Piper wallichii

Ethnobotanical Studies

Gongcheng County, Guangxi, China

Uses: Gout

DOI:: 10.1186/s13002-022-00544-6
PubMed:: 35729593

Gelao ethnic minority, North Guizhou, China

Uses: Rheumatic pain/lumbar and leg pain

DOI:: 10.3389/fphar.2023.1217599
PubMed:: 37719846

Studies

Targeting autophagy to discover the Piper wallichii petroleum ether fraction exhibiting antiaging and anti-Alzheimer's disease effects in Caenorhabditis elegans.

Summary

Scientists studied the effects of natural medicines on autophagy and aging-related Alzheimer's disease using Caenorhabditis elegans (C. elegans). They found that the incidence of Alzheimer's disease is increasing along with decreased autophagy activity due to population aging. Multiple C. elegans models were used to evaluate autophagy and investigate the potential therapeutic effects of natural medicine in antiaging and anti-AD effects. This research provides valuable insights into understanding and treating aging-related diseases.

Neuroscience

Zhu FD et al (2023).; Phytomedicine.
DOI:: 10.1016/j.phymed.2023.154916
PubMed:: 37327643

Ethanol extract of Piper wallichii ameliorates DSS-induced ulcerative colitis in mice: Involvement of TLR4/NF-κB/COX-2 signaling pathway.

Immunology

Zhao J et al (2023).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2023.116293
PubMed:: 36806346

Chemical constituents and antibacterial activity from the stems and leaves of Piper wallichii.

Nongmai C et al (2022).; J Asian Nat Prod Res.
DOI:: 10.1080/10286020.2021.1933959
PubMed:: 34085561

Wallichinine reverses ABCB1-mediated cancer multidrug resistance.

Cancer

Lv M et al (2016).; Am J Transl Res.
PubMed:: 27508017

Chemical constituents from Piper wallichii.

Shi YN et al (2015).; Nat Prod Res.
DOI:: 10.1080/14786419.2014.998217
PubMed:: 25573271

Lignans and aromatic glycosides from Piper wallichii and their antithrombotic activities.

Phytochemistry

Shi YN et al (2015).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2014.12.038
PubMed:: 25555357

[Identification of some Piper crude drugs based on Fourier transform infrared spectrometry].

Zhou Y et al (2014).; Guang Pu Xue Yu Guang Pu Fen Xi.
PubMed:: 25532337

A new flavonol C-glycoside and a rare bioactive lignanamide from Piper wallichii Miq. Hand.-Mazz.

Phytochemistry

Wang PP et al (2014).; Chin J Nat Med.
DOI:: 10.1016/S1875-5364(14)60047-9
PubMed:: 24856762

[Study on the bioactive constituents of Piper wallichii].

Zhao GW et al (2012).; Zhong Yao Cai.
PubMed:: 22734410

10.

[Neolignans and lignan from Piper wallichii].

Phytochemistry

Duan S, Zhang P and Yu P (2010).; Zhongguo Zhong Yao Za Zhi.
PubMed:: 20394289

11.

[Study on three aristololatams from Piper wallichii].

Zhao Y, Ruan J and Cai Y (2005).; Zhong Yao Cai.
PubMed:: 16107026

12.

[The isolation and identification of PAF inhibitors from Piper wallichii (Miq.) Hand-Mazz and P. hancei Maxim].

Han GQ et al (1989).; Yao Xue Xue Bao.
PubMed:: 2609983