Common Names: carry me seed
Scientists studied plants from the Phyllanthus genus for potential cancer treatments. They identified bioactive compounds using advanced analytical techniques and found promising results, suggesting the potential for future drug development. This research highlights the importance of natural products in cancer therapy.
Study evaluated storage effects on Schumach and Linn oil quality. Oils contain beneficial phytochemicals, lower rancidity, and inhibit enzymes linked to diabetes and oxidative stress. Consider incorporating these oils into your diet for health benefits.
This study explored the effects of Phyllanthus amarus extract on Paraquat-induced neurotoxicity in rats. The findings may be relevant for managing and treating neurological damage caused by environmental toxins.
This study found that including Moringa oleifera, Phyllanthus amarus, and Viscum album leaf meal in the diet of weaned female rabbits can reduce the negative effects of heat stress. These herbal inclusions improve antioxidant activity, lower lipid peroxidation, and suppress inflammation in rabbits.
Phyllanthus plants contain various compounds with potential antioxidant, anti-inflammatory, analgesic, antiulcer, antiviral, antitumor, and other health benefits. Docking experiments were performed to assess their potential activities against specific proteins. The results were compared to benchmark drugs ritonavir and ampicillin.
A study discovered that APALE, derived from Phyllanthus amarus, can protect against neurotoxicity caused by PDc. It improves cognitive function, regulates antioxidants and GABA levels, and reduces neuroinflammation, suggesting its potential as a neurotoxicity treatment.
Researchers studied the potential for a plant extract to inhibit acetylcholinesterase, an important target for Alzheimer's disease treatment. They conducted in vitro testing and molecular docking studies, identifying certain compounds as potential inhibitors. Further simulations confirmed these potential hits. The plant extract and identified compounds show promise for further study in developing Alzheimer's treatments.
Geraniin, a polyphenol, was studied for its potential to protect against cerebral ischemia/reperfusion (I/R) injury. The study used both in vivo and in vitro models to evaluate the neuroprotective effect of geraniin. Geraniin showed a significant reduction in infarct volume, decreased neurological deficit scores, and reduced cell apoptosis. It also increased the activity of superoxide dismutase (SOD) and decreased the activity of lactate dehydrogenase (LDH) and malondialdehyde (MDA), suggesting its antioxidant capacity. Additionally, geraniin increased Nrf2/HO-1 protein expression in vivo and in vitro, indicating an association with the protective effect against I/R injury. Geraniin shows promise as a potential treatment for ischemic stroke.
Researchers investigated the effect of alkaloid extracts from and leaves on aluminum-induced toxicity in fruit flies. The flies were exposed to aluminum and the extracts, then assessed for learning, memory, and movement. The results suggest that the alkaloids improved behavioral and biochemical impairments caused by aluminum toxicity. Amaryllidaceae alkaloids, caffeine, and carpaine were found in the extracts. These findings indicate that alkaloid extracts from these leaves could potentially be used to manage neurodegenerative diseases.