Podophyllum hexandrum

Common Names: Himalayan mayapple

Ethnobotanical Studies

Studies

Foraging for the future: traditional culinary uses of wild plants in the Western Himalayas-Kashmir Valley (India).

Hassan M et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-024-00707-7
PubMed:
39003490

Dormancy release of seeds of Podophyllum hexandrum Royle accompanied by changes in phytochemicals and inorganic elements.

Jiu X et al (2023).
PLoS One.
DOI:
10.1371/journal.pone.0294673
PubMed:
37972141

Ethnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality control, conservation status and future prospective.

Summary

This review provides updated information on thirteen medicinal plants prioritized by the Indian government. It covers traditional uses, phytochemistry, pharmacology, quality control, and conservation status. Useful for understanding their importance and developing conservation strategies.

Review Phytochemistry
Anmol et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117385
PubMed:
37951375

Anthriscus sylvestris Deoxypodophyllotoxin Synthase Involved in Podophyllotoxin Biosynthesis.

Kobayashi K et al (2023).
Plant Cell Physiol.
DOI:
10.1093/pcp/pcad103
PubMed:
37948767

Cryopreservation of zygotic embryos of Podophyllum hexandrum Royle, an endangered medicinal plant, by vitrification and v cryo-plate techniques.

Parasher K et al (2023).
Cryo Letters.
PubMed:
37883139

PEGylated Graphene Oxide as a Nanodrug Delivery Vehicle for Podophyllotoxin (GO/PEG/PTOX) and In Vitro α-Amylase/α-Glucosidase Inhibition Activities.

Islam F et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c00888
PubMed:
37323383

Picropodophyllotoxin Inhibits Cell Growth and Induces Apoptosis in Gefitinib-Resistant Non-Small Lung Cancer Cells by Dual-Targeting EGFR and MET.

Cancer
Lee JY et al (2023).
Biomol Ther (Seoul).
DOI:
10.4062/biomolther.2022.113
PubMed:
36281696

Podophyllin in Dermatology: Revisiting a Historical Drug.

Singh A, Choudhary R and Ganguly S (2022).
Indian Dermatol Online J.
DOI:
10.4103/idoj.idoj_225_21
PubMed:
35198500

Structure-Based In Silico Investigation of Agonists for Proteins Involved in Breast Cancer.

Cancer
Roy A et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/7278731
PubMed:
35035508

Podophyllum hexandrum and its active constituents: Novel radioprotectants.

Review
Anand U et al (2022).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2021.112555
PubMed:
34954639

Picropodophyllotoxin Induces G1 Cell Cycle Arrest and Apoptosis in Human Colorectal Cancer Cells via ROS Generation and Activation of p38 MAPK Signaling Pathway.

Cancer
Lee SO et al (2021).
J Microbiol Biotechnol.
DOI:
10.4014/jmb.2109.09012
PubMed:
34528917

Insecticidal activity of twin compounds from podophyllotoxin and cytisine.

Zhang Y, Lv M and Xu H (2021).
Bioorg Med Chem Lett.
DOI:
10.1016/j.bmcl.2021.128104
PubMed:
33984477

Dirigent Proteins Guide Asymmetric Heterocoupling for the Synthesis of Complex Natural Product Analogues.

Kim SS and Sattely ES (2021).
J Am Chem Soc.
DOI:
10.1021/jacs.0c13164
PubMed:
33780244

Medicinal importance of Papra (Podophyllum hexandrum Royle) in Unani System of Medicine.

Review
Kalam MA et al (2021).
J Complement Integr Med.
DOI:
10.1515/jcim-2020-0178
PubMed:
33544520

Podophyllum hexandrum ameliorates endosulfan-induced genotoxicity and mutagenicity in freshwater cyprinid fish crucian carp.

Genetics
Dar SA et al (2017).
Pharm Biol.
PubMed:
27718769

Chilling temperature stimulates growth, gene over-expression and podophyllotoxin biosynthesis in Podophyllum hexandrum Royle.

Yang L, Sun P and Li MF (2016).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2016.06.010
PubMed:
27314513

Biochemical composition and antioxidant capacity of extracts from Podophyllum hexandrum rhizome.

Li M et al (2012).
BMC Complement Altern Med.
DOI:
10.1186/1472-6882-12-263
PubMed:
23259745

Radioprotection by Podophyllum hexandrum in the liver of mice: A mechanistic approach.

Kumar R et al (2005).
Environ Toxicol Pharmacol.
DOI:
10.1016/j.etap.2005.03.008
PubMed:
21783608

Podophyllum hexandrum (Himalayan mayapple) extract provides radioprotection by modulating the expression of proteins associated with apoptosis.

Kumar R et al (2005).
Biotechnol Appl Biochem.
PubMed:
15762843