Papaver somniferum

Common Names: opium poppy

Ethnobotanical Studies

Studies

Active-Site Oxygen Accessibility and Catalytic Loop Dynamics of Plant Aromatic Amino Acid Decarboxylases from Molecular Simulations.

Gou Y, Li T and Wang Y (2024).
Biochemistry.
DOI:
10.1021/acs.biochem.4c00144
PubMed:
39008055

Alkaloid Accumulation and Distribution within the Capsules of Two Opium Poppy (Papaver somniferum L.) Varieties.

Phytochemistry
Májer P and Németh ÉZ (2024).
Plants (Basel).
DOI:
10.3390/plants13121640
PubMed:
38931072

Development of a two-layer machine learning model for the forensic application of legal and illegal poppy classification based on sequence data.

An HE et al (2024).
Forensic Sci Int Genet.
DOI:
10.1016/j.fsigen.2024.103061
PubMed:
38820740

The effects of opium consumption on severity of disease on hospitalized COVID-19 patients in East of Iran, a prospective cohort study.

Summary

Opium use impacts COVID-19 severity, with higher hypertension and urea levels, lower lymphocytes, and increased risk of hospitalization and mortality. You should care because opium use affects the outcome of COVID-19 patients.

COVID-19
Pagheh AS et al (2024).
Transl Clin Pharmacol.
DOI:
10.12793/tcp.2024.32.e4
PubMed:
38586125

New Set of EST-STR Markers for Discrimination of Related Papaver somniferum L. Varieties.

Kaňuková Š et al (2023).
Life (Basel).
DOI:
10.3390/life14010072
PubMed:
38255686

Assessing monofloral bee pollens from Türkiye: Palynological verification, phenolic profile, and antioxidant activity.

Summary

This study analyzed various monofloral bee pollen samples for their palynological analysis, antioxidant activity, phenolic profiles, and color. Different species had varying phenolic compositions and higher levels of TPC and antioxidant activity. This helps authenticate and ensure the quality of bee pollen products for the food industry.

ImmunologyPhytochemistry
Çobanoğlu DN et al (2024).
J Food Sci.
DOI:
10.1111/1750-3841.16928
PubMed:
38235995

From genomics to metabolomics: Deciphering sanguinarine biosynthesis in Dicranostigma leptopodum.

Lei W et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.128727
PubMed:
38092109

Comparison of direct analysis in real-time mass spectrometry, atmospheric solids analysis probe-mass spectrometry, and ion mobility spectrometry for ensuring food safety by rapid screening of poppy seeds.

Kern SE et al (2023).
Anal Bioanal Chem.
DOI:
10.1007/s00216-023-05042-6
PubMed:
37999721

Herbgenomics meets Papaveraceae: a promising -omics perspective on medicinal plant research.

Kielich N et al (2023).
Brief Funct Genomics.
DOI:
10.1093/bfgp/elad050
PubMed:
37952099

Evolutionary analysis of conserved non-coding elements subsequent to whole-genome duplication in opium poppy.

Summary

Researchers studied the evolutionary patterns of regulatory and coding sequences after whole-genome duplication in opium poppy. They found that regulatory element variations drove faster changes in gene expression patterns compared to coding sequences, with tissue-specific alkaloid production evolution being influenced by changes in regulatory elements. This study sheds light on the importance of regulatory element evolution in the development of new characteristics.

Genetics
Xu Y et al (2023).
Plant J.
DOI:
10.1111/tpj.16466
PubMed:
37706612

Studies on Sensory and Phytochemical Characteristics of Poppy (Papaver somniferum L.) Varieties for Their Oil Utilisation.

Phytochemistry
Gupcsó K et al (2023).
Foods.
DOI:
10.3390/foods12173165
PubMed:
37685099

Unearthed opium: development of a UHPLC-MS/MS method for the determination of Papaver somniferum alkaloids in Daunian vessels.

Summary

This study developed advanced methods to detect opium alkaloids in ancient ceramic vessels. The findings suggest ancient Daunian civilization may have used opium, providing new insights for further research.

Phytochemistry
Vincenti F et al (2023).
Front Chem.
DOI:
10.3389/fchem.2023.1238793
PubMed:
37564111

Morphology, Taxonomy, Anatomy, and Palynology of the Opium Poppy (Papaver somniferum L.) Cultivation in Northern Thailand.

Ngernsaengsaruay C et al (2023).
Plants (Basel).
DOI:
10.3390/plants12112105
PubMed:
37299086

Morphometrics of waterlogged archaeological seeds give new insights into the domestication and spread of Papaver somniferum L. in Western Europe.

Jesus A et al (2023).
PLoS One.
DOI:
10.1371/journal.pone.0286190
PubMed:
37228077

Molecular and Epigenetic Aspects of Opioid Receptors in Drug Addiction and Pain Management in Sport.

Summary

This study explores the harmful effects of opioids, their impact on addiction and overdose, and the involvement of the mesocorticolimbic dopaminergic circuitry. It also addresses the use of synthetic opioids in athletes and the potential for doping.

Review NeurosciencePain
Mazzeo F, Meccariello R and Guatteo E (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24097831
PubMed:
37175536

Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence.

Summary

This review focuses on the diverse alkaloids found in L. (Papaveraceae) and their extraction methods, particularly for morphine and codeine. It also explores the link between opium consumption and cancer.

