Polygonatum cyrtonema

Ethnobotanical Studies

Studies

Incorporation of Polygonatum cyrtonema extracts of NADES into chitosan/soybean isolate protein films: Impact on sweet cherry storage quality.

Pan J et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.141048
PubMed:
39241424

Traditional Processing Can Enhance the Medicinal Effects of Polygonatum cyrtonema by Inducing Significant Chemical Changes in the Functional Components in Its Rhizomes.

Shen J et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17081074
PubMed:
39204179

Effects of Fertilizer Application Intensity on Carbon Accumulation and Greenhouse Gas Emissions in Moso Bamboo Forest-Polygonatum cyrtonema Hua Agroforestry Systems.

Chen H et al (2024).
Plants (Basel).
DOI:
10.3390/plants13141941
PubMed:
39065468

Investigation of the Functional Components in Health Beverages Made from Polygonatum cyrtonema Rhizomes Provides Primary Evidence to Support Their Claimed Health Benefits.

Song Q et al (2024).
Metabolites.
DOI:
10.3390/metabo14070376
PubMed:
39057699

Polygonati Rhizoma varieties and origins traceability based on multivariate data fusion combined with an artificial intelligence classification algorithm.

Chen P et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.140350
PubMed:
39032291

Integrative analyses of metabolome and transcriptome reveal the dynamic accumulation and regulatory network in rhizomes and fruits of Polygonatum cyrtonema Hua.

Genetics
Ning L et al (2024).
BMC Genomics.
DOI:
10.1186/s12864-024-10608-4
PubMed:
39030489

Effect of ultrasonic degradation on the physicochemical characteristics, GLP-1 secretion, and antioxidant capacity of Polygonatum cyrtonema polysaccharide.

Summary

Ultrasonic degradation of Polygonatum cyrtonema polysaccharide alters physical and biological properties without changing structure, enhancing bioactivity for GLP-1 secretion, antioxidant, and enzyme inhibition. Controlled ultrasound can improve PCP as a functional agent.

ImmunologyPhytochemistry
Liu W et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.133434
PubMed:
38936570

Transcriptomic Analysis Reveals the Flavonoid Biosynthesis Pathway Involved in Rhizome Development in Polygonatum cyrtonema Hua.

Phytochemistry
Wan K et al (2024).
Plants (Basel).
DOI:
10.3390/plants13111524
PubMed:
38891332

Quality analysis and function prediction of soil microbial communities of Polygonatum cyrtonema in two indigenous-origins.

Yang L et al (2024).
Front Microbiol.
DOI:
10.3389/fmicb.2024.1410501
PubMed:
38881668

The structure change of polygonatum polysaccharide and the protect effect of Polygonatum crtonema Hua extracts and polysaccharide on cisplatin-induced AKI mice during nine-steam-nine-bask processing.

Yao X et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.132290
PubMed:
38795899

Quality Evaluation of Polygonatum cyrtonema Hua Based on UPLC-Q-Exactive Orbitrap MS and Electronic Sensory Techniques with Different Numbers of Steaming Cycles.

Wang M et al (2024).
Foods.
DOI:
10.3390/foods13101586
PubMed:
38790887

Differentiation of Polygonatum Cyrtonema Hua from Different Geographical Origins by near-Infrared Spectroscopy with Chemometrics.

Hao JW et al (2024).
J AOAC Int.
DOI:
10.1093/jaoacint/qsae036
PubMed:
38733574

Property and quality of japonica rice cake prepared with Polygonatum cyrtonema powder.

Zheng T et al (2024).
Food Chem X.
DOI:
10.1016/j.fochx.2024.101370
PubMed:
38623510

Identification Markers Responsible for Differentially Processed Polygonatum cyrtonema Hua by Ultra-Performance Liquid Chromatography with Quadruple-Time-of-Flight Mass Spectrometry.

