Piper aduncum

Common Names: spiked pepper, higuillo de hoja menuda

Ethnobotanical Studies

Studies

Antileishmanial activity of a dillapiole derivative obtained from Piper aduncum L. (Piperaceae).

Barros AMC et al (2024).
Braz J Biol.
DOI:
10.1590/1519-6984.282198
PubMed:
39166687

Effects of Piper aduncum (Piperales: Piperaceae) Essential Oil and Its Main Component Dillapiole on Detoxifying Enzymes and Acetylcholinesterase Activity of Amblyomma sculptum (Acari: Ixodidae).

Summary

Study on acaricidal activity of essential oil and Dillapiole against tick larvae. Dillapiole more effective than EO. Increased enzyme activity in treated larvae. Potential natural acaricide development.

NeurosciencePhytochemistry
Pereira Filho AA et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25105420
PubMed:
38791458

UHPLC-HRMS/MS Chemical Fingerprinting of the Bioactive Partition from Cultivated Piper aduncum L.

de Luna AV et al (2024).
Molecules.
DOI:
10.3390/molecules29081690
PubMed:
38675510

PPAR gamma agonistic activity of dillapiole: protective effects against diabetic nephropathy.

Summary

Dillapiole, a component of essential oils, acts as a PPARγ agonist, improving glucose levels and lipid profiles in diabetic mice. Promising potential for further research on diabetes treatment.

Diabetes
Shafi S, Khurana N and Gupta J (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2334323
PubMed:
38563125

Modulation of Gut Microbiota, and Morphometry, Blood Profiles and performance of Broiler Chickens Supplemented with Piper aduncum, Morinda citrifolia, and Artocarpus altilis leaves Ethanolic Extracts.

Gastroenterology
Paredes-López DM et al (2024).
Front Vet Sci.
DOI:
10.3389/fvets.2024.1286152
PubMed:
38511194

In vitro anti-inflammatory activity of Plantago major L. and Piper aduncum L. on phospholipase A2 from the venom of snake Lachesis muta muta.

Immunology
Yarleque-Chocas M et al (2023).
Rev Peru Med Exp Salud Publica.
DOI:
10.17843/rpmesp.2023.403.12191
PubMed:
37991036

Synergism in Two-Component Insecticides with Dillapiole against Fall Armyworm.

Fazolin M et al (2023).
Plants (Basel).
DOI:
10.3390/plants12173042
PubMed:
37687289

Acute toxicity of essential oils of Aloysia triphylla (L'Hér.) Britton, Lippia gracilis Schauer, and Piper aduncum L. in Colossoma macropomum (Cuvier, 1818).

Santos PR et al (2023).
Braz J Biol.
DOI:
10.1590/1519-6984.272853
PubMed:
37672435

Insecticidal activity of essential oils from American native plants against Aedes aegypti (Diptera: Culicidae): an introduction to their possible mechanism of action.

Phytochemistry
Duque JE et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-30046-8
PubMed:
36805522

Piper aduncum Essential Oil Rich in Dillapiole: Development of Hydrogel-Thickened Nanoemulsion and Nanostructured Lipid Carrier Intended for Skin Delivery.

Phytochemistry
Carneiro SB et al (2022).
Pharmaceutics.
DOI:
10.3390/pharmaceutics14112525
PubMed:
36432716

Development, validation and application of a gas chromatography method for the determination of dillapiole from Piper aduncum essential oil in skin permeation samples.

Phytochemistry
Braga Carneiro S et al (2023).
Biomed Chromatogr.
DOI:
10.1002/bmc.5544
PubMed:
36342416

Antifungal Activity against Fusarium oxysporum of Botanical End-Products: An Integration of Chemical Composition and Antifungal Activity Datasets to Identify Antifungal Bioactives.

Antimicrobial
Cárdenas-Laverde D, Barbosa-Cornelio R and Coy-Barrera E (2021).
Plants (Basel).
DOI:
10.3390/plants10122563
PubMed:
34961034

Fumigant toxicity and biochemical effects of selected essential oils toward the red flour beetle, Tribolium castaneum (Coleoptera: Tenebrionidae).

Phytochemistry
Oviedo-Sarmiento JS et al (2021).
Pestic Biochem Physiol.
DOI:
10.1016/j.pestbp.2021.104941
PubMed:
34802531

Total syntheses of (+)-adunctins C and D: assignment of their absolute configurations.

Xiao J et al (2021).
Org Biomol Chem.
DOI:
10.1039/d1ob02055b
PubMed:
34748620

Genotoxic and mutagenic effects of methyl ether dillapiole on the development of Aedes aegypti (Diptera: Culicidae).

Genetics
da Silva JS et al (2021).
Med Vet Entomol.
DOI:
10.1111/mve.12533
PubMed:
34077571

Gas chromatography coupled to mass spectrometry (GC-MS) characterization and evaluation of antibacterial bioactivities of the essential oils from Piper arboreum Aubl., Piper aduncum L. e Piper gaudichaudianum Kunth.

Phytochemistry
da Silva ACA et al (2020).
Z Naturforsch C J Biosci.
DOI:
10.1515/znc-2020-0045
PubMed:
32673283

Antioxidant and Cytoprotective Effect of Piper aduncum L. against Sodium Fluoride (NaF)-Induced Toxicity in Albino Mice.

Herrera-Calderon O et al (2019).
Toxics.
DOI:
10.3390/toxics7020028
PubMed:
31100918

Encapsulation of Piper aduncum and Piper hispidinervum essential oils in gelatin nanoparticles: a possible sustainable control tool of Aedes aegypti, Tetranychus urticae and Cerataphis lataniae.

Phytochemistry
Silva LS et al (2019).
J Sci Food Agric.
DOI:
10.1002/jsfa.9233
PubMed:
29971785

Piper aduncum against Haemonchus contortus isolates: cross resistance and the research of natural bioactive compounds.

Gaínza YA et al (2016).
Rev Bras Parasitol Vet.
DOI:
10.1590/S1984-29612016073
PubMed:
27925067

Cardamonin, a schistosomicidal chalcone from Piper aduncum L. (Piperaceae) that inhibits Schistosoma mansoni ATP diphosphohydrolase.

de Castro CC et al (2015).
Phytomedicine.
DOI:
10.1016/j.phymed.2015.06.009
PubMed:
26321741

Evaluation of Piper aduncum Linn. Essential Oil (Fam:Piperaceae) against Periplaneta americana (L.).

Phytochemistry
Ling A I, Sulaiman S and Othman H (2009).
Iran J Arthropod Borne Dis.
PubMed:
22808375