Pinellia ternata

Common Names: crowdipper

Ethnobotanical Studies

Studies

Comparative transcriptome analysis reveals defense responses against soft rot induced by Pectobacterium aroidearum and Pectobacterium carotovorum in Pinellia ternata.

Luo M et al (2024).
BMC Genomics.
PubMed:
39227779

Phylogeography of a herbal Pinellia ternata reveals repeated range expansions and inter/postglacial recolonization routes on the fragmented distribution pattern in China.

Jiang C et al (2024).
Ecol Evol.
PubMed:
39219572

Molecular quantification of herbs (Herb-Q): a pyrosequencing-based approach and its application in Pinellia ternata.

Pei Y et al (2024).
Chin J Nat Med.
PubMed:
39059835

Integrated network pharmacology and metabolomics to reveal the mechanism of Pinellia ternata inhibiting non-small cell lung cancer cells.

Feng F et al (2024).
BMC Complement Med Ther.
PubMed:
38992647

Mechanism of action of the Banxia-Xiakucao herb pair in sleep deprivation: New comprehensive evidence from network pharmacology, transcriptomics and molecular biology experiments.

Zhang ZY et al (2024).
J Ethnopharmacol.
PubMed:
38986753

Exploring the mechanism of luteolin improving immune and inflammatory responses in systemic sclerosis based on systems biology and cell experiments.

Ding X et al (2024).
Int Immunopharmacol.
PubMed:
38972211

Endogenous Hormone Levels and Transcriptomic Analysis Reveal the Mechanisms of Bulbil Initiation in Pinellia ternata.

Summary

Scientists studied the mechanisms of bulbil initiation in a medicinal plant, uncovering the role of hormones and genes. Understanding this process could improve molecular breeding techniques for this valuable species.

Mou L et al (2024).
Int J Mol Sci.
PubMed:
38892337

PtWRKY2, a WRKY transcription factor from Pinellia ternata confers heat tolerance in Arabidopsis.

Liu D et al (2024).
Sci Rep.
PubMed:
38877055

Organic fertilizer application promotes the soil nitrogen cycle and plant starch and sucrose metabolism to improve the yield of Pinellia ternata.

Wei L et al (2024).
Sci Rep.
PubMed:
38830940

The Polysaccharides from Pinellia ternata and Their Derivatives: Preparation, Structure Characteristics, and Activities inVitro.

Zhao X et al (2024).
Chem Biodivers.
PubMed:
38804585

A Chinese classical prescription Maimendong decoction in treatment of pulmonary fibrosis: an overview.

Review
Lao Q et al (2024).
Front Pharmacol.
PubMed:
38783956

Da-Chai-Hu-Tang Formula inhibits the progression and metastasis in HepG2 cells through modulation of the PI3K/AKT/STAT3-induced cell cycle arrest and apoptosis.

Duan ZW et al (2024).
J Ethnopharmacol.
PubMed:
38705430

Transcriptomic and metabolomic profiling provide insight into the role of sugars and hormones in leaf senescence of Pinellia ternata.

Chen J et al (2024).
Plant Cell Rep.
PubMed:
38647720

Investigation of the drug-drug interaction and incompatibility mechanism between Aconitum carmichaelii Debx and Pinellia ternata (Thunb.) Breit.

Ge M et al (2024).
J Ethnopharmacol.
PubMed:
38636577

Jiawei Dachaihu decoction protects against mitochondrial dysfunction in atherosclerosis (AS) mice with chronic unpredictable mild stress (CUMS) via SIRT1/PGC-1α/TFAM/LON signaling pathway.

Shi H et al (2024).
J Ethnopharmacol.
PubMed:
38631487

Correction: Heating or ginger extract reduces the content of Pinellia ternata lectin in the raphides of Pinellia tuber.

Liu Y et al (2024).
J Nat Med.
PubMed:
38568472

Brassinolide as potential rescue agent for Pinellia ternata grown under microplastic condition: Insights into their modulatory role on photosynthesis, redox homeostasis, and AsA-GSH cycling.

Zhang D et al (2024).
J Hazard Mater.
PubMed:
38547753

Comprehensive in silico characterization of NAC transcription factor family of Pinellia ternata and functional analysis of PtNAC66 under high-temperature tolerance in transgenic Arabidopsis thaliana.

Bo C et al (2024).
Plant Physiol Biochem.
PubMed:
38513515

Banxia-Shengjiang drug pair inhibits gastric cancer development and progression by improving body immunity.