Phytochemistry
Nie R et al (2024).
Molecules.
DOI:
10.3390/molecules29071559
PubMed:
38611838

Metabolomics and HS-SPME-GC-MS-based analysis of quality succession patterns and flavor characteristics changes during the fermentation of Lycium barbarum and Polygonatum cyrtonema compound wine.

Zhang JG et al (2024).
Food Res Int.
DOI:
10.1016/j.foodres.2024.114270
PubMed:
38609246

The accumulation of active ingredients of Polygonatum cyrtonema Hua is associated with soil characteristics and bacterial community.

Zhang Q et al (2024).
Front Microbiol.
DOI:
10.3389/fmicb.2024.1347204
PubMed:
38559348

Anti-Aging in Caenorhabditis elegans of Polysaccharides from Polygonatum cyrtonema Hua.

Zhang X et al (2024).
Molecules.
DOI:
10.3390/molecules29061276
PubMed:
38542911

Comprehensive Evaluation of the Nutritional Properties of Different Germplasms of Polygonatum cyrtonema Hua.

Lu M et al (2024).
Foods.
DOI:
10.3390/foods13060815
PubMed:
38540805

Enhanced hypoglycemic effects of konjac glucomannan combined with Polygonatum cyrtonema Hua polysaccharide in complete nutritional liquid diet fed type 2 diabetes mice.

Summary

Study: KGM and PCP supplement combo in T2DM mice on liquid diet improves postprandial glucose, long-term glucose metabolism. Benefits include gut health, weight, and liver function.

Diabetes
Chang L et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.131121
PubMed:
38522692

Processed Polygonatum cyrtonema Hua attenuates postpartum depression in rat model by regulating monoamines and hormones.

Summary

Researchers studied the effects of Hua on postpartum depression in rats. Hua can regulate liver, Qi, heart, blood, lungs, kidneys, and treat emotional diseases. It could potentially be a natural remedy for postpartum depression.

Neuroscience
Zhu XH et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e26895
PubMed:
38449668

Synergistic effect of Panax ginseng, Polygonatum cyrtonema, Epiphyllum oxypetalum, Nelumbo nucifera and Osmanthus fragrans extracts on skin aging regulation. From in silico predictions to in vitro outcome.

Feng C et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e26131
PubMed:
38449662

Accumulation mechanism of metabolite markers identified by machine learning between Qingyuan and Xiushui counties in Polygonatum cyrtonema Hua.

Gong Q et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-04871-6
PubMed:
38443808

Modulatory effects of fermented Polygonatum cyrtonema Hua on immune homeostasis and gut integrity in a dextran-sulfate-sodium-induced colitis model.

Gastroenterology
Li T et al (2024).
Food Funct.
DOI:
10.1039/d3fo04556k
PubMed:
38440931

Network pharmacology analysis, molecular docking integrated experimental verification reveal β-sitosterol as the active anti-NSCLC ingredient of Polygonatum cyrtonema Hua by suppression of PI3K/Akt/HIF-1α signaling pathway.

Cao W et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117900
PubMed:
38432577

Cercospora polygonatum, a new species causing gray leaf spot disease in Polygonatum cyrtonema.

Yin F et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-02-24-0327-SR
PubMed:
38386296

Novel Pestalotiopsis that causes gray spot disease of Polygonatum cyrtonema Hua in Hunan Province of China.

Sun L et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-12-23-2743-SC
PubMed:
38381962

Distinct toxic effects, gene expression profiles, and phytohormone responses of Polygonatum cyrtonema exposed to two different antibiotics.

Genetics
Yang G et al (2024).
J Hazard Mater.
DOI:
10.1016/j.jhazmat.2024.133639
PubMed:
38309169

Effective separation of protein from Polygonatum cyrtonema crude polysaccharide utilizing ionic liquid tetrabutylammonium bromide.

Xu Y et al (2024).
Front Chem.
DOI:
10.3389/fchem.2023.1287571
PubMed:
38260046

Review of studies on polysaccharides, lignins and small molecular compounds from three Polygonatum Mill. (Asparagaceae) spp. in crude and processed states.

