputations and offer affordable options. Further research is needed for a better understanding.

Review Diabetes
Yadav JP et al (2024).
Inflammopharmacology.
DOI:
10.1007/s10787-023-01407-6
PubMed:
38212535

Ethnobotanical study of traditional medicinal plants used by the local people in Habru District, North Wollo Zone, Ethiopia.

Summary

This study explores the use of medicinal plants in the Habru District of Ethiopia. The objective is to gather information on the plant species and traditional practices used by the local community to treat human ailments.

Ethnobotany
Alemu M et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00644-x
PubMed:
38178202

Plants as Symbols of Power in the Achaemenid Iconography of Ancient Persian Monuments.

Caneva G, Lazzara A and Hosseini Z (2023).
Plants (Basel).
DOI:
10.3390/plants12233991
PubMed:
38068625

Optimisation of Almond-Based Dairy-Free Milk Alternative Formulation Fortified with Myrtle, Bay Leaf and Fennel Extracts(§).

Balbino S et al (2023).
Food Technol Biotechnol.
DOI:
10.17113/ftb.61.03.23.8002
PubMed:
38022885

Effects of Chloride and Sulfate Salts on Seed Germination and Seedling Growth of Ballota hirsuta Benth. and Myrtus communis L.

Dadach M et al (2023).
Plants (Basel).
DOI:
10.3390/plants12223906
PubMed:
38005803

Chemo- and bio-informatics insight into anti-cholinesterase potentials of berries and leaves of Myrtus communis L., Myrtaceae: an in vitro/in silico study.

Hussein BA, Karimi I and Yousofvand N (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04241-z
PubMed:
37990185

Antibacterial Activity of Essential Oils Combinations based on Thymus broussonnetii, and Their Synergism with some Antibiotics.

Amassmoud O et al (2023).
Curr Microbiol.
DOI:
10.1007/s00284-023-03510-x
PubMed:
37910319

In Vitro Antioxidant and Antifungal Activities of Four Essential Oils and Their Major Compounds against Post-Harvest Fungi Associated with Chickpea in Storage.

Summary

This study evaluated the antifungal and antioxidant properties of essential oils derived from four plants. The EO with the highest antioxidant and antifungal activity was found to contain a high concentration of eugenol. Combining eugenol and carvacrol in a 1:3 ratio showed promising potential for grain protection during storage.

AntimicrobialImmunology
Et-Tazy L et al (2023).
Plants (Basel).
DOI:
10.3390/plants12203587
PubMed:
37896050

Unveiling the Chemical Profiling Antioxidant and Anti-Inflammatory Activities of Algerian Myrtus communis L. Essential Oils, and Exploring Molecular Docking to Predict the Inhibitory Compounds against Cyclooxygenase-2.

Immunology
Belahcene S et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16101343
PubMed:
37895814

Carboxymethyl chitosan-gelatin-mesoporous silica nanoparticles containing Myrtus communis L. extract as a novel transparent film wound dressing.

Haririan Y et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.127081
PubMed:
37769781

Antimicrobial Effects and Antioxidant Activity of Myrtus communis L. Essential Oil in Beef Stored under Different Packaging Conditions.

Summary

This study found that myrtle essential oil has antimicrobial effects on pathogenic and spoilage microorganisms in beef. It has potential as a natural alternative for enhancing meat safety and preventing microbial growth.

AntimicrobialImmunologyPhytochemistry
Moura D et al (2023).
Foods.
DOI:
10.3390/foods12183390
PubMed:
37761099

In vitro and ex vitro propagation of Turkish myrtles through conventional and plantform bioreactor systems.

Şimşek Ö et al (2023).
PeerJ.
DOI:
10.7717/peerj.16061
PubMed:
37744226

The combined effect of essential oils on wood physico-chemical properties and their antiadhesive activity against mold fungi: application of mixture design methodology.

Sadiki M et al (2023).
Biofouling.
DOI:
10.1080/08927014.2023.2236029
PubMed:
37477240

A review of the biological effects of Myrtus communis.

Review
Dabbaghi MM et al (2023).
Physiol Rep.
DOI:
10.14814/phy2.15770
PubMed:
37464095

Acknowledging the use of botanicals to treat diabetic foot ulcer during the 21(st) century: A systematic review.

Summary

DFU is a common and serious problem for diabetics. Treating it is difficult, particularly for people with weak immune systems.

Diabetes
Narzary I et al (2023).
World J Clin Cases.
DOI:
10.12998/wjcc.v11.i17.4035
PubMed:
37388781

Compounds from myrtle flowers as antibacterial agents and SARS-CoV-2 inhibitors: In-vitro and molecular docking studies.

Summary

Myrtle flower essential oil, containing 54 compounds, demonstrates antibacterial activity and potential for developing drugs against Gram-negative bacteria and SARS-CoV-2. (25 words)

COVID-19
Barhouchi B et al (2023).
Arab J Chem.
DOI:
10.1016/j.arabjc.2023.104939
PubMed:
37193561

Antioxidant Activity and Inhibition of Digestive Enzymes of New Strawberry Tree Fruit/Apple Smoothies.

Immunology
Gil KA et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12040805
PubMed:
37107180

The Leaf Essential Oil of Myrtus communis subsp. tarentina (L.) Nyman: From Phytochemical Characterization to Cytotoxic and Antimigratory Activity in Human Prostate Cancer Cells.

CancerPhytochemistry
Giuliani C et al (2023).
Plants (Basel).
DOI:
10.3390/plants12061293
PubMed:
36986980

Generation of Highly Antioxidant Submicron Particles from Myrtus communis Leaf Extract by Supercritical Antisolvent Extraction Process.

