Plumbago scandens

Common Names: doctorbush, plumbago

Ethnobotanical Studies

Clinical Trials

[First observations on the topical use of Primin, Plumbagin and Maytenin in patients with skin cancer].

Melo AM et al (1974).
Rev Inst Antibiot (Recife).
PubMed:
4620478

Studies

TLC and HPLC methods for the determination of plumbagin for the diagnosis of poisoning by Plumbago scandens L.

Teixeira CJR et al (2024).
Toxicon.
DOI:
10.1016/j.toxicon.2024.107634
PubMed:
38307130

Chemical composition fluctuations in roots of Plumbago scandens L. in relation to floral development.

Paiva SR et al (2011).
An Acad Bras Cienc.
PubMed:
22146952

UV/Vis spectra and solubility of some naphthoquinones, and the extraction behavior of plumbagin from Plumbago scandens roots in supercritical CO2.

Rodrigues SV, Viana LM and Baumann W (2006).
Anal Bioanal Chem.
PubMed:
16791570

Antiparkinsonian-like effects of Plumbago scandens on tremorine-induced tremors methodology.

Summary

The effects of Plumbago scandens extracts were investigated on tremors in mice induced by tremorine, a model of Parkinson's disease. At low doses, the extracts did not have an effect, but at high doses of 1000-2000 mg/kg, they were effective in reducing tremors for up to an hour. Biperiden, an anticholinergic drug, was used as a control and also was effective. This suggests that Plumbago scandens may have potential therapeutic use in treating Parkinson's disease.

Neuroscience
Morais LC et al (2004).
Pharmacol Biochem Behav.
PubMed:
15582683

Plumbagin quantification in roots of Plumbago scandens L. obtained by different extraction techniques.

de Paiva SR et al (2004).
An Acad Bras Cienc.
PubMed:
15334248

Antimicrobial activity in vitro of plumbagin isolated from Plumbago species.

Antimicrobial
de Paiva SR et al (2003).
Mem Inst Oswaldo Cruz.
PubMed:
14762525

Intoxication of goats by Plumbago scandens in Northeastern Brazil.

Medeiros RM et al (2001).
Vet Hum Toxicol.
PubMed:
11383661

[Antimicrobial substances of superior plants. XXVII. Isolation of plumbagin from Plumbago scandens L].

Antimicrobial
de Lima OG et al (1968).
Rev Inst Antibiot (Recife).
PubMed:
5761015