Review
Zhang Q, Yang Z and Su W (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.129511
PubMed:
38242391

Liposomes enhance the immunological activity of Polygonatum cyrtonema Hua polysaccharides.

Liu D et al (2024).
J Pharm Sci.
DOI:
10.1016/j.xphs.2024.01.005
PubMed:
38237668

Unlocking hormesis and toxic effects induced by cadmium in Polygonatum cyrtonema Hua based on morphology, physiology and metabolomics.

Yang L et al (2024).
J Hazard Mater.
DOI:
10.1016/j.jhazmat.2024.133447
PubMed:
38219579

Structural characteristics of steamed Polygonatum cyrtonema polysaccharide and its bioactivity on colitis via improving the intestinal barrier and modifying the gut microbiota.

Gastroenterology
Gong H et al (2024).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2023.121669
PubMed:
38171660

Safe utilization evaluation of two typical traditional Chinese medicinal materials in Cd-contaminated soil based on the analysis of Cd transfer and AHP model.

Yang L et al (2023).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2023.169741
PubMed:
38160833

Structural characterization and in vitro fermentation properties of polysaccharides from Polygonatum cyrtonema.

Cheng Y et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.128877
PubMed:
38134995

Unveiling the immunomodulatory mechanism of polysaccharides from Polygonum cyrtonema based on RNA-seq.

Summary

PCP-80% activates immune response in cells, leading to increased protein expression and release of molecules linked to inflammation. It also affects gene expression through various signaling pathways. This suggests that PCP-80% can effectively modulate immune response in macrophages.

GeneticsImmunology
Shan J et al (2024).
Food Res Int.
DOI:
10.1016/j.foodres.2023.113755
PubMed:
38129053

Transcriptome analysis of three medicinal plants of the genus Polygonatum: identification of genes involved in polysaccharide and steroidal saponins biosynthesis.

Summary

Study on the synthesis of active components in Polygonati Rhizoma found differentially expressed genes and transcription factors related to polysaccharides and saponins. Provides a transcriptome dataset and lays foundation for improving active component content using molecular methods.

GeneticsPhytochemistry
Lu J et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1293411
PubMed:
38046616

First report of leaf spot disease caused by Alternaria alternata on Polygonatum cyrtonema Hua in Hunan Province of China.

Fan QJ et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-09-23-1976-PDN
PubMed:
38037209

First Report of Apiospora arundinis Causing Leaf Spot on Polygonatum cyrtonema Hua in China.

Gong Z et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-08-23-1580-PDN
PubMed:
38035782

Effects of the Fibrous Root of Polygonatum cyrtonema Hua on Growth Performance, Meat Quality, Immunity, Antioxidant Capacity, and Intestinal Morphology of White-Feathered Broilers.

GastroenterologyImmunology
Zhang T et al (2023).
Antibiotics (Basel).
DOI:
10.3390/antibiotics12111627
PubMed:
37998829

Branched fructo-oligosaccharides from Polygonatum Cyrtonema Hua as crosslinking agents for cellulose: A novel injectable and on-demand dissolution hydrogel for diabetic wound.

Summary

The researchers developed an injectable hydrogel using fructo-oligosaccharides derived from Polygonatum Cyrtonema Hua. It showed improved wound healing in diabetic mice and has potential for clinical use.

Diabetes
Ma H et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.128028
PubMed:
37952806

Effects of topping on rhizome, and analysis of chemical composition, antioxidant activity and α-amylase and α-glucosidase inhibition of the aerial parts in Polygonatum cyrtonema.

Summary

Topping the aerial part of Polygonatum cyrtonema increases rhizome yield and saponin content. The stem, leaves, and flowers have strong antioxidant and hypoglycemic activities, along with high polyphenol, flavonoid, protein, and amino acid content. This research suggests the potential for developing these parts for various applications.

