Panax japonicus

Common Names: Japanese ginseng

Ethnobotanical Studies

Studies

Characterization and protein engineering of a novel UDP-glycosyltransferase involved in pseudoginsenoside Rt5 biosynthesis from Panax japonicus.

Li P et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.134537
PubMed:
39111463

The antiangiogenic effect of total saponins of Panax japonicus C.A. Meyer in rheumatoid arthritis is mediated by targeting the HIF-1α/VEGF/ANG-1 axis.

Summary

Researchers extracted TSPJs from Panax japonicus C.A. Meyer, a traditional Chinese herbal medicine used to treat rheumatoid arthritis. The anti-inflammatory mechanism of TSPJs needs further investigation.

ArthritisPhytochemistry
Guo X et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118422
PubMed:
38838922

Transcriptomic Analysis Under Drought and Salt Stress Provides Insight into Genes Putatively Involved in Ginsenoside Biosynthesis in Panax japonicus Meyer.

Summary

Researchers analyzed the genes of P. japonicus under drought and salt stress to identify key pathways related to triterpene saponin synthesis, potentially leading to discoveries in ginsenoside biosynthesis and signal pathways.

Genetics
Zhou J et al (2024).
Biochem Genet.
DOI:
10.1007/s10528-024-10845-y
PubMed:
38836961

Novel glycosidase from Paenibacillus lactis 154 hydrolyzing the 28-O-β-D-glucopyranosyl ester bond of oleanane-type saponins.

Phytochemistry
Wu Z et al (2024).
Appl Microbiol Biotechnol.
DOI:
10.1007/s00253-024-13109-2
PubMed:
38573330

Comprehensive Characterization of Triterpene Saponins in Rhizoma Panacis Japonici by Offline Two-Dimensional Liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry.

Phytochemistry
Yasen S et al (2024).
Molecules.
DOI:
10.3390/molecules29061295
PubMed:
38542930

Curative effect of the total saponins of Panax japonicus (TSPJ) on type 2 diabetes: Focusing on VEGFA.

Summary

The study found that TSPJ could potentially be beneficial in managing T2DM, suggesting potential implications for the treatment of the disease.

DiabetesPhytochemistry
Li S et al (2024).
Gene.
DOI:
10.1016/j.gene.2024.148305
PubMed:
38403172

Bioreactor Systems for Plant Cell Cultivation at the Institute of Plant Physiology of the Russian Academy of Sciences: 50 Years of Technology Evolution from Laboratory to Industrial Implications.

Review
Titova M, Popova E and Nosov A (2024).
Plants (Basel).
DOI:
10.3390/plants13030430
PubMed:
38337964

Polysaccharide from Panax japonicus C.A. Mey prevents non-alcoholic fatty liver disease development based on regulating liver metabolism and gut microbiota in mice.

Gastroenterology
Wu Y et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.129430
PubMed:
38228199

Total saponins from Panax japonicus attenuate acute alcoholic liver oxidative stress and hepatosteatosis by p62-related Nrf2 pathway and AMPK-ACC/PPARα axis in vivo and in vitro.

ImmunologyPhytochemistry
Qiu L et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116785
PubMed:
37321425

In-Depth Excavation and Screening of Triterpene Saponins From the Rhizome of Panax japonicus Using High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry.

Phytochemistry
Ling Y et al (2023).
J Chromatogr Sci.
DOI:
10.1093/chromsci/bmad014
PubMed:
36879549

Panax japonicus and chikusetsusaponins: A review of diverse biological activities and pharmacology mechanism.

Review
Wang XJ et al (2020).
Chin Herb Med.
DOI:
10.1016/j.chmed.2020.12.003
PubMed:
36117758

Identification of certain Panax species to be potential substitutes for Panax notoginseng in hemostatic treatments.

Review
Yang BR et al (2018).
Pharmacol Res.
DOI:
10.1016/j.phrs.2018.05.005
PubMed:
29772270

RNA-seq Transcriptome Analysis of Panax japonicus, and Its Comparison with Other Panax Species to Identify Potential Genes Involved in the Saponins Biosynthesis.

GeneticsPhytochemistry
Rai A et al (2016).
Front Plant Sci.
DOI:
10.3389/fpls.2016.00481
PubMed:
27148308