Common Names: common selfheal
Selenium nanoparticles stabilized by heteroxylan polysaccharide have potential as an anti-tumor agent for pancreatic cancer, showing inhibition of cell proliferation, migration, and induction of apoptosis and autophagy.
Researchers developed a modified anti-cancer drug, ZSP-M, based on Zeng-Sheng-Ping, with high efficacy and low toxicity for oral cancer. They aim to understand its pharmacodynamic material basis and its effect on tumor-associated macrophages. This could lead to potentially effective treatments for oral squamous cell carcinoma.
"SKI306X, made from three oriental herbs, reduces neuropathic pain in mice with chronic postischemic pain and spinal nerve ligation. It shows dose-dependent antiallodynic effects by decreasing GFAP levels."
Researchers studied the way () fights digestive tumors and decreases toxicity. This information may help develop better treatments for these types of cancer.
P vulgaris may help treat mastitis, but evidence is lacking. Further research needed to validate its effectiveness and understand how it works.
PV-1, a herbal mixture, showed immune-stimulatory and anti-inflammatory effects. It inhibited lung and oral cancer development in mouse models, increased CD8+ TILs, suppressed g-MDSCs, and improved anti-cancer immunotherapy. PV-1 has potential for cancer chemoprevention and immune remodeling.
Prunella vulgaris, a herb in traditional Chinese medicine, was tested on myocardial infarction (MI) rat models. It improved cardiac function, protected against apoptosis, and suppressed inflammation and fibrosis through inhibiting NLRP3 activation. The active components were caffeic acid, ursolic acid, and rosmarinic acid.
Researchers used network pharmacology and molecular docking techniques to study the therapeutic effects of Prunella vulgaris on thyroid cancer. The findings could provide potential drug targets for treating thyroid cancer.
Total phenolic and flavonoid concentrations of Prunella vulgaris varied across geographical regions. Antioxidant and anti-α-glucosidase activities were found to be superior in flavonoids. Analysis identified 32 compounds, confirming potential use of P. vulgaris as functional tea.
Xiao-Ai Jie-Du decoction is a treatment for DLBCL with varying prescriptions. It has shown effectiveness in clinical practice.
This study analyzed the chemical compounds in different parts of Prunella vulgaris and found 117 compounds, including phenolic acids, flavonoids, and triterpenoid saponins. The stem and leaf showed potential application value and the seed contained salviaflaside, a marker compound for quality evaluation of Prunellae Spica.
Scientists studied the herb Prunella vulgaris L. (PVL) and its potential benefits for the liver. PVL has been traditionally used to protect liver function and has shown potential in treating liver diseases. However, the specific mechanisms by which it benefits mice with alcoholic liver disease (ALD) are still unknown.
The study reports the first complete mitochondrial genome of (Lamiaceae), revealing gene content, codon preference, intercellular gene transfer, phylogeny, and RNA editing. The findings contribute to understanding the biology of and can inform future research studies.
L, a Chinese herb, may help treat COVID-19-associated acute kidney injury. Key target genes inhibited by its compounds were identified, suggesting potential therapeutic benefits that require further study.
Prunella vulgaris shows potential in treating papillary thyroid carcinoma by reducing activity and protein levels of key targets, through the core component kaempferol. A theoretical basis is provided for future research on effective components.