Immunology
Tang W, Chen Y and Guo F (2023).
PLoS One.
DOI:
10.1371/journal.pone.0287894
PubMed:
37917721

First Report of Polygonatum cyrtonema Hua Root Rot Caused by Trichoderma virens in China.

Gong Z et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-08-23-1647-PDN
PubMed:
37877993

Plant fructans: Recent advances in metabolism, evolution aspects and applications for human health.

Review
Shi Y et al (2023).
Curr Res Food Sci.
DOI:
10.1016/j.crfs.2023.100595
PubMed:
37744554

Structural characterization and antioxidant activity of processed polysaccharides PCP-F1 from Polygonatum cyrtonema Hua.

Summary

This study explores the potential therapeutic properties of crude polysaccharides extracted from Hua (PCPs). Understanding their benefits could inform future medical and culinary applications of this traditional Chinese herb, providing opportunities for research and development in healthcare and nutrition.

Immunology
Zhao Y et al (2023).
Front Nutr.
DOI:
10.3389/fnut.2023.1272977
PubMed:
37731400

Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation.

Summary

P. cyrtonema Hua is used in traditional Chinese medicine to treat depression syndrome. The study examines the effects of its active component, PSP, on PTSD and its mechanisms. Results are unknown.

ImmunologyNeuroscience
Xie P et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117165
PubMed:
37696440

Genetic diversity and population structure of Polygonatum cyrtonema Hua in China using SSR markers.

Liu H et al (2023).
PLoS One.
DOI:
10.1371/journal.pone.0290605
PubMed:
37651363

Comparative Transcriptome Profiling Reveals Two WRKY Transcription Factors Positively Regulating Polysaccharide Biosynthesis in Polygonatum cyrtonema.

Genetics
Jiang W et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms241612943
PubMed:
37629123

First Report of Anthracnose Caused by Colletotrichum spaethianum on Iris lactea in Daqing, China.

Lihua Y et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-06-23-1040-PDN
PubMed:
37528339

Effects of Solid Fermentation on Polygonatum cyrtonema Polysaccharides: Isolation, Characterization and Bioactivities.

Cheng Y et al (2023).
Molecules.
DOI:
10.3390/molecules28145498
PubMed:
37513370

Exploring the effects of the fermentation method on the quality of Lycium barbarum and Polygonatum cyrtonema compound wine based on LC-MS metabolomics.

Wang JJ et al (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2023.136770
PubMed:
37421664

Proteomic analysis reveals that Polygonatum cyrtonema Hua polysaccharide ameliorates mice muscle atrophy in chemotherapy-induced cachexia.

Summary

In this study, researchers investigated the effects of Polygonatum cyrtonema Hua polysaccharide (PCP) on muscle atrophy caused by chemotherapy. They found that PCP, a compound derived from Polygonati Rhizoma herb, significantly reduced muscle loss and muscle fiber atrophy in mice. It also suppressed the decrease in immunoglobulin levels and the increase in pro-inflammatory factor interleukin-6 (IL-6). Proteomic analysis identified two primary targets of PCP: diacylglycerol kinase (DGKζ) and cathepsin L (CTSL). The study suggests that PCP regulates the autophagy-lysosome and ubiquitin-proteasome systems, providing a potential treatment for chemotherapy-induced muscle atrophy.

Cancer
Tang XY et al (2023).
J Pharm Biomed Anal.
DOI:
10.1016/j.jpba.2023.115533
PubMed:
37336040

Comprehensive Quality Evaluation of Polygonatum cyrtonema and Its Processed Product: Chemical Fingerprinting, Determination and Bioactivity.

Zhang J et al (2023).
Molecules.
DOI:
10.3390/molecules28114341
PubMed:
37298820

Metabolic Composition and Quality Traits of Polygonatum cyrtonema Hua from Different Germplasms and Age Sections Based on Widely Targeted Metabolomics Analysis.

