Common Names: sweet marjoram
Phytochemicals from plants like celastrol and resveratrol can target autophagy and ER stress to induce cancer cell death. Understanding how different phytochemicals interact with these processes can help develop new anticancer drugs. However, more research is needed for clinical applications.
Study compared intrauterine herbal product (EUC) to antibiotic (CEPH) for treating endometritis in dairy cows. Both had similar clinical cure rates, suggesting herbal product as non-inferior alternative to reduce antibiotic use.
Study evaluated methanolic extract of leaves of () traditionally used to treat diarrhea and gut spasms. Results may lead to potential new treatment options for gastrointestinal issues.
This study examined the bioavailability and antiepileptic activity of a plant extract from L. leaves. The extract showed good antiepileptic activity by delaying seizures, possibly due to the interaction of its compounds with the NMDA receptor.
Four monoterpenes in essential oil were found to decrease cell viability, reduce colony growth, and downregulate survivin expression in non-small cell lung cancer. Combinations of monoterpenes enhanced their anticancer effects, showing potential for future research.
Researchers created a natural nanoemulsion with dual benefits: fighting bacteria and combating cancer. This has potential to lead to new treatments for both infectious diseases and cancer.
This study found that inhaling marjoram essential oil at work can potentially reduce stress and anxiety levels of nurses in a COVID-19 ICU. This may lead to better quality of patient care.
Study examined the effects of marjoram extracts on breast cancer cells and normal breast tissue cells. Marjoram extracts showed cytotoxic effect on cancer cells and no major effects on normal cells. This suggests marjoram extracts could be a promising alternative to chemotherapy for breast cancer treatment.
The chloroform extract from exhibited strong antibacterial and antifungal activity. Six compounds were isolated, including previously undescribed ones. Majoranaquinone showed high antibacterial effect, inhibition of efflux pumps, and inhibition of biofilm formation. It should be considered for antimicrobial effects of .
Researchers investigated the impact of using essential oil or methanol extract from the aerial parts of Origanum majorana to protect rats against imidacloprid-induced neurotoxicity. They found that rats given OMO or OME along with imidacloprid showed less neurobehavioral and neuropathological damage, as well as improved levels of acetylcholine esterase, dopamine, serotonin, and gamma-aminobutyric acid in the brain. Both extracts had potent antioxidant, anti-inflammatory, and anti-apoptotic effects that helped protect against imidacloprid's effects. The study recommends daily intake of Origanum majorana to protect against neuroinflammatory stress and apoptosis induced by insecticides.
The study investigated the potential of using Origanum majorana L. extract to delay the onset and progression of neurodegenerative diseases such as Alzheimer's disease. Neuroinflammation and oxidative stress were found to play a critical role in the development of these diseases. The study assessed the phytochemical characteristics of the extract and its neuroprotective effects in a mouse model of neuroinflammation. The findings indicate that natural phenolics such as Origanum majorana L. may have potent antioxidant and anti-inflammatory properties that could be useful in treating neurodegenerative diseases.
In this study, researchers evaluated the inhibitory potentials of commercial essential oils and their main component, carvacrol. The essential oils, including and , were found to inhibit angiotensin-converting enzyme 2 and lipoxygenase enzymes. Carvacrol showed the highest inhibitory activity for both enzymes. The findings suggest that these essential oils and carvacrol have potential health benefits, particularly in regulating blood pressure and inflammation. Further studies are needed to ensure their safety and effectiveness.