Ocimum tenuiflorum

Common Names: holy basil

Ethnobotanical Studies

Studies

Busting the Resistance: Antimicrobial Activity of Plant-Infused Nanoemulsions against Neisseria gonorrhoeae.

Summary

Plant nanoemulsions from Durban Botanical Gardens were tested for antimicrobial properties against antibiotic-resistant gonorrhoea strains. Results show potential as a safer alternative treatment option.

Antimicrobial
Naicker D, Govender R and Abbai NS (2024).
Int J Microbiol.
DOI:
10.1155/2024/7084347
PubMed:
39109214

Deciphering the multi-target therapeutic capabilities of Ocimum tenuiflorum Linn. Compounds against systemic lupus erythematosus and inflammatory bowel disease: a network pharmacology and molecular modelling approach.

DermatologyImmunology
Kumar S and Sarkar B (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2388792
PubMed:
39105677

Essential oil and waste hydrosol of Ocimum tenuiflorum L.: A low-cost raw material source of eugenol, botanical pesticides, and therapeutic potentiality.

Phytochemistry
Le DG et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202401161
PubMed:
39073007

Comparative Anti-inflammatory Activity of a Nanocomposite-Based Herbal Oral Rinse and a Commercial Oral Rinse.

Summary

Study compared anti-inflammatory effects of commercial vs nanocomposite oral rinse in vitro. Results may help in developing improved oral care products for inflammation management.

Immunology
Divakar A et al (2024).
Cureus.
DOI:
10.7759/cureus.61548
PubMed:
38962586

GC-MS analysis of an ethanolic extract of Ocimum species: a network pharmacology analysis insight towards obesity.

Summary

Tulsi plants contain bioactive compounds with potential anti-obesity effects. OTRT has benzenepropanoic acid, while OTKT has methyl 3-(4-benzyloxy-3,5-dimethoxyphenyl)-2-methylpropanoate. Targets include SRC, BCL2, EGFR, MTOR, CDK1, ERBB2, MAPK1, FYN, AR, and MAPK14.

Obesity
Gnanamurthy P, Narasimhan MK and Sabarathinam S (2024).
Future Sci OA.
DOI:
10.2144/fsoa-2023-0202
PubMed:
38827792

Phytomediated stress modulates antioxidant status, induces overexpression of CYP6M2, Hsp70, α-esterase, and suppresses the ABC transporter in Anopheles gambiae (sensu stricto) exposed to Ocimum tenuiflorum extracts.

Immunology
Aremu HK et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0302677
PubMed:
38696463

Bioactive compounds from Ocimum tenuiflorum and Poria cocos: A novel natural Compound for insomnia treatment based on A computational approach.

Ranteh O et al (2024).
Comput Biol Med.
DOI:
10.1016/j.compbiomed.2024.108491
PubMed:
38657467

Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health.

Review
Patibandla S et al (2024).
Cureus.
DOI:
10.7759/cureus.55240
PubMed:
38558676

Antimicrobial Activity of Silver Nanoparticles Synthesized Using Ocimum tenuiflorum and Ocimum gratissimum Herbal Formulations.

Summary

Researchers utilized herbal extracts from and to synthesize silver nanoparticles with antimicrobial properties against oral pathogens. Results showed high efficacy against certain bacteria, suggesting potential for dental applications and improved oral healthcare.

Antimicrobial
Varghese RM, S AK and Shanmugam R (2024).
Cureus.
DOI:
10.7759/cureus.54994
PubMed:
38550426

Development of an allele-specific PCR (AS-PCR) method for identifying high-methyl eugenol-containing purple Tulsi (Ocimum tenuiflorum L.) in market samples.

Genetics
Balaji R and Parani M (2024).
Mol Biol Rep.
DOI:
10.1007/s11033-024-09365-0
PubMed:
38520476

Green cleanup of styrene-contaminated soil by carbon-based nanoscale zero-valent iron and phytoremediation: Sunn hemp (Crotalaria juncea), zinnia (Zinnia violacea Cav.), and marigold (Tagetes erecta L.).

