Phellodendron chinense

Ethnobotanical Studies

Studies

Current development and structure-activity relationship study of berberine derivatives.

Review
Luo XF et al (2024).
Bioorg Med Chem.
DOI:
10.1016/j.bmc.2024.117880
PubMed:
39216382

Combining untargeted and targeted metabolomics to reveal the mechanisms of herb pair Anemarrhena asphodeloides Bunge and Phellodendron chinense C. K. Schneid on benign prostatic hyperplasia.

Wang S et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118539
PubMed:
38986754

Integrated network pharmacology and serum metabonomics analysis to explore the potential mechanism of Anemarrhena asphodeloides Bunge-Phellodendron chinense Schneid herb pair in the treatment of benign prostatic hyperplasia.

Cheng C et al (2024).
J Pharm Biomed Anal.
DOI:
10.1016/j.jpba.2024.116264
PubMed:
38889577

Comparative study of urea-(15)N fate in pure bamboo and bamboo-broadleaf mixed forests.

Wu Y et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1382934
PubMed:
38835866

Phellodendron chinense C.K.Schneid: an in vitro study on its anti-Helicobacter pylori effect.

Chen M et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118396
PubMed:
38823658

Study on anti-inflammatory effect of Shangkehuangshui in vitro and in vivo based on TLR4/TLR2-NF-κB signaling pathway.

Summary

Shangkehuangshui is a traditional Chinese medicine used for treating injuries. Despite its effectiveness, we still don't know how it works.

Immunology
Zhang B et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117709
PubMed:
38181931

The response of nutrient cycle, microbial community abundance and metabolic function to nitrogen fertilizer in rhizosphere soil of Phellodendron chinense Schneid seedlings.

Gu Y et al (2023).
Front Microbiol.
DOI:
10.3389/fmicb.2023.1302775
PubMed:
38173676

Integrated Transcriptomic and Metabolomic Analysis Reveals the Mechanism of Gibberillic acid Regulates the Growth and Flavonoid Synthesis in Phellodendron chinense Schneid Seedlings.

Phytochemistry
Yang L et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242216045
PubMed:
38003235

[Discovery, isolation and structural identification of alkaloid glycosides in six traditional Chinese medicine such as Coptis chinensis].

Summary

UPLC-QTOF-MS/MS identified 42 alkaloid glycosides, including two potentially new compounds, in traditional Chinese medicines. This aids in understanding their chemical composition and isolating alkaloid glycosides in other herbal medicines.

Phytochemistry
Wang R et al (2023).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20230518.301
PubMed:
37802799

Separation and purification of alkaloids and phenolic acids from Phellodendron chinense by pH-zone refining and online-storage inner-recycling counter-current chromatography.

Summary

This study separated and purified eight compounds from Phellodendron chinense using different chromatography techniques. The purified compounds include six alkaloids and two phenolic acids. Purity of the compounds was over 95.0%.

Phytochemistry
Zhu H et al (2023).
J Sep Sci.
DOI:
10.1002/jssc.202300497
PubMed:
37737621

Effect of heat-clearing and dampness-eliminating Chinese medicine for high-risk cervical cancer papillomavirus infection: a systematic review and meta-analysis of randomized controlled trials.

Summary

A study conducted a comprehensive review to evaluate the effectiveness and safety of heat-clearing and dampness-eliminating Chinese medicine (HDCM) for high-risk cervical HPV-infected patients. This information is important for making informed decisions about treating cervical HPV infections using HDCM.

Cancer
Huang S et al (2023).
Front Med (Lausanne).
DOI:
10.3389/fmed.2023.1022030
PubMed:
37692777

Study on chemical constituents and fingerprints of Phellodendron amurense Rupr. based on ultra-performance liquid chromatography-quadrupole-time-of-flight-mass spectrometry.

Phytochemistry
Feng Y et al (2023).
J Sep Sci.
DOI:
10.1002/jssc.202300151
PubMed:
37449326

Topical Chinese herbal medicine in treating atopic dermatitis (eczema): A systematic review and meta-analysis with core herbs exploration.

Dermatology
Wang MC et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116790
PubMed:
37328084

Chinese Herbal Medicine Improved Survival in Stage IV Breast Cancer Patients: Data Mining of the Incorporated Taiwan Cancer Registry Database and Hospital Database.

Summary

This study explores the relationship between traditional Chinese herbal medicine (CHM) and the survival rate in breast cancer patients, specifically those diagnosed with stage IV. While CHM has shown promise in improving survival rates and quality of life for metastatic cancer patients, little research has been done on its effects in stage IV breast cancer. This research aims to fill that gap and contribute to the growing field of personalized medicine by examining the association between CHM and survival rates in different stages of breast cancer.

Cancer
Chen PE et al (2023).
Integr Cancer Ther.
DOI:
10.1177/15347354231178898
PubMed:
37278256

Differences and biocontrol potential of haustorial endophytic fungi from Taxillus Chinensis on different host plants.

Song LS et al (2023).
BMC Microbiol.
DOI:
10.1186/s12866-023-02878-x
PubMed:
37173641

Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.

