Paederia foetida

Study demonstrates the antimicrobial potential of Linn. plant extract against biofilm-forming pathogens, including MRSA, through interference with quorum sensing. Bioactive compounds quercetin and kaempferol show promise, but drug-like properties need further investigation for potential as novel therapeutics against antimicrobial resistance.

Antimicrobial

Santajit S et al (2024).; Antibiotics (Basel).
DOI:: 10.3390/antibiotics13070613
PubMed:: 39061295

Active defense strategies for invasive plants may alter the distribution pattern of pests in the invaded area.

Zhai J et al (2024).; Front Plant Sci.
DOI:: 10.3389/fpls.2024.1428752
PubMed:: 39055354

Antinociceptive iridoid glycosides from the aerial parts of Paederia foetida.

Phytochemistry

Chen YF et al (2024).; J Asian Nat Prod Res.
DOI:: 10.1080/10286020.2024.2326565
PubMed:: 38469737

Assessment of the hypoglycemic and anti-hemostasis effects of Paederia foetida (L.) in controlling diabetes and thrombophilia combining in vivo and computational analysis.

Summary

The study found that the methanolic extract of P. foetida leaves (PFLE) showed no toxicity, reduced blood sugar levels, increased body weight, and had anti-hemostasis effects. Deep learning predicted that Cleomiscosins, found in PFLE, have potential as drugs for managing diabetes and thrombophilia.

Diabetes

Ferdous J et al (2023).; Comput Biol Chem.
DOI:: 10.1016/j.compbiolchem.2023.107954
PubMed:: 37738820

A delve into the pharmacological targets and biological mechanisms of Paederia foetida Linn.: a rather invaluable traditional medicinal plant.

Review

Sarma MK et al (2023).; Naunyn Schmiedebergs Arch Pharmacol.
DOI:: 10.1007/s00210-023-02496-4
PubMed:: 37099165

The complete chloroplast genome of the medicinal plant Paederia foetida L.

Genetics

Wang W et al (2022).; Mitochondrial DNA B Resour.
DOI:: 10.1080/23802359.2022.2087563
PubMed:: 35837498

Ethnoveterinary Survey Conducted in Baiku Yao Communities in Southwest China.

Ethnobotany

Luo B et al (2022).; Front Vet Sci.
DOI:: 10.3389/fvets.2021.813737
PubMed:: 35146017

Rapid Quantification and Validation of Biomarker Scopoletin in Paederia foetida by qNMR and UV-Vis for Herbal Preparation.

Phytochemistry

Tan DC et al (2020).; Molecules.
DOI:: 10.3390/molecules25215162
PubMed:: 33171900

Stimulatory Effects of Paederia foetida Flower Absolute on the Skin Wound and Barrier Repair Activities of Keratinocytes.

Kim HB et al (2020).; Chem Biodivers.
DOI:: 10.1002/cbdv.202000506
PubMed:: 32889769

10.

Evaluation of ameliorative effect of two selected plant drugs on experimentally induced arsenic toxicity in sheep.

Maji C et al (2020).; Environ Sci Pollut Res Int.
DOI:: 10.1007/s11356-020-09569-4
PubMed:: 32564325

11.

Identification of Antidiabetic Metabolites from Paederia foetida L. Twigs by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Study.

Diabetes Phytochemistry

Tan DC et al (2019).; Biomed Res Int.
DOI:: 10.1155/2019/7603125
PubMed:: 31275982

12.

Comparative study of the antidiabetic potential of Paederia foetida twig extracts and compounds from two different locations in Malaysia.

Diabetes

Tan DC et al (2019).; Pharm Biol.
DOI:: 10.1080/13880209.2019.1610462
PubMed:: 31185767

13.

Paederia foetida induces anticancer activity by modulating chromatin modification enzymes and altering pro-inflammatory cytokine gene expression in human prostate cancer cells.

Immunology

Pradhan N et al (2019).; Food Chem Toxicol.
DOI:: 10.1016/j.fct.2019.05.016
PubMed:: 31112703

14.

Ethnobotany of medicinal plants used by the Zeliangrong ethnic group of Manipur, northeast India.

Ethnobotany

Panmei R, Gajurel PR and Singh B (2019).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2019.02.009
PubMed:: 30738117

15.

Paederia foetida Linn. promoted biogenic gold and silver nanoparticles: Synthesis, characterization, photocatalytic and in vitro efficacy against clinically isolated pathogens.

Bhuyan B et al (2017).; J Photochem Photobiol B.
DOI:: 10.1016/j.jphotobiol.2017.05.040
PubMed:: 28599238

16.

Gastroprotective mechanism of Paederia foetida Linn. (Rubiaceae)--a popular edible plant used by the tribal community of North-East India.

Chanda S et al (2015).; BMC Complement Altern Med.
DOI:: 10.1186/s12906-015-0831-0
PubMed:: 26335308

17.

Paederia foetida Linn. inhibits adjuvant induced arthritis by suppression of PGE(2) and COX-2 expression via nuclear factor-κB.

Immunology

Kumar V et al (2015).; Food Funct.
DOI:: 10.1039/c5fo00178a
PubMed:: 25893742

18.

A phytochemical, pharmacological and clinical profile of Paederia foetida and P. scandens.

Review Phytochemistry

Wang L et al (2014).; Nat Prod Commun.
PubMed:: 25115105

19.

Paederia foetida Linn. leaf extract: an antihyperlipidemic, antihyperglycaemic and antioxidant activity.

Kumar V et al (2014).; BMC Complement Altern Med.
DOI:: 10.1186/1472-6882-14-76
PubMed:: 24564866

20.

Effect of ethanolic extract of leaves of Paederia foetida Linn. on acetic acid induced colitis in albino rats.

Gastroenterology

Das S et al (2013).; Indian J Pharmacol.
DOI:: 10.4103/0253-7613.117728
PubMed:: 24130378

21.

Antidiarrhoeal activity of the ethanol extract of Paederia foetida Linn. (Rubiaceae).

Afroz S et al (2006).; J Ethnopharmacol.
PubMed:: 16298094