Kambhu A et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e27499
PubMed:
38496887

Antimicrobial Activity of Zinc Oxide Nanoparticles Synthesized Using Ocimum Tenuiflorum and Ocimum Gratissimum Herbal Formulation Against Oral Pathogens.

Summary

TL;DR: Scientists used green methods to create zinc oxide nanoparticles that effectively inhibited oral pathogens. Candida albicans was most sensitive, indicating potential selectivity. This research shows promise for using these nanoparticles in oral health.

Antimicrobial
Varghese RM, S AK and Shanmugam R (2024).
Cureus.
DOI:
10.7759/cureus.53562
PubMed:
38445144

Cytotoxicity and Characterization of Zinc Oxide and Silver Nanoparticles Synthesized Using Ocimum tenuiflorum and Ocimum gratissimum Herbal Formulation.

Varghese RM, S AK and Shanmugam R (2024).
Cureus.
DOI:
10.7759/cureus.53481
PubMed:
38440033

Comparative Anti-inflammatory Activity of Silver and Zinc Oxide Nanoparticles Synthesized Using Ocimum tenuiflorum and Ocimum gratissimum Herbal Formulations.

Immunology
Varghese RM, S AK and Shanmugam R (2024).
Cureus.
DOI:
10.7759/cureus.52995
PubMed:
38406168

Enhancing growth, vitality, and aromatic richness: unveiling the dual magic of silicon dioxide and titanium dioxide nanoparticles in Ocimum tenuiflorum L.

Bhat UH et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1335965
PubMed:
38384769

Chemical composition and mosquitocidal properties of essential oil from Indian indigenous plants Ocimum tenuiflorum L. and Ocimum americanum L. against three vector mosquitoes.

Phytochemistry
Ragavendran K et al (2024).
Exp Parasitol.
DOI:
10.1016/j.exppara.2024.108709
PubMed:
38301765

The complete chloroplast genome of Orthosiphon aristatus (Blume) Miq. (Lamiaceae).

Summary

The study analyzed the complete chloroplast genome of (Blume) Miq. 1858, a medicinal plant. It found that the plant forms a monophyletic group within Lamiaceae, aiding in species identification and phylogenetic analysis.

Genetics
Su Y et al (2024).
Mitochondrial DNA B Resour.
DOI:
10.1080/23802359.2023.2301012
PubMed:
38222982

Anti-inflammatory and Antioxidant Activity of Ocimum tenuiflorum- and Stevia rebaudiana-Mediated Silver Nanoparticles: An In Vitro Study.

Immunology
Pandiyan I et al (2023).
Cureus.
DOI:
10.7759/cureus.50109
PubMed:
38192947

Benefits of basil tea for patients with differentiated thyroid cancer during radioiodine therapy: A randomized controlled trial.

Summary

Researchers investigated the psychological and physical effects of radioactive iodine therapy for thyroid cancer patients, highlighting the importance of considering both aspects for better patient care.

CancerEndocrinology
Nomura K, Nakayama M and Okizaki A (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e20691
PubMed:
37829808

Metabolome profiling of arbuscular mycorrhizal fungus treated Ocimum tenuiflorum L. provides insights into deviation in allocation of carbon compounds to secondary metabolism.

Thokchom SD et al (2023).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2023.108039
PubMed:
37717347

Chemical Composition, In vitro and In silico evaluation of essential oil from Ocimum tenuiflorum and Coriandrum sativum Linn for lung cancer.

Summary

This paper analyzes the chemical composition and medicinal potential of essential oils from Ocimum tenuiflorum and Coriandrum sativum. Useful for understanding potential treatments for various diseases.

