Plantago asiatica

Ethnobotanical Studies

Gyirong Valley, Tibet, China

Uses: Medicine: hypertension, soaked in water; food: vegetable, cooked vegetable

DOI:: 10.1186/s13002-022-00565-1
PubMed:: 36401315

Gongcheng County, Guangxi, China

Uses: Stone, electric ophthalmia, bruise, furuncle, diarrhea, dysentery, nephritis edema, typhoid

DOI:: 10.1186/s13002-022-00544-6
PubMed:: 35729593

Bulang people, Yunnan, China

Uses: Urinary retention, leucorrhea, hematuria, cough, pharyngitis, heat clearing and detoxification

DOI:: 10.1186/s13002-023-00609+0
PubMed:: 37679773

Yi people, Mile, Yunnan, China

Uses: Cough, edema, eye disease

DOI:: 10.1186/s13002-024-00656-1
PubMed:: 38395900

Gaoligongshan area, Western Yunnan, Southwest China

Uses: clearing away heat andtoxic materials

DOI:: 10.1186/s13002-023-00638-9
PubMed:: 38225656

Studies

High-resolution X-ray computed tomography for identifying herbal medicines was as effective as microscopic examination.

Tokumoto H, Uchiyama N and Ito M (2024).; J Nat Med.
DOI:: 10.1007/s11418-024-01840-z
PubMed:: 39207580

Plantago asiatica seed as a protective agent for mitigating metals toxicity on Penaeusvannamei.

Liao ZH et al (2024).; Fish Shellfish Immunol.
DOI:: 10.1016/j.fsi.2024.109824
PubMed:: 39127393

Plantaginis Semen Ameliorates Hyperuricemia Induced by Potassium Oxonate.

Liu T et al (2024).; Int J Mol Sci.
DOI:: 10.3390/ijms25158548
PubMed:: 39126116

Development and evaluation of one-step RT-qPCR TaqMan multiplex panels applied to six viruses occurring in lily and tulip bulbs.

van Gent-Pelzer MPE et al (2024).; J Virol Methods.
DOI:: 10.1016/j.jviromet.2024.114987
PubMed:: 38901647

bZIP60 and Bax inhibitor 1 contribute IRE1-dependent and independent roles to potexvirus infection.

Adhikari B et al (2024).; New Phytol.
DOI:: 10.1111/nph.19882
PubMed:: 38853429

Plantaginis Semen ameliorates diabetic kidney disease via targeting the sphingosine kinase 1/sphingosine-1-phosphate pathway.

Summary

Researchers studied the medicinal properties of Plantaginis Semen (PS) in China for diuretic, anti-hypertensive, anti-hyperlipidemic, and anti-hyperglycemic effects. Limited research on its therapeutic mechanisms warrants further investigation.

Diabetes

Lan JP et al (2024).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2024.118221
PubMed:: 38677576

Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia.

Zhou H et al (2024).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2024.118068
PubMed:: 38513777

Local Application of Acibenzolar-S-Methyl Treatment Induces Antiviral Responses in Distal Leaves of Arabidopsis thaliana.

Summary

Scientists found that the synthetic analog of salicylic acid, acibenzolar-methyl (ASM), can suppress plantago asiatica mosaic virus (PlAMV) infection in distal leaves. This antiviral effect is mediated by the co-action of salicylic acid (SA) and -hydroxypipecolic acid (NHP), and can potentially be used to enhance plant defense against viral pathogens.

Antimicrobial

Ito S et al (2024).; Int J Mol Sci.
DOI:: 10.3390/ijms25031808
PubMed:: 38339085

Citrisorbicillinol, an undescribed hybrid sorbicillinoid with osteogenic activity from Penicillium citrinum ZY-2.

Zhang Y et al (2024).; Fitoterapia.
DOI:: 10.1016/j.fitote.2024.105836
PubMed:: 38286315

10.

Ultrasound-assisted ethanol/K(2) HPO(4) aqueous two-phase extraction of polysaccharides from Plantago asiatica L. seeds: Process optimization, physicochemical properties, and antioxidant activity.

Immunology Phytochemistry

Zhang H and Zhu W (2024).; Phytochem Anal.
DOI:: 10.1002/pca.3315
PubMed:: 38263361

11.

Establishment of Polydopamine-Modified HK-2 Cell Membrane Chromatography and Screening of Active Components from Plantago asiatica L.

Phytochemistry

Gao H et al (2024).; Int J Mol Sci.
DOI:: 10.3390/ijms25021153
PubMed:: 38256226

12.

Plantago asiatica L. polysaccharides: Physiochemical properties, structural characteristics, biological activity and application prospects: A review.

Review

Huan C et al (2023).; Int J Biol Macromol.
DOI:: 10.1016/j.ijbiomac.2023.128990
PubMed:: 38158057

13.