Summary

Researchers used network pharmacology to study the Banxia-Shengjiang drug pair's effect on gastric cancer. They identified key target genes like PTGS2 and MMP9, which could be important for inhibiting GC through immune modulation. This study provides insights for potential therapeutic strategies in GC treatment.

Yang Y et al (2024).
Medicine (Baltimore).
PubMed:
38457601

Herbal medicine for the prevention of chemotherapy-induced nausea and vomiting in patients with advanced colorectal cancer: A prospective randomized controlled trial.

Summary

Researchers investigated the use of Hezhong granules, a Chinese herbal medicine, for managing chemotherapy-induced nausea and vomiting (CINV). Although the key components of the granules show promising antiemetic and antitumor properties, there is a need for scientifically designed clinical trials to validate their efficacy and safety.

Wu Z et al (2024).
J Ethnopharmacol.
PubMed:
38341113

Unveiling terahertz wave stress effects and mechanisms in Pinellia ternata: Challenges, insights, and future directions.

Review
Wang D et al (2024).
Physiol Plant.
PubMed:
38332400

Assembly and comparative analysis of the complete mitochondrial genome of Pinellia ternata.

Liu X et al (2024).
Funct Plant Biol.
PubMed:
38316513

Waterlogging faced by bulbil expansion improved the growth of Pinellia ternata and its effect reinforced by brassinolide.

Wu D et al (2024).
Plant Physiol Biochem.
PubMed:
38271862

Correction to: Identification of potentially suitable areas for nucleosides of Pinellia Ternata (Thunb.) Breit using ecological niche modeling.

Qiu J et al (2024).
Environ Monit Assess.
PubMed:
38243133

[Comprehensive evaluation of Pinellia ternata germplasm resources based on phenotypic trait classification].

Liu L et al (2023).
Zhongguo Zhong Yao Za Zhi.
PubMed:
38212021

Phytochemicals as estrogen receptor modulators?-a commentary of a network pharmacology study of two commonly employed Chinese herbal medicines in non-small cell lung cancer treatment.

Hereñú CB and Crespo R (2023).
Transl Cancer Res.
PubMed:
38197069

A review of the research progress on Pinellia ternata (Thunb.) Breit.: Botany, traditional uses, phytochemistry, pharmacology, toxicity and quality control.

Summary

The researchers investigated the medicinal properties of (Thunb.) Breit., a perennial herb used in traditional medicine. They discovered several potential benefits like anti-diarrhea, lipid-lowering, anti-tumor effects, making it worth exploring for medical applications.

Zou T et al (2023).
Heliyon.
PubMed:
38058630

Utilizing network pharmacology and experimental validation to explore the potential molecular mechanisms of raw Pinellia ternate in treating esophageal cancer.

Summary

Chinese medicine raw (RP) shows potential therapeutic benefits in treating esophageal cancer. This study used web-based pharmacological methods and cellular experiments to explore its effectiveness as a complementary approach to surgery and radiotherapy.

Liu Y et al (2023).
J Gastrointest Oncol.
PubMed:
37969842

Identification of potentially suitable areas for nucleosides of Pinellia Ternata (Thunb.) Breit using ecological niche modeling.

Qiu J et al (2023).
Environ Monit Assess.
PubMed:
37966553

Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.

Summary

Mai Men Dong decoction (MMDD), a traditional Chinese medicine, contains herbs known for treating respiratory conditions. Studying MMDD can enhance understanding and development of ethnopharmacology.

Shuangshuang HE et al (2023).
J Ethnopharmacol.
PubMed:
37865276

A novel Pinellia ternata catalase gene PtCAT2 regulates drought tolerance in Arabidopsis by modulating ROS balance.

Xu J et al (2023).
Front Plant Sci.
PubMed:
37849844

Responses of soil nutrients and rhizosphere microbial communities of a medicinal plant Pinelliaternata to vermicompost.

Zhang J et al (2023).
3 Biotech.
PubMed:
37810193

Transcriptome Analysis Reveals Long Non-Coding RNAs Involved in Shade-Induced Growth Promotion in Pinellia ternata.

Summary

Researchers investigated the growth response of plants to shading and its underlying mechanism. They focused on long non-coding RNAs (lncRNAs) which are crucial for growth and response to environmental conditions. Understanding this can enhance plant cultivation and adaptation.

