Common Names: bracken, bracken fern, brackenfern, northern bracken fern, western brackenfern
Three new flavonoid glycosides were isolated from the aerial of a plant. They may serve as chemotaxonomic markers for the species. These compounds also showed potential anti-inflammatory activity, inhibiting NF-κB induction by 46.3%, 59.6%, and 29.2%.
Scientists studied urothelial carcinoma (UC) in dogs, cats, and cattle exposed to a carcinogen. UC in these animals share similarities with aggressive bladder cancer in humans. Understanding these models can help develop strategies to identify key factors driving the disease in humans.
Researchers tested a collection of natural product extracts from popular botanical dietary supplements for their efficacy against SARS-CoV-2, the virus causing COVID-19. Out of 1867 extracts and 18 compounds, 310 extracts from 188 species were identified as having ≥ 50% viral entry inhibition activity at 20 µg/mL, with three extracts showing potent antiviral activity against both pseudotyped variants and infectious SARS-CoV-2. Two of these extracts were from Solidago altissima L. (Asteraceae) flowers and Pteridium aquilinum (L.) Kuhn (Dennstaedtiaceae) rhizomes. These findings could have important implications for the development of treatments for COVID-19 using botanical dietary supplements.