Summary

This study explored the potential neuroprotective effects of berberine (BBR) against Alzheimer's disease (AD) in vitro. Researchers established an apoptotic model in HT22 cells induced by Aβ and treated them with BBR. Results showed that BBR improved cell viability, inhibited Aβ-induced apoptosis and intracellular ROS levels, and intensified the activity of Nrf2/HO-1 antioxidants in HT22 cells. It also restrained the mitochondrial pathway of cellular apoptosis by decreasing the rate of p-p65/p65, cytochrome C, and cleaved caspase-3. This led the researchers to conclude that BBR provides neuroprotectiveness by alleviating oxidative stress and inhibiting the mitochondrial pathway of cellular apoptosis.

Neuroscience
Zhang RL et al (2023).
Bioorg Chem.
DOI:
10.1016/j.bioorg.2022.106210
PubMed:
36724611

Investigation of Asian Dyes and Pigments from the Artifact of "Murongzhi" and the Silk Road in China.

Wei Y et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.2c06572
PubMed:
36687087

In vitro tests to evaluate embryotoxicity and irritation of Chinese herbal medicine (Pentaherbs formulation) for atopic dermatitis.

Dermatology
Li L et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116149
PubMed:
36632857

Network pharmacology, molecular docking, and experimental pharmacology explored Ermiao wan protected against periodontitis via the PI3K/AKT and NF-κB/MAPK signal pathways.

Xia Z, Li Q and Tang Z (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115900
PubMed:
36414214

Compatibility between cold-natured medicine CP and hot-natured medicine AZ synergistically mitigates colitis mice through attenuating inflammation and restoring gut barrier.

Immunology
Li YY et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115902
PubMed:
36395977

Famous traditional Mongolian medicine Xieriga-4 (Turmeric-4) decoction: A review.

Review
Dulan et al (2022).
Chin Herb Med.
DOI:
10.1016/j.chmed.2022.05.002
PubMed:
36118011

Direct infusion electrospray ionization-ion mobility-mass spectrometry for rapid metabolite marker discovery of medicinal Phellodendron Bark.

Wen SS et al (2022).
J Pharm Biomed Anal.
DOI:
10.1016/j.jpba.2022.114939
PubMed:
35908412

Oxyberberine, a novel HO-1 agonist, effectively ameliorates oxidative stress and inflammatory response in LPS/D-GalN induced acute liver injury mice via coactivating erythrocyte metabolism and Nrf2 signaling pathway.

Immunology
Ai G et al (2022).
Food Chem Toxicol.
DOI:
10.1016/j.fct.2022.113215
PubMed:
35691465

Structural elucidation and anti-diabetic osteoporotic activity of an arabinogalactan from Phellodendron chinense Schneid.

Diabetes
Wang N et al (2021).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2021.118438
PubMed:
34364577

Berberine for bone regeneration: Therapeutic potential and molecular mechanisms.

Review
Zhang Y, Ma J and Zhang W (2021).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2021.114249
PubMed:
34058315

Jatrorrhizine: a review of its pharmacological effects.

Review
Rolle J et al (2021).
J Pharm Pharmacol.
DOI:
10.1093/jpp/rgaa065
PubMed:
33822109

The complete chloroplast genome of Phellodendron chinense (Rutaceae), an Endangered medicinal plant in southern China.

Genetics
Yang N, Liu Q and Zhao L (2020).
Mitochondrial DNA B Resour.
DOI:
10.1080/23802359.2020.1837688
PubMed:
33367103

Six New Methyl Apiofuranosides from the Bark of Phellodendron chinense Schneid and Their Inhibitory Effects on Nitric Oxide Production.

Wang PF et al (2019).
Molecules.
DOI:
10.3390/molecules24101851
PubMed:
31091775

Phellodendron chinense Schneid: A novel yellow-emitting luminescent material for white light-emitting diodes.

Lin PC et al (2017).
Sci Rep.
DOI:
10.1038/s41598-017-09291-1
PubMed:
28827629

Phytochemical Quantification and the In Vitro Acetylcholinesterase Inhibitory Activity of Phellodendron chinense and Its Components.

Summary

In this study, researchers analyzed the components of the dried bark of Phellodendron chinense and found it contains phellodendrine and berberine. They tested these components for their potential use in treating Alzheimer's disease and found they both inhibited the activity of acetylcholinesterase, an enzyme involved in the disease. Additionally, the bark extract and phellodendrine had antioxidant properties and protected brain cells from oxidative damage. While neither component had an effect on the beta-amyloid protein associated with Alzheimer's, this research suggests that Phellodendron chinense has potential as an anti-Alzheimer's agent.

NeurosciencePhytochemistry
Kim YJ et al (2017).
Molecules.
DOI:
10.3390/molecules22060925
PubMed:
28574473

4,8-Dimeth-oxy-furo[2,3-b]quinoline (γ-fagarine).

Liu Y, Wei K and Yang J (2011).
Acta Crystallogr Sect E Struct Rep Online.
DOI:
10.1107/S1600536811025062
PubMed:
22090957