Yang J et al (2023).
Front Biosci (Landmark Ed).
PubMed:
37796682

Corrigendum: Involvement of PtPHR1 in phosphates starvation-induced alkaloid biosynthesis in Pinellia ternata (Thunb.) Breit.

Summary

The researchers corrected an article with a specific DOI, suggesting a modification or update to the original article. You should care to ensure accurate and reliable information for making informed decisions in your lab.

Wang H et al (2023).
Front Plant Sci.
PubMed:
37794941

The Extract of Pinellia Ternata-Induced Apoptosis of Leukemia Cells by Regulating the Expression of Bax, Bcl-2 and Caspase-3 Protein Expression in Mice.

Summary

Pinellia ternata extract was tested on leukemia cells using various techniques. Results showed that the extract can decrease cell proliferation and promote apoptosis, making it a potential new therapy for leukemia.

Li ZF et al (2023).
Transplant Proc.
PubMed:
37777366

Analysis of the response mechanisms of Pinellia ternata to terahertz wave stresses using transcriptome and metabolic data.

Summary

Scientists investigated the effects of terahertz radiation (THZ) on the growth of (Thunb.) Breit., a medicinal plant. They found that THZ influenced the transcriptome and metabolome of the plants, leading to changes in growth and phytohormone levels. This study enhances our understanding of plant growth mechanisms.

Wang D et al (2023).
Front Plant Sci.
PubMed:
37771489

mRNA-Seq and miRNA-Seq Analyses Provide Insights into the Mechanism of Pinellia ternata Bulbil Initiation Induced by Phytohormones.

Xu W et al (2023).
Genes (Basel).
PubMed:
37761867

Stigmasterol and gastrodin, two major components of banxia-baizhu-tianma decoction, alleviated the excessive phlegm-dampness hypertension by reducing lipid accumulation.

Summary

Banxia baizhu tianma decoction (BBTD) is a traditional Chinese medicine with a long history of use for treating excessive phlegm-dampness hypertension. However, the specific effects of each herb in BBTD are unclear, limiting its full understanding and potential for hypertension treatment.

Zhang H et al (2023).
J Ethnopharmacol.
PubMed:
37726069

Establishment of protoplasts transient expression system in Pinellia ternata (Thunb.) Breit.

Tian YH et al (2023).
Biotechnol Lett.
PubMed:
37589824

Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining.

Summary

Lung cancer is a significant global health issue, resulting in a high number of deaths. It is particularly prevalent in China, requiring attention for prevention and treatment strategies.

Hong M et al (2023).
Technol Health Care.
PubMed:
37545275

Transcriptome Profiling Reveals Differential Gene Expression during the Process of Microtuber Formation in Pinellia ternata.

Bo C et al (2023).
Int J Mol Sci.
PubMed:
37511363

Integrated physicochemical, hormonal, and transcriptomic analysis reveals the underlying mechanism of callus formation in Pinellia ternata hydroponic cuttings.

Summary

Researchers developed a highly efficient cultivation technology for hydroponic cuttings of a medicinal herb. It increases seedling production rate and addresses issues in traditional cultivation methods. However, the callus formation mechanism in hydroponic cuttings is still unclear.

Duan X et al (2023).
Front Plant Sci.
PubMed:
37409296

Heating or ginger extract reduces the content of Pinellia ternata lectin in the raphides of Pinellia tuber.

Liu Y et al (2023).
J Nat Med.
PubMed:
37311896

Pinellia ternata (Thunb.) Breit. attenuates the allergic airway inflammation of cold asthma via inhibiting the activation of TLR4-medicated NF-kB and NLRP3 signaling pathway.

Summary

Pinellia ternata is effective against allergic airway inflammation, particularly in cold asthma, but its active ingredients and mechanism of action are still unclear.

Tao X et al (2023).
J Ethnopharmacol.
PubMed:
37268256

Integrative Analysis of Metabolomic and Transcriptomic Data Reveals the Mechanism of Color Formation in Corms of Pinellia ternata.

Xu R et al (2023).
Int J Mol Sci.
PubMed:
37175702

Physiological and transcriptional responses to heat stress in a typical phenotype of Pinellia ternata.

Wang J et al (2023).
Chin J Nat Med.
PubMed:
37120243

Pinellia ternata-containing traditional Chinese medicine combined with 5-HT3RAs for chemotherapy-induced nausea and vomiting: A PRISMA-compliant systematic review and meta-analysis of 22 RCTs.

