Rotheca myricoides

Ethnobotanical Studies

Studies

In vitro study on efficacy of PHELA, an African traditional drug against SARS-CoV-2.

Summary

Researchers investigated an herbal combination of four African medicinal plants known as PHELA as a potential therapy for COVID-19. In vitro testing found that PHELA inhibited > 90% of SARS-CoV-2 and SARS-CoV infection as well as close to 100% of MERS-CoV infection. In silico docking studies showed strong binding energy interactions between compounds in PHELA and SARS-CoV-2 proteins. PHELA has potential as a COVID-19 therapeutic.

COVID-19
Matsabisa MG et al (2022).
Sci Rep.
DOI:
10.1038/s41598-022-13599-y
PubMed:
35718800

The complete chloroplast genome sequence of Rotheca myricoides (Hochst.) Steane & Mabb., a traditional medicinal plant.

Genetics
Fang X and Zhang S (2021).
Mitochondrial DNA B Resour.
DOI:
10.1080/23802359.2021.1966340
PubMed:
34435124

The freeze-dried extracts of Rotheca myricoides (Hochst.) Steane & Mabb possess hypoglycemic, hypolipidemic and hypoinsulinemic on type 2 diabetes rat model.

Diabetes
Chege BM et al (2019).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2019.112077
PubMed:
31369832

The development and use of a drug-induced immunosuppressed rat-model to screen Phela for mechanism of immune stimulation.

Lekhooa MR et al (2017).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2017.04.031
PubMed:
28473245

Correction to: 'The child that tiire doesn't give you, God won't give you either.' The role of Rotheca myricoides in Somali fertility practices.

(2018).
Anthropol Med.
DOI:
10.1080/13648470.2017.1301566
PubMed:
28267363

'The child that tiire doesn't give you, God won't give you either.' The role of Rotheca myricoides in Somali fertility practices.

Mire S et al (2016).
Anthropol Med.
PubMed:
27830941

Medicinal plants used for management of malaria among the Luhya community of Kakamega East sub-County, Kenya.

Mukungu N et al (2016).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2016.08.050
PubMed:
27586821

Mutagenic and antimutagenic properties of extracts from South African traditional medicinal plants.

Genetics
Verschaeve L and Van Staden J (2008).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2008.06.007
PubMed:
18602977