Common Names: purple passionflower
This study compared the effects of Passiflora incarnata and midazolam for controlling anxiety in patients undergoing surgery to remove their mandibular third molar. Anxiety is a common issue for dental patients during both minor and major procedures. Passiflora incarnata and midazolam were compared for their ability to reduce anxiety. The results demonstrated that Passiflora incarnata was equally effective at reducing anxiety as midazolam, but with fewer negative side effects. This suggests that natural remedies like Passiflora incarnata may be a feasible alternative to synthetic drugs for dental patients experiencing anxiety.
Study found PI may protect against injury after testicular torsion in rats. Could lead to new treatments for testicular injuries in humans.
Study tested Valeriana officinalis and Passiflora incarnata for anxiety and discomfort during extraction of two molars. Results can help improve patient experience during dental procedures.
Study: Investigated if Passiflora Incarnata (PI) protects against oxidative and inflammatory ovarian damage caused by ischemia-reperfusion (IR). Important for potential ovarian protection during medical procedures or conditions involving IR.
This study reviewed herbal medicines and phytochemicals for treating ADHD in children. It offers an updated analysis to aid in making informed decisions for pediatric ADHD treatment.
Passiflora extract reduces behavioral abnormalities and oxidative stress markers caused by prenatal VPA exposure, offering potential natural treatment for conditions like autism and ADHD.
Researchers conducted a systematic review of scientific articles published between 2010 and 2020 that evaluated the anxiolytic, sedative, and/or hypnotic effects of flower extracts in pre-clinical animal models. They found that some flower extracts have an anxiolytic effect comparable to diazepam, but their therapeutic utility in anxiety disorders needs more investigation. The study compiled the characteristics of anxiety studies in animal models, evaluated locomotor activity, and the hypnotic effect of the extracts. The study revealed that matricaria chamomilla had a sedative effect, and 23 other flower plants had anxiolytic effects. However, more reliable behavioral tests and better experimental designs are needed to obtain more conclusive evidence with clinical significance.
The study tested the effectiveness of a natural extract in reducing benzodiazepine misuse in depressed and anxious patients long-term treated with benzodiazepines. The study involved 186 patients, with half receiving the extract as an add-on treatment. The results showed a significantly higher rate of reduction in benzodiazepine dosage in the group receiving the extract, with complete discontinuation achieved at 1 and 3 months. This suggests the extract may be an effective add-on treatment during benzodiazepine tapering. Further studies are needed to investigate its potential in managing this important health issue.
Research has revealed potential herbal medicines for treating mild mood disorders, but with unclear active components. The microbiota-gut-brain axis offers new avenues for treatment and prevention of mood disorders.
COVID-19 can cause neurological complications, including anxiety, depression, MAD, and irreversible dementia, which can harm respiratory, circulatory, and heart function. Clinical trials suggest that phytotherapy, using natural plant materials like valeranon and apigenin, can aid these conditions. The study presents plant materials and their active compounds that can reduce post-COVID-19 complications, particularly those impacting the nervous system.
Chrysin, a natural molecule found in plants, has various health benefits such as antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and anti-apoptotic effects. Researchers have found that chrysin also exhibits anxiolytic and antidepressant-like effects through its interaction with neurotransmitter systems, particularly the GABAergic and serotonergic, and activation of neurotrophic factors. The antioxidant and anti-inflammatory activities of chrysin may also contribute to its therapeutic use for anxiety and depression disorders. These pre-clinical findings suggest that chrysin could be a promising novel therapy for these disorders.
Herbal medicines containing species have been used for anxiety treatment for centuries. This study investigated the uses of the main species of the genus with anxiolytic activity, secondary metabolites and pharmacological studies. Results indicate that species have health benefits, but clinical trials are still scarce. is the most studied species and the most used in natural anxiolytic herbal medicine formulations. However, there are hundreds of species potentially useful for medicinal and nutraceutical purposes that remain little explored. The complexity of extracts creates challenges for the development of herbal medicines.