Long-term passages of Plantago asiatica mosaic virus alter virulence and multiplication in Nicotiana benthamiana plants.

Nakamura D et al (2023).; Arch Virol.
DOI:: 10.1007/s00705-023-05934-z
PubMed:: 38092981

14.

[Quality evaluation of Compound Cheqian Tablets based on UPLC-Q-TOF-MS/MS, network pharmacology and "double external standards" QAMS].

Wang K et al (2023).; Zhongguo Zhong Yao Za Zhi.
DOI:: 10.19540/j.cnki.cjcmm.20230605.302
PubMed:: 37802806

15.

The medicinal plant used in the Guangxi Fangcheng Golden Camellias national nature reserve, a coastal region in southern China.

Hu R et al (2023).; J Ethnobiol Ethnomed.
DOI:: 10.1186/s13002-023-00605-4
PubMed:: 37501198

16.

Sirt3 regulates NLRP3 and participates in the effects of plantainoside D on acute lung injury sepsis.

Wang J et al (2023).; Aging (Albany NY).
DOI:: 10.18632/aging.204628
PubMed:: 37494665

17.

Plantamajoside modulates immune dysregulation and hepatic lipid metabolism in rats with nonalcoholic fatty liver disease via AMPK/Nrf2 elevation.

Wu JM et al (2023).; Kaohsiung J Med Sci.
DOI:: 10.1002/kjm2.12712
PubMed:: 37265208

18.

Interaction of EXA1 and eIF4E Family Members Facilitates Potexvirus Infection in Arabidopsis thaliana.

Nishikawa M et al (2023).; J Virol.
DOI:: 10.1128/jvi.00221-23
PubMed:: 37199623

19.

Metabolites analysis of plantamajoside based on gut microbiota-drug interaction.

Gastroenterology

Xu H et al (2023).; Phytomedicine.
DOI:: 10.1016/j.phymed.2023.154841
PubMed:: 37196513

20.

The potential of Chinese medicines in the treatment of hyperuricemia.

Review

Tang J et al (2023).; Am J Transl Res.
PubMed:: 37193181

21.

Dynamin-related protein 2 interacts with the membrane-associated methyltransferase domain of plantago asiatica mosaic virus replicase and promotes viral replication.

Shinji H et al (2023).; Virus Res.
DOI:: 10.1016/j.virusres.2023.199128
PubMed:: 37149224

22.

Genetic diversity and phylogenetic characteristics of viruses in lily plants in Beijing.

Chen L et al (2023).; Front Microbiol.
DOI:: 10.3389/fmicb.2023.1127235
PubMed:: 37138632

23.

Ethnobotanical study on herbal tea drinks in Guangxi, China.

Ethnobotany

Long T et al (2023).; J Ethnobiol Ethnomed.
DOI:: 10.1186/s13002-023-00579-3
PubMed:: 37004116

24.

Effect of Plantago asiatica L. extract on the anagen phase in human hair follicle dermal papilla cells.

Lee J et al (2023).; J Cosmet Dermatol.
DOI:: 10.1111/jocd.15720
PubMed:: 36999450

25.

Study on the Mechanism of Qing-Fei-Shen-Shi Decoction on Asthma Based on Integrated 16S rRNA Sequencing and Untargeted Metabolomics.

Summary

QFSS, a Chinese herbal formula, showed promising results in treating asthma in mice by regulating gut microbiota and metabolism. Potential mechanism for further research.

Asthma Genetics

Hu H et al (2023).; Evid Based Complement Alternat Med.
DOI:: 10.1155/2023/1456844
PubMed:: 36846048

26.

Study on herb-herb interaction between active components of Plantago asiatica L. seed and Coptis chinensis Franch. rhizoma based on transporters using UHPLC-MS/MS.

Zhang J et al (2023).; J Pharm Biomed Anal.
DOI:: 10.1016/j.jpba.2023.115234
PubMed:: 36773541

27.

Plantainoside D Reduces Depolarization-Evoked Glutamate Release from Rat Cerebral Cortical Synaptosomes.

Chiu KM et al (2023).; Molecules.
DOI:: 10.3390/molecules28031313
PubMed:: 36770979

28.

Extraction, separation and kinetics of phenylethanosides from Plantago asiatica L. by an innovative extraction technology-deep eutectic solvent-based ultrasound-assisted extraction.

Feng C et al (2023).; Prep Biochem Biotechnol.
DOI:: 10.1080/10826068.2022.2163257
PubMed:: 36719813

29.

Polysaccharides of Plantago asiatica enhance antitumor activity via regulating macrophages to M1-like phenotype.

Cancer Immunology

Zhang J et al (2023).; Biomed Pharmacother.
DOI:: 10.1016/j.biopha.2023.114246
PubMed:: 36652734

30.