Zhai X et al (2023).
Phytomedicine.
PubMed:
37099981

Preliminary exploration of method for screening efficacy markers compatibility in TCM prescriptions based on Q-markers: Anti-inflammatory activity of Dachaihu decoction as an example.

Bi S et al (2023).
J Ethnopharmacol.
PubMed:
37088240

Pinellia genus: A systematic review of active ingredients, pharmacological effects and action mechanism, toxicological evaluation, and multi-omics application.

Chen C et al (2023).
Gene.
PubMed:
37044184

Transcriptome analysis reveals important regulatory genes and pathways for tuber color variation in Pinellia ternata (Thunb.) Breit.

Yin C et al (2023).
Protoplasma.
PubMed:
36918417

Chitosan Spraying Enhances the Growth, Photosynthesis, and Resistance of Continuous Pinellia ternata and Promotes Its Yield and Quality.

Chen F et al (2023).
Molecules.
PubMed:
36903297

Integrated analysis of metabolome and transcriptome reveals key candidate genes involved in flavonoid biosynthesis in Pinellia ternata under heat stress.

Guo L et al (2023).
J Plant Res.
PubMed:
36881276

Bacillus cereus WL08 immobilized on tobacco stem charcoal eliminates butylated hydroxytoluene in soils and alleviates the continuous cropping obstacle of Pinellia ternata.

Zhang C et al (2023).
J Hazard Mater.
PubMed:
36870095

Diversity, antibacterial and phytotoxic activities of culturable endophytic fungi from Pinellia pedatisecta and Pinellia ternata.

Kong K et al (2023).
BMC Microbiol.
PubMed:
36707757

Efficacy and safety of traditional Chinese medicine for the treatment of epilepsy: A updated meta-analysis of randomized controlled trials.

Summary

This study evaluated Traditional Chinese Medicine (TCM) for treating epilepsy. The efficacy and safety of TCM were tested. Results showed that TCM was effective and safe in treating epilepsy. This suggests that TCM could be a potential alternative treatment option for epilepsy patients.

Meta-Analysis Neuroscience
Lu H et al (2023).
Epilepsy Res.
PubMed:
36603453

Intercropping of Pinellia ternata (herbal plant) with Sedum alfredii (Cd-hyperaccumulator) to reduce soil cadmium (Cd) absorption and improve yield.

Ng CWW et al (2023).
Environ Pollut.
PubMed:
36565916

Principal Component Analysis to Assess the Changes of Yield and Quality in Pinellia ternata at Different Stages after Brassinolide Treatments.

Guo C et al (2022).
Int J Mol Sci.
PubMed:
36499701

Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway: Integrating network pharmacology and experimental validation in vivo.

Zheng R et al (2023).
J Ethnopharmacol.
PubMed:
36273747

Raw Pinelliae Rhizoma: examination of sedative and hypnotic effects in mice and chemical analysis.

Lin S et al (2023).
Sleep Breath.
PubMed:
36166133

Processed product (Pinelliae Rhizoma Praeparatum) of Pinellia ternata (Thunb.) Breit. Alleviates the allergic airway inflammation of cold phlegm via regulation of PKC/EGFR/MAPK/PI3K-AKT signaling pathway.

Tao X et al (2022).
J Ethnopharmacol.
PubMed:
35688257

Identifying and characterizing Stagonosporopsis cucurbitacearum causing spot blight on Pinellia ternata in China.

Zhou J et al (2022).
PeerJ.
PubMed:
35437476

Utilizing network pharmacology and experimental validation to explore the potential molecular mechanisms of BanXia-YiYiRen in treating insomnia.

Wang L et al (2022).
Bioengineered.
PubMed:
35067174

UHPLC-MS-based metabolomic approach for the quality evaluation of Pinellia ternata tubers grown in shaded environments.

Xue T et al (2021).
J Nat Med.
PubMed:
34275105

Network Pharmacology and Molecular Docking Combined to Analyze the Molecular and Pharmacological Mechanism of Pinellia ternata in the Treatment of Hypertension.

Zhai Z et al (2021).
Curr Issues Mol Biol.
PubMed:
34062719

Pinellia ternata (Thunb.) Breit: A review of its germplasm resources, genetic diversity and active components.

Review Genetics
Mao R and He Z (2020).
J Ethnopharmacol.
PubMed:
32798614