Pteris semipinnata

Ethnobotanical Studies

Studies

Natural diterpenoid EKO activates deubiqutinase ATXN3 to preserve vascular endothelial integrity and alleviate diabetic retinopathy through c-fos/focal adhesion axis.

Summary

EKO, a compound in Pteris semipinnata L., protects against vascular endothelial injury in diabetic retinopathy. It improves focal adhesion pathway and mitochondrial function, promising therapeutic potential.

Diabetes
Ge D et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.129341
PubMed:
38218272

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic acid loaded onto fluorescent mesoporous silica nanoparticles for the location and therapy of nasopharyngeal carcinoma.

Liu Y et al (2021).
Analyst.
DOI:
10.1039/d0an02388d
PubMed:
33475624

The High Content of Ent-11α-hydroxy-15-oxo-kaur- 16-en-19-oic Acid in Adenostemma lavenia (L.) O. Kuntze Leaf Extract: With Preliminary in Vivo Assays.

Hamamoto A et al (2020).
Foods.
DOI:
10.3390/foods9010073
PubMed:
31936516

Inhibition of breast cancer cell growth by the Pteris semipinnata extract ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid.

Cancer
Wu J et al (2017).
Oncol Lett.
DOI:
10.3892/ol.2017.7113
PubMed:
29344122

Pteisolic acid G, a novel ent-kaurane diterpenoid, inhibits viability and induces apoptosis in human colorectal carcinoma cells.

Qiu S et al (2017).
Oncol Lett.
DOI:
10.3892/ol.2017.6889
PubMed:
29113182

Synergistic anti-proliferative and pro-apoptotic activities of 5F and cisplatin in human non-small cell lung cancer NCI-H23 cells.

Cancer
Li Y et al (2017).
Oncol Lett.
DOI:
10.3892/ol.2017.6848
PubMed:
29098029

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis and cell cycle arrest in CNE-2Z nasopharyngeal carcinoma cells.

Wu K et al (2013).
Oncol Rep.
DOI:
10.3892/or.2013.2375
PubMed:
23563985

Ent-11α-Hydroxy-15-oxo-kaur-16-en-19-oic-acid Inhibits Growth of Human Lung Cancer A549 Cells by Arresting Cell Cycle and Triggering Apoptosis.

Cancer
Li L et al (2012).
Chin J Cancer Res.
DOI:
10.1007/s11670-012-0109-8
PubMed:
23358391

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis of human malignant cancer cells.

Review Cancer
Li MY, Liang NC and Chen GG (2012).
Curr Drug Targets.
PubMed:
23140284

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα.

Chen GG et al (2012).
Invest New Drugs.
DOI:
10.1007/s10637-011-9791-5
PubMed:
22227815

Pterisolic acids A-F, new ent-kaurane diterpenoids from the fern Pteris semipinnata.

Wang F et al (2011).
Chem Pharm Bull (Tokyo).
PubMed:
21467679

[Effect of 5F from Pteris semipinnata on expression of Nr1d1 in HO-8910PM cell line].

He T et al (2009).
Zhongguo Zhong Yao Za Zhi.
PubMed:
19673393

Uptake and accumulation of arsenic by 11 Pteris taxa from southern China.

Wang HB et al (2007).
Environ Pollut.
PubMed:
16777301

[Investigation on the chromatogram of diterpenoids in Pteris semipinnata by HPLC-APCI-MS].

Deng Y and Liang N (2005).
Zhong Yao Cai.
PubMed:
16104500

Over-expression of Bcl-2 against Pteris semipinnata L-induced apoptosis of human colon cancer cells via a NF-kappa B-related pathway.

Cancer
Chen GG et al (2004).
Apoptosis.
PubMed:
15314290

[Analysis of the diterpenoids in the extract of Pteris semipinnata L by HPLC-APCI-MS].

Deng YF, Liang NC and Liang T (2002).
Yao Xue Xue Bao.
PubMed:
12579802

Effects of antitumor compounds isolated from Pteris semipinnata L on DNA topoisomerases and cell cycle of HL-60 cells.

CancerGenetics
Li JH et al (1999).
Zhongguo Yao Li Xue Bao.
PubMed:
10678150