Common Names: creeping cinquefoil
Potentilla reptans root extract shows potential for protecting the brain and reducing beta-amyloid in a rat model, indicating possible benefits for stroke and neurodegenerative diseases.
PEF from P. reptans root improved cell viability and reduced apoptosis in H9C2 myoblasts under I/R conditions by regulating lncRNAs H19 and MIAT. Cardioprotective potential.
A study found that COVID-19 can cause heart problems through its effect on ACE2. Researchers discovered that compounds found in L. root may protect the heart by inhibiting ACE and other proteins involved in cardiac function. These compounds showed potential as natural anti-SARS-CoV-2 agents in molecular docking studies. Triterpenoids found in L. root were particularly effective in inhibiting ACE and had good drug-like properties. The study suggests that L. root may have a protective effect on the heart during COVID-19 infection.