Common Names: crato passionvine
A study investigated the effects of an ethanolic extract of the Brazilian passionflower plant on mice with a progressive model of Parkinson's disease induced by reserpine. Results showed that the treatment delayed the onset of motor impairments and prevented increased catalepsy behavior in the premotor phase, as well as the decrease in tyrosine hydroxylase immunostaining in the substantia nigra pars compacta. However, it did not modify reserpine-induced cognitive impairments. These findings suggest that the passionflower extract may have a neuroprotective effect on PD.