Picrorhiza kurroa

Ethnobotanical Studies

Studies

Treating chronic atrophic gastritis: identifying sub-population based on real-world TCM electronic medical records.

Wang YM et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1444733
PubMed:
39170704

Androsin alleviates non-alcoholic fatty liver disease by activating autophagy and attenuating de novo lipogenesis.

Singh A et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155702
PubMed:
38749344

In vitro study on anti-proliferative and anti-cancer activity of picrosides in triple-negative breast cancer.

Cancer
Soni D, Wahi D and Verma S (2024).
Med Oncol.
DOI:
10.1007/s12032-024-02397-3
PubMed:
38717628

Nanoencapsulation of apocynin and vanillic acid extracted from Picrorhiza kurroa Royle ex Benth plant roots and its characterisation.

Manasa V et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e26156
PubMed:
38390167

A network pharmacology, molecular docking and in vitro investigation of Picrorhiza kurroa extract for the treatment of diabetic nephropathy.

Summary

A study investigated the potential of Royle ex Benth. (PK/Kutki) herb for the treatment of diabetic nephropathy. Network pharmacology and molecular docking were used to identify bioactive compounds, targets, and pathways involved. The herb showed promising effects on DN, suggesting its potential as a treatment option.

Diabetes
Pal S et al (2024).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2024.2314259
PubMed:
38356141

A randomized, placebo controlled, double blinded, parallel group clinical study to evaluate the efficacy and safety of AEV01 along with standard care for elderly patients with mild COVID-19.

Summary

Researchers conducted a study on medicinal plants for COVID-19 treatment and found promising results. Medicinal plants have benefits like better tolerability, compatibility with the human body, and fewer side effects, making them important for healthcare in both developing and developed countries.

COVID-19
Balan AK et al (2024).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2023.100860
PubMed:
38320447

Functional trait correlation network and proteomic analysis reveal multifactorial adaptation mechanisms to a climatic gradient associated with high altitude in the Himalayan region.

Kumari M and Kumar R (2024).
Plant Cell Environ.
DOI:
10.1111/pce.14830
PubMed:
38268334

Ethnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality control, conservation status and future prospective.

Summary

This review provides updated information on thirteen medicinal plants prioritized by the Indian government. It covers traditional uses, phytochemistry, pharmacology, quality control, and conservation status. Useful for understanding their importance and developing conservation strategies.

Review Phytochemistry
Anmol et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117385
PubMed:
37951375

In Vitro Antioxidant and Inhibitory Study of Picrorhiza kurroa (Kutki), Syzygium aromaticum (Loung), Lawsonia inermis (Henna), Rheum emodi (Revand Chini), Curcuma longa (Haldi) Against Lipid Per-Oxidation in Mice Brain and Liver.

Summary

This study evaluated the antioxidant and protective properties of certain medicinal plants against oxidative stress in the brain and liver. , , and showed strong effects and could potentially help manage or prevent degenerative diseases.

ImmunologyNeuroscience
Hassan F et al (2023).
Dose Response.
DOI:
10.1177/15593258231210431
PubMed:
37900620

Evaluation of Ayush-64 (a Polyherbal Formulation) and Its Ingredients in the Syrian Hamster Model for SARS-CoV-2 Infection Reveals the Preventative Potential of Alstonia scholaris.

Summary

Ayush-64, a herbal formulation, showed positive results in hamsters against COVID-19, preventing weight loss, reducing inflammation, and lung damage. Further research is needed to identify active compounds for future studies.

COVID-19
Rizvi ZA et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16091333
PubMed:
37765142

Efficacy and Safety of Add-On Plant-Based Drugs for COVID-19 Patients: A Review of the Randomized Control Trials.

Summary

Review finds that plant-based drugs, particularly herbs, used as add-on therapy for COVID-19 show efficacy and safety, potentially enhancing the immune system for treating the virus. (37 words)

Review COVID-19
Diantini A, Febriyanti RM and Levita J (2023).
Infect Drug Resist.
DOI:
10.2147/IDR.S417727
PubMed:
37361940

Global uses of traditional herbs for hepatic diseases and other pharmacological actions: A comprehensive review.

Review
Choudhary A et al (2023).
Polim Med.
DOI:
10.17219/pim/165977
PubMed:
37260126

Hepatoprotective Principles from the Rhizomes of Picrorhiza kurroa.

Sakamoto Y et al (2023).
Biol Pharm Bull.
DOI:
10.1248/bpb.b23-00167
PubMed:
37258151

Recent insights into the hepatoprotective potential of medicinal plants and plant-derived compounds.

Review
Thilagavathi R et al (2023).
Phytother Res.
DOI:
10.1002/ptr.7821
PubMed:
37022281

Pharmacological and Clinical Efficacy of Picrorhiza kurroa and Its Secondary Metabolites: A Comprehensive Review.

Review
Almeleebia TM, Alsayari A and Wahab S (2022).
Molecules.
DOI:
10.3390/molecules27238316
PubMed:
36500409

Biological Activity of Picrorhiza kurroa: A Source of Potential Antimicrobial Compounds against Yersinia enterocolitica.

Antimicrobial
Thapa A et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms232214090
PubMed:
36430568

The Use of Herbal Medicine in the Treatment of Vitiligo: An Updated Review.

Dermatology
Castillo E, González-Rosende ME and Martínez-Solís I (2022).
Planta Med.
DOI:
10.1055/a-1855-1839
PubMed:
36379447

A Comparative Study on Clinical Evaluation of the Hypolipidemic Effects of Allium sativum, Trigonella foenum-graecum, Commiphora mukul, Picrorhiza kurroa, and Piper nigrum: A Pilot Study.

Shaikh RF et al (2022).
Cureus.
DOI:
10.7759/cureus.26597
PubMed:
35936152

Author Correction: Growth Kinetics, Metabolites Production and Expression Profiling of Picrosides Biosynthetic Pathway Genes in Friable Callus Culture of Picrorhiza kurroa Royle ex Benth.

Genetics
Partap M et al (2022).
Appl Biochem Biotechnol.
DOI:
10.1007/s12010-021-03638-1
PubMed:
35877002

ABC transporters mined through comparative transcriptomics associate with organ-specific accumulation of picrosides in a medicinal herb, Picrorhiza kurroa.

Genetics
Pandey R et al (2023).
Protoplasma.
DOI:
10.1007/s00709-022-01786-7
PubMed:
35767110

Kutkin, iridoid glycosides enriched fraction of Picrorrhiza kurroa promotes insulin sensitivity and enhances glucose uptake by activating PI3K/Akt signaling in 3T3-L1 adipocytes.

Phytochemistry
Sinha K et al (2022).
Phytomedicine.
DOI:
10.1016/j.phymed.2022.154204
PubMed:
35671635

Picrorhiza kurroa, Royle ex Benth:Traditional uses, phytopharmacology, and translational potential in therapy of fatty liver disease.

Review
Raut A et al (2022).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2022.100558
PubMed:
35659739

Capturing acyltransferase(s) transforming final step in the biosynthesis of a major Iridoid Glycoside, (Picroside-II) in a Himalayan Medicinal Herb, Picrorhiza kurroa.

Phytochemistry
Kharb A et al (2022).
Mol Biol Rep.
DOI:
10.1007/s11033-022-07489-9
PubMed:
35581509