Polygala senega

Common Names: Seneca snakeroot

Ethnobotanical Studies

Studies

New biofunctional effects of oleanane-type triterpene saponins.

Summary

Various triterpene saponins have shown potential benefits in the gastrointestinal tract, affecting alcohol and glucose levels, gastric emptying, transit, and mucosal lesions, with shared modes of action.

Review Phytochemistry
Matsuda H et al (2023).
J Nat Med.
DOI:
10.1007/s11418-023-01730-w
PubMed:
37436646

Medicinal Herbs in the Relief of Neurological, Cardiovascular, and Respiratory Symptoms after COVID-19 Infection A Literature Review.

Summary

COVID-19 can cause neurological complications, including anxiety, depression, MAD, and irreversible dementia, which can harm respiratory, circulatory, and heart function. Clinical trials suggest that phytotherapy, using natural plant materials like valeranon and apigenin, can aid these conditions. The study presents plant materials and their active compounds that can reduce post-COVID-19 complications, particularly those impacting the nervous system.

Review COVID-19Cardiology
Nawrot J et al (2022).
Cells.
DOI:
10.3390/cells11121897
PubMed:
35741026

Preparation of Tenuifolin from Polygala senega L. Root Using a Hydrolytic Continuous Flow System under High-Temperature, High-Pressure Conditions.

Shirahata T et al (2021).
J Org Chem.
DOI:
10.1021/acs.joc.1c01125
PubMed:
34730980

Anticancer potentials of root extract of Polygala senega against benzo[a]pyrene-induced lung cancer in mice.

Cancer
Paul S et al (2011).
Zhong Xi Yi Jie He Xue Bao.
PubMed:
21419086

Anticancer Potentials of Root Extract of Polygala senega and Its PLGA Nanoparticles-Encapsulated Form.

Cancer
Paul S et al (2011).
Evid Based Complement Alternat Med.
DOI:
10.1155/2011/517204
PubMed:
20953431

Anti-inflammatory effect of Inonotus obliquus, Polygala senega L., and Viburnum trilobum in a cell screening assay.

Immunology
Van Q et al (2009).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2009.06.026
PubMed:
19577624

Adjuvant activities of saponins from the root of Polygala senega L.

Phytochemistry
Katselis GS et al (2007).
Can J Physiol Pharmacol.
PubMed:
18066120

Isolation and evaluation of immunological adjuvant activities of saponins from Polygala senega L.

Phytochemistry
Estrada A et al (2000).
Comp Immunol Microbiol Infect Dis.
PubMed:
10660256

A prosapogenin from Polygala senega and Polygala tenuifolia.

Pelletier SW and Nakamura S (1967).
Tetrahedron Lett.
PubMed:
6080933