Oenothera biennis

Common Names: common evening primrose, common evening-primrose, hoary eveningprimrose, king's-cureall

Ethnobotanical Studies

Clinical Trials

The Use of Evening Primrose Oil for Cervical Ripening in Low-Risk Women with Term Pregnancy: A Randomized Double-Blinded Controlled Trial.

Ariana S et al (2024).
Complement Med Res.
DOI:
10.1159/000535585
PubMed:
38377980

Studies

Evening primrose and its compounds of 1-Oxohederagenin and remangilone C ameliorate bleomycin-induced pulmonary fibrosis by regulating β-catenin signaling.

Zhang Q et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155933
PubMed:
39121537

Riparian woody plant communities in the Romanian Carpathians: Species diversity and community structure of Salix and Hippophaë communities.

Bita-Nicolae C et al (2024).
Ecol Evol.
DOI:
10.1002/ece3.11361
PubMed:
38774135

Oenothera biennis with strong copper toxicity resistance enriches trace copper in seeds under copper pollution soil.

Dong J et al (2024).
Ecotoxicol Environ Saf.
DOI:
10.1016/j.ecoenv.2024.116382
PubMed:
38677067

Identification of tyrosinase inhibitors in defatted seeds of evening primrose (Oenothera biennis L.) by affinity-labeled molecular networking.

Wang Z et al (2024).
Food Res Int.
DOI:
10.1016/j.foodres.2024.114097
PubMed:
38395549

The effect of Oenothera biennis (Evening primrose) oil on inflammatory diseases: a systematic review of clinical trials.

Immunology
Sharifi M et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04378-5
PubMed:
38360611

Uncovering the colorectal cancer immunotherapeutic potential: Evening primrose (Oenothera biennis) root extract and its active compound oenothein B targeting the PD-1/PD-L1 blockade.

Summary

Immune checkpoint inhibitors (such as PD-L1/PD-1 blockers) are effective immunotherapy drugs for cancer treatment, but their side effects restrict their use. FDA only permits monoclonal antibody-based PD-L1/PD-1 blockers.

CancerGastroenterology
Lee EJ et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155370
PubMed:
38266440

Evening primrose oil enriched with gamma linolenic acid and D/L-alpha tocopherol acetate attenuated carbon tetrachloride-induced hepatic injury model in male rats via TNF-α, IL-1β, and IL-6 pathway.

Immunology
Gad El-Hak HN, Kishk SM and Abdelrazek HMA (2024).
Toxicol Mech Methods.
DOI:
10.1080/15376516.2023.2301357
PubMed:
38166523

Effect of misoprostol with and without evening primrose (Oenothera biennis) on induction of missed abortion.

Mahmoodinasab M et al (2023).
Avicenna J Phytomed.
DOI:
10.22038/AJP.2023.22179
PubMed:
38089421

First Report of Pseudocercospora oenotherae Causing Leaf spot in Rhinacanthus nasutus in China.

Zheng C, Liu YL and Ren L (2023).
Plant Dis.
DOI:
10.1094/PDIS-08-23-1512-PDN
PubMed:
38085980

A phylogeny of the evening primrose family (Onagraceae) using a target enrichment approach with 303 nuclear loci.

Overson RP et al (2023).
BMC Ecol Evol.
DOI:
10.1186/s12862-023-02151-9
PubMed:
37974080

Oenothera biennis cell culture produce lignans activating Piezo1 triggering the Myosin Light Chain Kinase depending pathways.

Summary

Study finds that plant extract called ObHEx activates receptor Piezo1, which detects mechanical forces in body. Activation is regulated by protein MYLK, and the extract contains components Liriodendrin and Salvadoraside, highlighting potential use of natural extracts to activate Piezo1.

Phytochemistry
Tito A et al (2023).
Biochem Biophys Res Commun.
DOI:
10.1016/j.bbrc.2023.09.056
PubMed:
37748257

Evening primrose oil: a comprehensive review of its bioactives, extraction, analysis, oil quality, therapeutic merits, and safety.

Review
Farag MA et al (2023).
Food Funct.
DOI:
10.1039/d3fo01949g
PubMed:
37614101

Responses of different invasive and non-invasive ornamental plants to water stress during seed germination and vegetative growth.

Mircea DM et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-40517-7
PubMed:
37587264

LC-MS Metabolomic Profiling of Five Types of Unrefined, Cold-Pressed Seed Oils to Identify Markers to Determine Oil Authenticity and to Test for Oil Adulteration.