Wang Q et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24076077
PubMed:
37047050

Polygonatum cyrtonema Hua Polysaccharide Alleviates Fatigue by Modulating Osteocalcin-Mediated Crosstalk between Bones and Muscles.

Li XY et al (2023).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.2c08192
PubMed:
37043685

[Inhibitory effect of three strains of biocontrol microbes on pathogens causing rhizome rot of Polygonatum cyrtonema].

Zheng MQ et al (2023).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20221203.102
PubMed:
37005805

Comparative proteome profiles of Polygonatum cyrtonema Hua rhizomes (Rhizoma Ploygonati) in response to different levels of cadmium stress.

Song R et al (2023).
BMC Plant Biol.
DOI:
10.1186/s12870-023-04162-6
PubMed:
36935490

Effects of different steaming times on the composition, structure and immune activity of Polygonatum Polysaccharide.

Su LL et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116351
PubMed:
36914038

Polygonati Rhizoma Polysaccharide Prolongs Lifespan and Healthspan in Caenorhabditis elegans.

Luan Y et al (2023).
Molecules.
DOI:
10.3390/molecules28052235
PubMed:
36903481

A Novel Method for the Pre-Column Derivatization of Saccharides from Polygonatum cyrtonema Hua. by Integrating Lambert-Beer Law and Response Surface Methodology.

Liu H et al (2023).
Molecules.
DOI:
10.3390/molecules28052186
PubMed:
36903433

Characterization of the chloroplast genome of medicinal herb Polygonatum cyrtonema and identification of molecular markers by comparative analysis.

Genetics
Xie ZN et al (2023).
Genome.
DOI:
10.1139/gen-2022-0087
PubMed:
36763968

Extraction and identification of steroidal saponins from Polygonatum cyrtonema Hua using natural deep eutectic solvent-synergistic quartz sand assisted extraction method.

Phytochemistry
Liu G et al (2023).
J Sep Sci.
DOI:
10.1002/jssc.202200823
PubMed:
36740903

Effect of fermentation methods on the quality and in vitro antioxidant properties of Lycium barbarum and Polygonatum cyrtonema compound wine.

Wang JJ et al (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2022.135277
PubMed:
36586271

Revealing the mechanisms of the bioactive ingredients accumulation in Polygonatum cyrtonema by multiomics analyses.

Xue T et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.1055721
PubMed:
36466239

Effects of Polygonatum cyrtonema extracts on the antioxidant ability, physical and structure properties of carboxymethyl cellulose-xanthan gum-flaxseed gum active packaging films.

Zheng M et al (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2022.134320
PubMed:
36162267

Effects of steam on polysaccharides from Polygonatum cyrtonema based on saccharide mapping analysis and pharmacological activity assays.

Chen Z et al (2022).
Chin Med.
DOI:
10.1186/s13020-022-00650-3
PubMed:
35978410

Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis.

Pain
Shen F et al (2022).
Oxid Med Cell Longev.
DOI:
10.1155/2022/2566917
PubMed:
35498131

Structures of fructan and galactan from Polygonatum cyrtonema and their utilization by probiotic bacteria.

Zhang J et al (2021).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2021.118219
PubMed:
34119173

Polygonatum cyrtonema Hua polysaccharide exhibits anti-fatigue activity via regulating osteocalcin signaling.

Shen WD et al (2021).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2021.01.200
PubMed:
33548311

Transcriptome analysis of Polygonatum cyrtonema Hua: identification of genes involved in polysaccharide biosynthesis.

Genetics
Wang C et al (2019).
Plant Methods.
DOI:
10.1186/s13007-019-0441-9
PubMed:
31289459

Polygonatum cyrtonema lectin, a potential antineoplastic drug targeting programmed cell death pathways.

Review
Wang SY et al (2011).
Biochem Biophys Res Commun.
DOI:
10.1016/j.bbrc.2011.02.049
PubMed:
21329660