Reynoutria multiflora

Ethnobotanical Studies

Gelao ethnic minority, North Guizhou, China

Uses: Calming the mind/blackening the beard and hair

DOI:: 10.3389/fphar.2023.1217599
PubMed:: 37719846

Yi people, Mile, Yunnan, China

Uses: Constipation, lumbosacral pain, metrorrhagia

DOI:: 10.1186/s13002-024-00656-1
PubMed:: 38395900

Studies

Reynoutria multiflora (Thunb.) Moldenke and its ingredient suppress lethal prostate cancer growth by inducing CDC25B-CDK1 mediated cell cycle arrest.

Summary

PM, a traditional Chinese medicine, shows potential as a treatment for prostate cancer by suppressing cancer growth in an AR-dependent manner. This study investigates its anti-tumor mechanism in advanced prostate cancer.

Cancer

Zhou Q et al (2024).; Bioorg Chem.
DOI:: 10.1016/j.bioorg.2024.107731
PubMed:: 39180863

Processing of Reynoutria multiflora: transformation of catechin and gallic acid derivatives and their identification.

Bai J et al (2024).; Front Pharmacol.
DOI:: 10.3389/fphar.2024.1356876
PubMed:: 38469408

Alleviation of Glucocorticoid-Induced Osteoporosis in Rats by Ethanolic Reynoutria multiflora (Thunb.) Moldenke Extract.

Arthritis

Liu Y et al (2024).; J Med Food.
DOI:: 10.1089/jmf.2023.K.0105
PubMed:: 38442325

Jinfeng pills ameliorate premature ovarian insufficiency induced by cyclophosphamide in rats and correlate to modulating IL-17A/IL-6 axis and MEK/ERK signals.

Endocrinology Immunology

Hu YY et al (2023).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2023.116242
PubMed:: 36775079

Identification and localization of morphological feature-specific metabolites in Reynoutria multiflora roots.

Cai MT et al (2023).; Phytochemistry.
DOI:: 10.1016/j.phytochem.2022.113527
PubMed:: 36460140

Integrated spatially resolved metabolomics and network toxicology to investigate the hepatotoxicity mechanisms of component D of Polygonum multiflorum Thunb.

Jiang HY et al (2022).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2022.115630
PubMed:: 35987407

Transformation of Stilbene Glucosides From Reynoutria multiflora During Processing.

Bai J et al (2022).; Front Pharmacol.
DOI:: 10.3389/fphar.2022.757490
PubMed:: 35548344

Beware of the Potential Risks for Polygoni Multiflori Caulis-Induced Liver Injury.

Kong WS et al (2022).; Front Pharmacol.
DOI:: 10.3389/fphar.2022.868327
PubMed:: 35431961

Herb-Induced Liver Injury Related to Reynoutria multiflora (Thunb.) Moldenke: Risk Factors, Molecular and Mechanistic Specifics.

Review

Zhai XR et al (2021).; Front Pharmacol.
DOI:: 10.3389/fphar.2021.738577
PubMed:: 34539416

10.

Screening of Quality Markers During the Processing of Reynoutria multiflora Based on the UHPLC-Q-Exactive Plus Orbitrap MS/MS Metabolomic Method.

Bai J et al (2021).; Front Pharmacol.
DOI:: 10.3389/fphar.2021.695560
PubMed:: 34456722

11.

Lipidomics Analysis Indicates Disturbed Hepatocellular Lipid Metabolism in Reynoutria multiflora-Induced Idiosyncratic Liver Injury.

Wu X et al (2020).; Front Pharmacol.
DOI:: 10.3389/fphar.2020.569144
PubMed:: 33408629

12.

Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.

Yang N et al (2019).; Front Pharmacol.
DOI:: 10.3389/fphar.2019.00709
PubMed:: 31297058

13.

Susceptibility-Related Factor and Biomarkers of Dietary Supplement Polygonum multiflorum-Induced Liver Injury in Rats.

Tu C et al (2019).; Front Pharmacol.
DOI:: 10.3389/fphar.2019.00335
PubMed:: 31024306