Sumara A et al (2023).
Molecules.
DOI:
10.3390/molecules28124754
PubMed:
37375308

First Report of Pseudocercospora oenotherae Causing Leaf spot in Hymenocallis littoralis in China.

Zheng C, Liu YL and Xie P (2023).
Plant Dis.
DOI:
10.1094/PDIS-08-22-1897-PDN
PubMed:
37311226

Nitrogen Deposition Effects on Invasive and Native Plant Competition: Implications for Future Invasions.

Guo X et al (2023).
Ecotoxicol Environ Saf.
DOI:
10.1016/j.ecoenv.2023.115029
PubMed:
37216867

Effects of salt stress on interspecific competition between an invasive alien plant Oenothera biennis and three native species.

Guo X et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1144511
PubMed:
37025129

Structure of the lipopolysaccharide O-antigen of Serratia spp. strains 10.1WK and 1XS plant endophytes isolated from O. biennis and L. corniculatus.

Swatek A et al (2023).
Carbohydr Res.
DOI:
10.1016/j.carres.2023.108760
PubMed:
36753890

Embryonic stem cell differentiation to primordial germ cell like cells by Nigella sativa, Brassica Oleracea and Oenothera biennis extracts.

Najibi R et al (2022).
Am J Stem Cells.
PubMed:
36660740

Systematic Review of Evening Primrose (Oenothera biennis) Preparations for the Facilitation of Parturition.

Review
Hutcherson TC et al (2022).
Pharmacy (Basel).
DOI:
10.3390/pharmacy10060172
PubMed:
36548328

Promitotic Action of Oenothera biennis on Senescent Human Dermal Fibroblasts.

Ceccacci S et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms232315153
PubMed:
36499490

Oxidative Stability and Protective Effect of the Mixture between Helianthus annuus L. and Oenothera biennis L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity.

Fecker R et al (2022).
Plants (Basel).
DOI:
10.3390/plants11212977
PubMed:
36365432

Evening primrose seed extract rich in polyphenols modulates the invasiveness of colon cancer cells by regulating the TYMS expression.

CancerPhytochemistry
Ciszewski WM et al (2022).
Food Funct.
DOI:
10.1039/d2fo01737g
PubMed:
36239291

Extensive population-level sampling reveals clinal variation in (R)-(-)-linalool produced by the flowers of an endemic evening primrose, Oenothera harringtonii.

Skogen KA et al (2022).
Phytochemistry.
DOI:
10.1016/j.phytochem.2022.113185
PubMed:
35436476

The effect of evening primrose oil (Oenothera biennis) on the level of adiponectin and some biochemical parameters in rats with fructose induced metabolic syndrome.

Mert H et al (2022).
Arch Physiol Biochem.
DOI:
10.1080/13813455.2020.1781900
PubMed:
32594769

Evening Primrose (Oenothera biennis) Oil in Management of Female Ailments.

Review
Mahboubi M et al (2019).
J Menopausal Med.
DOI:
10.6118/jmm.18190
PubMed:
31497576

Effects of Oenothera biennis L. and Hypericum perforatum L. extracts on some central nervous system myelin proteins, brain histopathology and oxidative stress in mice with experimental autoimmune encephalomyelitis.

Summary

This study looked at the effects of two plant extracts, Oenothera biennis and Hypericum perforatum, on brain tissue in mice with multiple sclerosis (MS). The extracts were found to decrease myelin loss, a hallmark of MS, and amyloid deposition on vascular walls. The extracts also improved antioxidant levels and decreased oxidative stress in the brain tissue of the mice. The study suggests that Oenothera biennis and Hypericum perforatum have potential therapeutic benefits for MS treatment.

Neuroscience
Selek S et al (2019).
Biotech Histochem.
DOI:
10.1080/10520295.2018.1482001
PubMed:
30957550

Evening Primrose (Oenothera biennis) Biological Activity Dependent on Chemical Composition.

Review
Timoszuk M, Bielawska K and Skrzydlewska E (2018).
Antioxidants (Basel).
DOI:
10.3390/antiox7080108
PubMed:
30110920

Evening Primrose.

Review
(2021).
PubMed:
30000954

A review of effective herbal medicines in controlling menopausal symptoms.

Review
Kargozar R, Azizi H and Salari R (2017).
Electron Physician.
DOI:
10.19082/5826
PubMed:
29403626

Herbal and plant therapy in patients with inflammatory bowel disease.

Review Immunology
Triantafyllidi A et al (2015).
Ann Gastroenterol.
PubMed:
25830661

Evening primrose oil.

Bayles B and Usatine R (2009).
Am Fam Physician.
PubMed:
20000302