Phyllodium pulchellum

Ethnobotanical Studies

Studies

Effect of Alkaloids Isolated from Phyllodium pulchellum on Monoamine Levels and Monoamine Oxidase Activity in Rat Brain.

Summary

Researchers investigated the effects of alkaloids isolated from the roots of the medicinal plant Phyllodium pulchellum on neurotransmitter levels and monoamine oxidase (MAO) activity. Six alkaloids were identified, and after treatment with the alkaloids, a reduction in dopamine and serotonin levels in the rat brain was observed. The alkaloids inhibited MAO activity, suggesting potential therapeutic use as MAO inhibitors. Acute toxicity testing showed the plant extract was nontoxic. Further research may explore the potential of P. pulchellum alkaloids as treatment for conditions such as depression and Parkinson's disease.

Cai L et al (2016).
Evid Based Complement Alternat Med.
PubMed:
27195015

[Chemical constituents against hepatic fibrosis from Phyllodium pulchellum roots].

Wang C et al (2014).
Zhong Yao Cai.
PubMed:
25174106

Cinnamylphenols from Phyllodium pulchellum.

Shen CC et al (2005).
J Nat Prod.
PubMed:
15921433