Nerium oleander

Common Names: oleander

Ethnobotanical Studies

Studies

Evaluating larvicidal, ovicidal and growth inhibiting activity of five medicinal plant extracts on Culex pipiens (Diptera: Culicidae), the West Nile virus vector.

Baz MM et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-69449-6
PubMed:
39191818

Effects of the recovery period after particulate matter pollution events on the dust retention capacity and physiological characteristics of Nerium oleander.

Diao H et al (2024).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2024.174990
PubMed:
39094640

Charge generation by passive plant leaf motion at low wind speeds: design and collective behavior of plant-hybrid energy harvesters.

Meder F et al (2024).
Bioinspir Biomim.
DOI:
10.1088/1748-3190/ad5ba1
PubMed:
38917810

PBI-05204, a supercritical CO(2) extract of Nerium oleander, suppresses glioblastoma stem cells by inhibiting GRP78 and inducing programmed necroptotic cell death.

Chakraborty S et al (2024).
Neoplasia.
DOI:
10.1016/j.neo.2024.101008
PubMed:
38823209

Potential Anti-Tumorigenic Properties of Diverse Medicinal Plants against the Majority of Common Types of Cancer.

Summary

Study shows natural products from plants have potential in cancer therapy. Phytochemicals regulate molecular pathways, offering chemo-preventive benefits. Literature review highlights medicinal plants' anticancer effects and mechanisms. Important for developing targeted treatments.

Review Cancer
Albahri G et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17050574
PubMed:
38794144

Assessment of bioremediation potential of Calotropis procera and Nerium oleander for sustainable management of vehicular released metals in roadside soils.

Anjum S et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-58897-9
PubMed:
38637588

Assessment of seasonal variations in particulate matter accumulation and elemental composition in urban tree species.

Moura BB et al (2024).
Environ Res.
DOI:
10.1016/j.envres.2024.118782
PubMed:
38570123

Preliminary investigation of the safe dose of oleandrin when administered orally to Beagles.

Fossum TW, Newman RA and Matos JR (2024).
J Am Vet Med Assoc.
DOI:
10.2460/javma.23.11.0651
PubMed:
38503057

An appraisal of traditional knowledge of plant poisoning of livestock and its validation through acute toxicity assay in rats.

Rasool F et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1328133
PubMed:
38420196

Diversity and distribution of Phytophthora species across different types of riparian vegetation in Italy with the description of Phytophthora heteromorpha sp. nov.

Bregant C et al (2024).
Int J Syst Evol Microbiol.
DOI:
10.1099/ijsem.0.006272
PubMed:
38407194

Poisoning by Nerium oleander L. in Franconia Geese.

Pugliese N et al (2024).
Animals (Basel).
DOI:
10.3390/ani14040612
PubMed:
38396580

Protective efficacy of Nerium oleander extract on spermatogenesis in streptozotocin-induced diabetic rats.

Summary

In this study, researchers examined the effects of the hydro-alcoholic extract of leaves on the reproductive health of healthy and diabetic rats. Results showed that lower doses of the extract improved testicular morphology, sperm parameters, and antioxidant levels, suggesting its potential to protect against diabetic-induced spermatogenic dysfunction.

Diabetes
Karimi A et al (2024).
Zygote.
DOI:
10.1017/S0967199423000643
PubMed:
38284273

Oleander attenuates hepatic inflammation in a TLR4-independent manner and by favorable modulation of hepatocellular global metabolome that supports cytoprotection.

Summary

Nerium oleander, a plant used in traditional medicine, has hepatoprotective effects according to Indian and Chinese literature. Relevant for potential treatments of liver-related metabolic diseases.

Immunology
Dey P et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117717
PubMed:
38181937

A suicide attempt by ingestion of oleander leaves and treatment with digoxin-specific Fab antibody fragments.

Kovačević T et al (2023).
Arh Hig Rada Toksikol.
DOI:
10.2478/aiht-2023-74-3752
PubMed:
38146758

Accidental fatal poisoning in a child due to ingestion of Nerium oleander leaf.

Ayyappan S, N A and Toi PC (2023).
Forensic Sci Med Pathol.
DOI:
10.1007/s12024-023-00771-7
PubMed:
38133853

Deliberate Self-Poisoning with Plants in Southeastern France, a Poison Center 20-Year Report.

Torrents R et al (2023).
Toxins (Basel).
DOI:
10.3390/toxins15120671
PubMed:
38133175

Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel.

Mantelli G et al (2023).
Toxicol Rep.
DOI:
10.1016/j.toxrep.2023.10.010
PubMed:
37885923

Seasonal Differences in Leaf Photoprotective Potential between Adults and Juveniles of Two Mediterranean Perennials with Distinct Growth Forms: A Comparative Field Study.