CancerPhytochemistry
Singh B et al (2023).
Curr Comput Aided Drug Des.
DOI:
10.2174/1573409920666230831144716
PubMed:
37653637

BDMediLeaves: A leaf images dataset for Bangladeshi medicinal plants identification.

Islam S et al (2023).
Data Brief.
DOI:
10.1016/j.dib.2023.109488
PubMed:
37636130

Tag and Snag: A New Platform for Bioactive Natural Product Screening from Mixtures.

Seidel J et al (2023).
Molecules.
DOI:
10.3390/molecules28155726
PubMed:
37570695

Characterizing the circadian connectome of Ocimum tenuiflorum using an integrated network theoretic framework.

Singh V and Singh V (2023).
Sci Rep.
DOI:
10.1038/s41598-023-40212-7
PubMed:
37567911

Potential antihypertensive activity of novel peptides from green basil leaves.

Prangthip P, Panbangred W and Reamtong O (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04098-2
PubMed:
37553559

Antimicrobial and Cytotoxic Activity of Ocimum tenuiflorum and Stevia rebaudiana-Mediated Silver Nanoparticles - An In vitro Study.

Summary

Researchers extracted silver nanoparticles from a medicinal plant used in Ayurvedic medicine. Understanding their properties and applications could benefit scientific advancements in various fields.

Antimicrobial
Pandiyan I et al (2023).
Contemp Clin Dent.
DOI:
10.4103/ccd.ccd_369_21
PubMed:
37547431

A survey of Phytophthora spp. in eastern Indian nurseries and their sensitivity to six oomycete targeted commercial fungicides.

Dhali R et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-10-22-2341-RE
PubMed:
37498632

A comparison of high- and low-resolution gas chromatography-mass spectrometry for herbal product classification: A case study with Ocimum essential oils.

Phytochemistry
Abraham EJ, Wallace ED and Kellogg JJ (2023).
Phytochem Anal.
DOI:
10.1002/pca.3258
PubMed:
37393908

Incredible Combination of Lifestyle Modification and Herbal Remedies for Polycystic Ovarian Syndrome Management.

Summary

Researchers reviewed the use of yoga and herbal remedies for polycystic ovarian syndrome (PCOS), a common hormonal disorder. These alternative therapies can help improve symptoms and quality of life, offering a holistic approach to PCOS management. Further research is needed to validate these findings.

Review Endocrinology
Balkrishna A et al (2023).
Evid Based Complement Alternat Med.
DOI:
10.1155/2023/3705508
PubMed:
37383339

Choice Modeling for the Commercial Cultivation of Underutilized Aromatic Plants for Producing Mosquito Repellents: Targeting Rural Sector Income Generation.

Munugoda KD et al (2023).
Econ Bot.
DOI:
10.1007/s12231-023-09573-y
PubMed:
37359047

Synthesis of Transition-Metal-Doped Nanocatalysts with Antibacterial Capabilities Using a Complementary Green Method.

Singh A et al (2023).
Molecules.
DOI:
10.3390/molecules28104182
PubMed:
37241922

Formulation and Evaluation of Quality Parameters of Effervescent Granules from the Potent Antioxidant between Two Variants of the Adaptogenic Herb Ocimum tenuiflorum L.

Immunology
Parajuli-Baral K et al (2023).
ScientificWorldJournal.
DOI:
10.1155/2023/2050846
PubMed:
37144025

Ocimum tenuiflorum extract (HOLIXERTM): Possible effects on hypothalamic-pituitary-adrenal (HPA) axis in modulating stress.

C M MG et al (2023).
PLoS One.
DOI:
10.1371/journal.pone.0285012
PubMed:
37141281

Antimicrobial efficiency of Tinospora cordifolia and Ocimum tenuiflorum against Streptococcus mutans and Candida albicans.

Antimicrobial
Shivakumar VH, Tegginamani AS and Zain NM (2022).
J Oral Maxillofac Pathol.
DOI:
10.4103/jomfp.jomfp_68_22
PubMed:
37082076

Structure modelling of odorant receptor from Aedes aegypti and identification of potential repellent molecules.