Comprehensive analysis of complete chloroplast genome sequence of Plantago asiatica L. (Plantaginaceae).

Genetics

Wu J et al (2023).; Plant Signal Behav.
DOI:: 10.1080/15592324.2022.2163345
PubMed:: 36592637

31.

Phytochemicals, Biological Activities, Molecular Mechanisms, and Future Prospects of Plantago asiatica L.

Review Phytochemistry

Wen SY et al (2023).; J Agric Food Chem.
DOI:: 10.1021/acs.jafc.2c07735
PubMed:: 36545763

32.

Development of a multiplex RT-PCR assay for simultaneous detection of Lily symptomless virus, Lily mottle virus, Cucumber mosaic virus, and Plantago asiatica mosaic virus in Lilies.

Xu L and Ming J (2022).; Virol J.
DOI:: 10.1186/s12985-022-01947-3
PubMed:: 36527114

33.

Anticoccidial activity of natural plants extracts mixture against Eimeria tenella: An in vitro and in vivo study.

Han M et al (2022).; Front Vet Sci.
DOI:: 10.3389/fvets.2022.1066543
PubMed:: 36504841

34.

Plantamajoside attenuates cardiac fibrosis via inhibiting AGEs activated-RAGE/autophagy/EndMT pathway.

Cardiology

Zhang L et al (2023).; Phytother Res.
DOI:: 10.1002/ptr.7663
PubMed:: 36349468

35.

Effects of cubic ecological restoration of mining wasteland and the preferred restoration scheme.

Liu J et al (2022).; Sci Total Environ.
DOI:: 10.1016/j.scitotenv.2022.158155
PubMed:: 35988610

36.

Plantago asiatica mosaic virus: An emerging plant virus causing necrosis in lilies and a new model RNA virus for molecular research.

Review Genetics

Komatsu K and Hammond J (2022).; Mol Plant Pathol.
DOI:: 10.1111/mpp.13243
PubMed:: 35856603

37.

Amino acid promotes selenium uptake in medicinal plant Plantago asiatica.

Liao R and Zhu J (2022).; Physiol Mol Biol Plants.
DOI:: 10.1007/s12298-022-01196-2
PubMed:: 35722512

38.

Complete chloroplast genome of Plantago asiatica and its phylogenetic position in Plantaginaceae.

Genetics

Si H et al (2022).; Mitochondrial DNA B Resour.
DOI:: 10.1080/23802359.2022.2073838
PubMed:: 35573592

39.

Effects of indirect plant-plant interaction via root exudate on growth and leaf chemical contents in Rumex obtusifolius.

Ohsaki H and Yamawo A (2022).; Plant Signal Behav.
DOI:: 10.1080/15592324.2022.2050628
PubMed:: 35318884

40.

Antiviral Activity of Plantago asiatica Polysaccharide against Pseudorabies Virus In Vitro.

Antimicrobial

Huan C et al (2022).; Oxid Med Cell Longev.
DOI:: 10.1155/2022/3570475
PubMed:: 35096266

41.

Complete genome sequence of Plantago asiatica virus A, a novel putative member of the genus Polerovirus.

Genetics

Igori D et al (2022).; Arch Virol.
DOI:: 10.1007/s00705-021-05265-x
PubMed:: 34636954

42.

Plantago asiatica L. seeds extract protects against cardiomyocyte injury in isoproterenol- induced cardiac hypertrophy by inhibiting excessive autophagy and apoptosis in mice.

Cardiology

Fan W et al (2021).; Phytomedicine.
DOI:: 10.1016/j.phymed.2021.153681
PubMed:: 34371252

43.

Targeted Isolation of Antioxidant Constituents from Plantago asiatica L. and In Vitro Activity Assay.

Dong Y et al (2020).; Molecules.
DOI:: 10.3390/molecules25081825
PubMed:: 32316264

44.

Plantago asiatica Seed Extracts Alleviated Blood Pressure in Phase I⁻Spontaneous Hypertension Rats.

Cardiology

Fu YS et al (2019).; Molecules.
DOI:: 10.3390/molecules24091734
PubMed:: 31060204

45.

Plantago asiatica L. Ameliorates Puromycin Aminonucleoside-Induced Nephrotic Syndrome by Suppressing Inflammation and Apoptosis.

Immunology

Kho MC et al (2017).; Nutrients.
DOI:: 10.3390/nu9040386
PubMed:: 28420111

46.

Polysaccharide from seeds of Plantago asiatica L. affects lipid metabolism and colon microbiota of mouse.

Gastroenterology

Hu JL et al (2014).; J Agric Food Chem.
DOI:: 10.1021/jf4040942
PubMed:: 24341731