Review CancerPhytochemistry
Vadhel A et al (2023).
Open Biol.
DOI:
10.1098/rsob.220355
PubMed:
37132222

Applicability of LC-QToF and Microscopical Tools in Combating the Sophisticated, Economically Motivated Adulteration of Poppy Seeds.

Avula B et al (2023).
Foods.
DOI:
10.3390/foods12071510
PubMed:
37048333

Papaver somniferum and Papaver rhoeas Classification Based on Visible Capsule Images Using a Modified MobileNetV3-Small Network with Transfer Learning.

Zhu J, Zhang C and Zhang C (2023).
Entropy (Basel).
DOI:
10.3390/e25030447
PubMed:
36981335

Papaver somniferum in seventeenth century (Italy): archaeotoxicological study on brain and bone samples in patients from a hospital in Milan.

Summary

Scientists analyzed preserved brain tissue and bone samples from 17th century patients of a Milan hospital. In a multidisciplinary study, toxicological and other analyses were performed on biological samples from nine individuals. Archeotoxicological testing showed the presence of opium-derived compounds, including codeine and morphine. The researchers concluded that Papaver somniferum, a plant used for its narcotic, analgesic, astringent, coagulant, and antitussive properties, was used in pharmacological therapies administered to patients. The study highlights treatments given to patients before their death and provides insight into medical practices in the 1600s.

Neuroscience
Giordano G et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-27953-1
PubMed:
36854677

Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera).

Phytochemistry
Menéndez-Perdomo IM and Facchini PJ (2023).
Sci Rep.
DOI:
10.1038/s41598-023-29415-0
PubMed:
36805479

Investigating the Effects of Biogenic Zinc Oxide Nanoparticles Produced Using Papaver somniferum Extract on Oxidative Stress, Cytotoxicity, and the Induction of Apoptosis in the THP-1 Cell Line.

Kadhim AA et al (2023).
Biol Trace Elem Res.
DOI:
10.1007/s12011-023-03574-7
PubMed:
36662347

Review
IARC Working Group on the Identification of Carcinogenic Hazards to Humans et al (2021).
PubMed:
36395294

Changes in Vitellogenin (Vg) and Stress Protein (HSP 70) in Honey Bee (Apis mellifera anatoliaca) Groups under Different Diets Linked with Physico-Chemical, Antioxidant and Fatty and Amino Acid Profiles.

Sarioğlu-Bozkurt A et al (2022).
Insects.
DOI:
10.3390/insects13110985
PubMed:
36354809

Poisonous Piperidine Plants and the Biodiversity of Norditerpenoid Alkaloids for Leads in Drug Discovery: Experimental Aspects.

Review Phytochemistry
Qasem AMA, Rowan MG and Blagbrough IS (2022).
Int J Mol Sci.
DOI:
10.3390/ijms232012128
PubMed:
36292987

Nutritional and Chemical Characterization of Poppy Seeds, Cold-Pressed Oil, and Cake: Poppy Cake as a High-Fibre and High-Protein Ingredient for Novel Food Production.

Melo D et al (2022).
Foods.
DOI:
10.3390/foods11193027
PubMed:
36230103

Opium abuse and stroke in Iran: A systematic review and meta-analysis.

Summary

Opium dependence is a serious problem in low and middle-income countries, causing considerable deaths each year. Its impact on stroke is unclear. Researchers conducted a study to evaluate the association between opium dependence and stroke. Results showed a significant association between the two, highlighting the harmful effects of opium use on stroke risk. This study sheds light on the need for public health interventions to address opium addiction to prevent stroke and save lives.

CardiologyNeuroscience
Mardi P et al (2022).
Front Neurol.
DOI:
10.3389/fneur.2022.855578
PubMed:
36188414

Computational insights into diverse aspects of glutathione S-transferase gene family in Papaver somniferum.

Vaish S et al (2022).
J Plant Res.
DOI:
10.1007/s10265-022-01408-6
PubMed:
36066757

Pharmacokinetics and transplacental transfer of codeine and codeine metabolites from Papaver somniferum L.

Chen JH et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115623
PubMed:
36007718

Development of diagnostic SNP markers and a novel SNP genotyping assay for distinguishing opium poppies.

Chang M et al (2022).
Forensic Sci Int.
DOI:
10.1016/j.forsciint.2022.111416
PubMed:
35985139

Evaluation of chloroplast DNA barcoding markers to individualize Papaver somniferum for forensic intelligence purposes.

Genetics
Graham K and Houston R (2024).
Int J Legal Med.
DOI:
10.1007/s00414-022-02862-6
PubMed:
35788906

Molecular identification and phylogenetic analysis of Papaver based on ITS2 barcoding.

Cheng L et al (2022).
J Forensic Sci.
DOI:
10.1111/1556-4029.14925
PubMed:
34724600

Physiology, Enkephalin.

Cullen JM and Cascella M (2022).
PubMed:
32491696

Physiology, Opioid Receptor.

Dhaliwal A and Gupta M (2022).
PubMed:
31536249

Biochemistry, Endogenous Opioids.

Shenoy SS and Lui F (2022).
PubMed:
30422494

Heroin Toxicity.

Oelhaf RC and Azadfard M (2022).
PubMed:
28613487

Opium Poppy (Papaver somniferum).

Chitty JA, Allen RS and Larkin PJ (2006).
Methods Mol Biol.
PubMed:
17033080

Buprenorphine: clinical pharmacokinetics in the treatment of opioid dependence.

Meta-Analysis
Elkader A and Sproule B (2005).
Clin Pharmacokinet.
PubMed:
15966752