Chondrogiannis C et al (2023).
Plants (Basel).
DOI:
10.3390/plants12173110
PubMed:
37687356

Differential Activities of the Botanical Extract PBI-05204 and Oleandrin on Innate Immune Functions under Viral Challenge Versus Inflammatory Culture Conditions.

Immunology
Jensen GS et al (2023).
Molecules.
DOI:
10.3390/molecules28124799
PubMed:
37375354

Potential plant leaves as sustainable green coagulant for turbidity removal.

Khalid Salem A, Fadhile Almansoory A and Al-Baldawi IA (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e16278
PubMed:
37251892

Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre-clinical studies published from 2010 to 2020.

Summary

Researchers conducted a systematic review of scientific articles published between 2010 and 2020 that evaluated the anxiolytic, sedative, and/or hypnotic effects of flower extracts in pre-clinical animal models. They found that some flower extracts have an anxiolytic effect comparable to diazepam, but their therapeutic utility in anxiety disorders needs more investigation. The study compiled the characteristics of anxiety studies in animal models, evaluated locomotor activity, and the hypnotic effect of the extracts. The study revealed that matricaria chamomilla had a sedative effect, and 23 other flower plants had anxiolytic effects. However, more reliable behavioral tests and better experimental designs are needed to obtain more conclusive evidence with clinical significance.

Review Neuroscience
Meneses C et al (2023).
Phytother Res.
DOI:
10.1002/ptr.7830
PubMed:
37039741

Organic-inorganic composite modifiers enhance restoration potential of Nerium oleander L. to lead-zinc tailing: application of phytoremediation.

Su R et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-26359-w
PubMed:
36920611

Exploring of the ameliorative effects of Nerium (Nerium oleander L.) ethanolic flower extract in streptozotocin induced diabetic rats via biochemical, histological and molecular aspects.

Diabetes
Battal A et al (2023).
Mol Biol Rep.
DOI:
10.1007/s11033-023-08332-5
PubMed:
36897524

Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo.

Cancer
Rashan LJ et al (2023).
Molecules.
DOI:
10.3390/molecules28041871
PubMed:
36838857

Nerium oleander could be used for sustainable management of traffic-borne elemental-enriched roadside soils.

Khalid N et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-25160-z
PubMed:
36622593

Capacity of Nerium oleander to Phytoremediate Sb-Contaminated Soils Assisted by Organic Acids and Oxygen Nanobubbles.

Seridou P et al (2022).
Plants (Basel).
DOI:
10.3390/plants12010091
PubMed:
36616220

Phytotoxic Interference of Culture Filtrates of Endophytic Bacteria Associated with Nerium oleander Leaf Against Seed Germination of the Invasive Noxious Weed Cenchrus echinatus.

Hagaggi NSA and Abdul-Raouf UM (2023).
Curr Microbiol.
DOI:
10.1007/s00284-022-03166-z
PubMed:
36607432

The botanical drug PBI-05204, a supercritical CO(2) extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo.

Vaccaro S et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.1071176
PubMed:
36532747

Detection of Highly Poisonous Nerium oleander Using Quantitative Real-Time PCR with Specific Primers.

Bai X et al (2022).
Toxins (Basel).
DOI:
10.3390/toxins14110776
PubMed:
36356026

Species-specific efficiency in PM(2.5) removal by urban trees: From leaf measurements to improved modeling estimates.

Gaglio M et al (2022).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2022.157131
PubMed:
35798105

Renal Lesions in Horses with Oleander (Nerium oleander) Poisoning.

Sykes CA et al (2022).
Animals (Basel).
DOI:
10.3390/ani12111443
PubMed:
35681907

Commodity risk assessment of Nerium oleander plants from Turkey.

EFSA Panel on Plant Health (PLH) et al (2021).
EFSA J.
DOI:
10.2903/j.efsa.2021.6569
PubMed:
33976712

Toxicity effects of Nerium oleander, basic and clinical evidence: A comprehensive review.

Review
Farkhondeh T et al (2020).
Hum Exp Toxicol.
DOI:
10.1177/0960327120901571
PubMed:
31971021

Subacute Toxicity of Nerium oleander Ethanolic Extract in Mice.

Abdou RH, Basha WA and Khalil WF (2019).
Toxicol Res.
DOI:
10.5487/TR.2019.35.3.233
PubMed:
31341552

Oleander (Nerium oleander).

Cassileth B et al (2010).
Oncology (Williston Park).
PubMed:
21192568

A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander) poisoning.

Review
Bandara V et al (2010).
Toxicon.
DOI:
10.1016/j.toxicon.2010.03.026
PubMed:
20438743