Researchers isolated and studied a polysaccharide from a Chinese medicine fungus, finding it has antioxidant and antitumor properties by inhibiting cell proliferation and promoting apoptosis. This compound could be developed into a functional food.
Phellinus igniarius SY489 extract contains potent α-glucosidase inhibitors, including novel compounds, with potential as anti-diabetic drugs. Study suggests they interact with enzyme via mixed-type mechanism for promising drug development.
Medicinal fungus P. igniarius improves blood glucose, cholesterol, and triglyceride levels in rats, possibly by affecting metabolic pathways. Potential treatment for type 2 diabetes.
PA, an active compound from Phellinus igniarius, protects against cerebral ischemic injury by restoring mitochondrial function and reducing ER stress in both in vitro and in vivo models. This suggests PA could be a novel therapeutic agent for ischemic stroke.
Study identified key genes associated with increased mycelial production in mutant Phellinus igniarius JQ9, potentially improving production of bioactive compounds. Important for understanding and optimizing fungal fermentation processes in biotechnology and medicine.
The study compared the polysaccharide contents of four strains and found that QB72 had higher production and better antioxidant and antidiabetic activities. Hot water extracts of QB72 showed potential as α-amylase inhibitors in food and medication.
Researchers created a dihydromyricetin-loaded hydrogel called PCD, which has antioxidant and anti-inflammatory properties. PCD promotes wound healing, showing potential to treat diabetic wounds.
Ultrasound can enhance bio-compound production by altering cell morphology, structure, and organelles. Flavonoid content and production increased significantly under specific ultrasound conditions compared to untreated fermentation.
Researchers found that polysaccharides improved hyperglycemia symptoms, restored gut microbiota balance, and altered metabolic pathways in mice with type 2 diabetes, suggesting potential benefits for diabetes management.