Orthosiphon aristatus

Ethnobotanical Studies

Studies

Sinensetin Inhibits Angiogenesis in Lung Adenocarcinoma via the miR-374c-5p/VEGF-A/VEGFR-2/AKT Axis.

Ji T et al (2024).
Cell Biochem Biophys.
PubMed:
39030333

Kidney tea [Orthosiphon aristatus (Blume) Miq.] improves diabetic nephropathy via regulating gut microbiota and ferroptosis.

Summary

Chinese herb kidney tea may offer new treatment options for diabetic nephropathy, a leading cause of end-stage renal disease. Further research needed to understand its mechanisms and potential as a therapeutic agent.

Zhou Z et al (2024).
Front Pharmacol.
PubMed:
38962302

Isolation, structure modification, and anti-rheumatoid arthritis activity of isopimarane-type diterpenoids from Orthosiphon aristatus.

Summary

Researchers identified new compounds from a herb and created derivatives. The compounds displayed anti-rheumatoid arthritis activity and inhibited inflammatory proteins.

Luo YX et al (2024).
J Enzyme Inhib Med Chem.
PubMed:
38234133

The complete chloroplast genome of Orthosiphon aristatus (Blume) Miq. (Lamiaceae).

Summary

The study analyzed the complete chloroplast genome of (Blume) Miq. 1858, a medicinal plant. It found that the plant forms a monophyletic group within Lamiaceae, aiding in species identification and phylogenetic analysis.

Su Y et al (2024).
Mitochondrial DNA B Resour.
PubMed:
38222982

A Study of the Medicinal Plants of Genus Orthosiphon sp.: Aiming to Expand Valuable Medicinal Resources for Medical Treatment.

Thieu VD et al (2023).
Pak J Biol Sci.
PubMed:
38193373

The immunomodulatory activity of Orthosiphon aristatus against atopic dermatitis: Evidence-based on network pharmacology and molecular simulations.

Summary

Tested the effectiveness of OA on atopic dermatitis. Care because OA could be a potential treatment for AD.

Pandaleke TA et al (2023).
J Taibah Univ Med Sci.
PubMed:
38047238

Potential of rosmarinic acid from Orthosiphon aristatus extract for inflammatory induced diseases and its mechanisms of action.

Mohmad Saberi SE and Chua LS (2023).
Life Sci.
PubMed:
37827234

Orthosiphon aristatus (Blume) Miq. Extracts attenuate Alzheimer-like pathology through anti-inflammatory, anti-oxidative, and β-amyloid inhibitory activities.

Summary

Scientists studied the traditional herb Orthosiphon aristatus and found that it contains phenols and flavonoids with anti-inflammatory and antioxidant properties. This information is important as it suggests potential benefits for treating conditions like nephritis, epilepsy, and cystitis.

Chiang KH et al (2023).
J Ethnopharmacol.
PubMed:
37704121

Potential protein hydrolysates from the white and purple flower varieties of Orthosiphon aristatus leaves.

Chua LS et al (2023).
Food Chem.
PubMed:
37651783

Study on the mechanism of Orthosiphon aristatus (Blume) Miq. in the treatment of hyperuricemia by microbiome combined with metabonomics.

Zhu C et al (2023).
J Ethnopharmacol.
PubMed:
37355082

Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia.

Review Cancer
Prieto JM and Hanafi MMM (2023).
Curr Issues Mol Biol.
PubMed:
36826044

Orthosiphon aristatus (Blume) Miq Alleviates Non-Alcoholic Fatty Liver Disease via Antioxidant Activities in C57BL/6 Obese Mice and Palmitic-Oleic Acid-Induced Steatosis in HepG2 Cells.

Summary

A plant extract called Miq can help to reduce non-alcoholic fatty liver disease (NAFLD) by improving liver enzymes and reducing glucose, insulin, cholesterol, and triglyceride levels. It also has antioxidant and anti-inflammatory properties.

Alshehade SA et al (2023).
Pharmaceuticals (Basel).
PubMed:
36678606

Mechanism of action of Orthosiphon stamineus against non-alcoholic fatty liver disease: Insights from systems pharmacology and molecular docking approaches.

Alshehade SA et al (2022).
Saudi Pharm J.
PubMed:
36465851

Gut Microbiota of Pigs Metabolizes Extracts of Filipendula ulmaria and Orthosiphon aristatus-Herbal Remedies Used in Urinary Tract Disorders.

Popowski D et al (2022).
Planta Med.
PubMed:
34624904

Micropropagation and Secondary Metabolites Content of White-Purple Varieties of Orthosiphon aristatus Blume Miq.

Faramayuda F et al (2021).
Pak J Biol Sci.
PubMed:
34486353

The influence of chemical composition of potent inhibitors in the hydrolyzed extracts of anti-hyperuricemic plants to their xanthine oxidase activities.

Ooi KL et al (2021).
J Ethnopharmacol.
PubMed:
34090914

A review on extraction techniques and therapeutic value of polar bioactives from Asian medicinal herbs: Case study on Orthosiphon aristatus, Eurycoma longifolia and Andrographis paniculata.

Review
Abd Aziz NA et al (2021).
Saudi Pharm J.
PubMed:
33679177

Sinensetin: An Insight on Its Pharmacological Activities, Mechanisms of Action and Toxicity.

Review
Han Jie L et al (2021).
Front Pharmacol.
PubMed:
33628166

Dietary Supplement Intake and Its Association with Cognitive Function, Physical Fitness, Depressive Symptoms, Nutritional Status and Biochemical Indices in a 3-Year Follow-Up Among Community Dwelling Older Adults: A Longitudinal Study.

Summary

This study looked at how taking dietary supplements affects the health of older adults over time. The researchers wanted to see if taking supplements improved cognitive function, physical fitness, and other measures of health. They found that taking supplements at the start of the study did not have a significant impact on these measures over the course of several years. This suggests that taking supplements may not be very effective for improving health in these areas in older adults.

Vanoh D et al (2021).
Clin Interv Aging.
PubMed:
33531799

Genotype selection for phytochemical content and pharmacological activities in ethanol extracts of fifteen types of Orthosiphon aristatus (Blume) Miq. leaves using chemometric analysis.

Batubara I et al (2020).
Sci Rep.
PubMed:
33262368

Method development for analysis of proteins extracted from the leaves of Orthosiphon aristatus.

Koay SY and Gam LH (2011).
J Chromatogr B Analyt Technol Biomed Life Sci.
PubMed:
21689998

Antioxidant and anti-inflammatory effects of Orthosiphon aristatus and its bioactive compounds.

Hsu CL et al (2010).
J Agric Food Chem.
PubMed:
20095565