Valor D et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12020530
PubMed:
36830088

Change in Cutibacterium acnes phylotype abundance and improvement of clinical parameters using a new dermocosmetic product containing Myrtus communis and Celastrol enriched plant cell culture extracts in patients with acne vulgaris.

Dermatology
Mias C et al (2023).
J Eur Acad Dermatol Venereol.
DOI:
10.1111/jdv.18792
PubMed:
36729402

Myrtus communis and Celastrol enriched plant cell culture extracts control together the pivotal role of Cutibacterium acnes and inflammatory pathways in acne.

DermatologyImmunology
Mias C et al (2023).
J Eur Acad Dermatol Venereol.
DOI:
10.1111/jdv.18793
PubMed:
36729401

Simplex-centroid design as innovative approach in the optimization of antimicrobial effect of Thymus satureioides, Myrtus communis and Artemisia herba alba essential oils against Escherichia coli, Staphylococcus aureus and Candidatropicalis.

AntimicrobialPhytochemistry
Chraibi M et al (2023).
Exp Parasitol.
DOI:
10.1016/j.exppara.2023.108472
PubMed:
36693583

Optimizing the Antimicrobial Synergism of Melaleuca alternifolia (Tea Tree) Essential Oil Combinations for Application against Respiratory Related Pathogens.

AntimicrobialPhytochemistry
Rapper SL, Viljoen A and van Vuuren S (2023).
Planta Med.
DOI:
10.1055/a-1947-5680
PubMed:
36626923

Effect of Apple Juice Enrichment with Selected Plant Materials: Focus on Bioactive Compounds and Antioxidant Activity.

Gil KA et al (2022).
Foods.
DOI:
10.3390/foods12010105
PubMed:
36613321

Antileukemic, Antioxidant, Anti-Inflammatory and Healing Activities Induced by a Polyphenol-Enriched Fraction Extracted from Leaves of Myrtus communis L.

ImmunologyPhytochemistry
Mechchate H et al (2022).
Nutrients.
DOI:
10.3390/nu14235055
PubMed:
36501085

In vitro and in vivo copper-treated Myrtus communis L.: terpene profiles and evidence for potential cultivation on metal-contaminated soils.

Phytochemistry
Capuana M et al (2022).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-022-24484-6
PubMed:
36474036

Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity.

Summary

Six plant essential oils commonly used in Iranian Traditional Medicine for memory improvement were tested for their ability to inhibit cholinesterase, an enzyme whose inhibition is a key target in the treatment of Alzheimer's disease. The plants tested were cinnamon, myrtle, rue, dill, nutmeg, and saffron. These findings may support the continued use of these natural remedies for memory improvement and suggest the potential of using these plants for developing drugs to treat AD.

NeurosciencePhytochemistry
Saeedi M et al (2022).
BMC Complement Med Ther.
DOI:
10.1186/s12906-022-03767-y
PubMed:
36401242

Assessment of anthelmintic potentials of Myrtus communis against Haemonchus contortus and Heligmosomoides polygyrus.

Sebai E et al (2022).
Exp Parasitol.
DOI:
10.1016/j.exppara.2022.108320
PubMed:
35779645

Biological control of Citrus brown spot pathogen, "Alternaria alternata" by different essential oils.

Grati Affes T et al (2023).
Int J Environ Health Res.
DOI:
10.1080/09603123.2022.2055748
PubMed:
35322739

Myrtus communis improves cognitive impairment in renovascular hypertensive rats.

Summary

A study investigated the effects of Myrtus communis extract on cognitive function in rats with renovascular hypertension (RVH). The rats were divided into 4 groups and underwent tests for object recognition and spatial memory. Blood brain barrier integrity was also examined along with various biochemical parameters in the hippocampal tissue. The RVH group showed decreased cognitive function and impaired BBB permeability. The Myrtus communis extract treatment group showed improvement in cognitive function and restoration of biochemical parameters. The study suggests that Myrtus communis extract may improve cognitive function in hypertension through its various activities.

Neuroscience
Cevikelli-Yakut ZA et al (2020).
J Physiol Pharmacol.
DOI:
10.26402/jpp.2020.5.07
PubMed:
33475094

Antibacterial Triketone-Phloroglucinol-Triketone Adducts from Myrtus communis.

Wu Y et al (2020).
Chem Biodivers.
DOI:
10.1002/cbdv.202000708
PubMed:
32935916

Myrtus communis subsp. communis improved cognitive functions in ovariectomized diabetic rats.

Summary

Researchers explored whether Myrtus communis subsp. communis (MC) could alleviate cognitive impairment in diabetic rats that had undergone ovariectomy. To test their hypothesis, the team performed various experiments on the rodents and found that MC significantly improved their cognitive function. The study indicates that MC could serve as a potential therapeutic agent for brain-related disorders in both menopausal women with diabetes and those without the condition.

DiabetesNeuroscience
Kadıoğlu Yaman B et al (2020).
Gene.
DOI:
10.1016/j.gene.2020.144616
PubMed:
32222531

Myrtus communis Liquor Byproduct as a Source of Bioactive Compounds.

Correddu F et al (2019).
Foods.
DOI:
10.3390/foods8070237
PubMed:
31262099

Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review.

Review
Hennia A, Miguel MG and Nemmiche S (2018).
Medicines (Basel).
DOI:
10.3390/medicines5030089
PubMed:
30103510

Myrtus communis L. and its application in treatment of Recurrent Aphthous Stomatitis.

Review
Mahboubi M et al (2016).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2016.09.054
PubMed:
27693775