Tiwari V and Sowdhamini R (2023).
Comput Struct Biotechnol J.
DOI:
10.1016/j.csbj.2023.03.005
PubMed:
37013002

Exploring the Chemistry of Ocimum Species under Specific Extractions and Chromatographic Methods: A Systematic Review.

Review
Beltrán-Noboa A et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c00043
PubMed:
37008142

Bioactivation of an orthodontic wire using multifunctional nanomaterials to prevent plaque accumulation.

Anand BG et al (2023).
Biomater Adv.
DOI:
10.1016/j.bioadv.2023.213346
PubMed:
36963344

Assessment of air pollution tolerance index (APTI) and anticipated performance index (API) of selected roadside plant species for the green belt development at Ratnagiri City in the Konkan region of Maharashtra, India.

Patil PY et al (2023).
Environ Monit Assess.
DOI:
10.1007/s10661-023-11048-5
PubMed:
36943472

Improvement in the Phytochemical Content and Biological Properties of Stevia rebaudiana (Bertoni) Bertoni Plant Using Endophytic Fungi Fusarium fujikuroi.

Phytochemistry
Devi R et al (2023).
Plants (Basel).
DOI:
10.3390/plants12051151
PubMed:
36904011

Comparative assessment of the heavy metal phytoextraction potential of vegetables from agricultural soils: A field experiment.

Zunaidi AA, Lim LH and Metali F (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e13547
PubMed:
36816267

Synthesis of phytoextract-mediated Ag-doped graphitic carbon nitride (Ag@GCN) for photocatalytic degradation of dyes.

Dahiya S, Sharma A and Chaudhary S (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-25359-0
PubMed:
36696062

Synergistic Antibacterial and Anti-inflammatory Activities of Ocimum tenuiflorum Ethanolic Extract against Major Bacterial Mastitis Pathogens.

Immunology
Srichok J et al (2022).
Antibiotics (Basel).
DOI:
10.3390/antibiotics11040510
PubMed:
35453261

Effects of Ocimum tenuiflorum on Induced Testicular Degeneration by Filgrastim in Wistar Rats.

Tuimah Alabedi GS et al (2021).
Arch Razi Inst.
DOI:
10.22092/ari.2021.356079.1772
PubMed:
35355764

Ocimum tenuiflorum mitigates iron-induced testicular toxicity via modulation of redox imbalance, cholinergic and purinergic dysfunctions, and glucose metabolizing enzymes activities.

Olofinsan KA et al (2021).
Andrologia.
DOI:
10.1111/and.14179
PubMed:
34228819

Efficacy of Ocimum tenuiflorum essential oil as grain protectant against coleopteran beetle, infesting stored pulses.

Phytochemistry
Bhavya ML, Obulaxmi S and Devi SS (2021).
J Food Sci Technol.
DOI:
10.1007/s13197-020-04871-y
PubMed:
33746288

Genome-Wide Analysis of Domain-Swap Predicted Products in the Genome of Anti-Stress Medicinal Plant: Ocimum tenuiflorum.

Genetics
Upadhyay AK and Sowdhamini R (2019).
Bioinform Biol Insights.
DOI:
10.1177/1177932218821362
PubMed:
30692846

Can Ocimum basilicum L. and Ocimum tenuiflorum L. in vitro culture be a potential source of secondary metabolites?

Bhuvaneshwari K et al (2016).
Food Chem.
DOI:
10.1016/j.foodchem.2015.07.136
PubMed:
26471526

Ocimum sanctum L (Holy Basil or Tulsi) and its phytochemicals in the prevention and treatment of cancer.

Review Cancer
Baliga MS et al (2013).
Nutr Cancer.
DOI:
10.1080/01635581.2013.785010
PubMed:
23682780