Rubia tinctorum

Common Names: dyer's madder, Indian madder, madder

Ethnobotanical Studies

Studies

Purpurin ameliorated neuropathic allodynia and hyperalgesia by modulating neuronal mitochondrial bioenergetics and redox status in type 1 diabetic mice.

Summary

Purpurin, a compound from Rubia tinctorum, relieves neuropathic pain in diabetic mice by enhancing bioenergetics and antioxidant effects. Could lead to improved therapy for diabetic patients with peripheral neuropathy.

DiabetesNeuroscience
Chen W et al (2024).
Eur J Pharmacol.
DOI:
10.1016/j.ejphar.2024.176749
PubMed:
38897444

Chromatic and medicinal properties of six natural textile dyes: A review of eucalyptus, weld, madder, annatto, indigo and woad.

Review
Santiago D, Cunha J and Cabral I (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e22013
PubMed:
38034740

Site-specific genotoxicity of rubiadin: localization and histopathological changes in the kidneys of rats.

Mitsumoto T et al (2023).
Arch Toxicol.
DOI:
10.1007/s00204-023-03610-4
PubMed:
37794257

Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview.

Review
Murthy HN et al (2022).
Metabolites.
DOI:
10.3390/metabo13010039
PubMed:
36676964

An eco-friendly method of extracting alizarin from Rubia tinctorum roots under supercritical carbon dioxide and its application to wool dyeing.

Abou Elmaaty T et al (2023).
Sci Rep.
DOI:
10.1038/s41598-022-27110-0
PubMed:
36593257

Multifunctional Nanocarriers Based on Chitosan Oligomers and Graphitic Carbon Nitride Assembly.

Santiago-Aliste A et al (2022).
Materials (Basel).
DOI:
10.3390/ma15248981
PubMed:
36556785

Study of Dyeing Process of Hemp/Cotton Fabrics by Using Natural Dyes Obtained from Rubia tinctorum L. and Calendula officialis.

Mijas G et al (2022).
Polymers (Basel).
DOI:
10.3390/polym14214508
PubMed:
36365502

SERS detection of anthraquinone dyes: Using solvothermal silver colloid as the substrate.

Zhu J et al (2022).
Spectrochim Acta A Mol Biomol Spectrosc.
DOI:
10.1016/j.saa.2022.121646
PubMed:
35926284

Noninvasive Characterization and Quantification of Anthraquinones in Dyed Woolen Threads by Visible Diffuse Reflectance Spectroscopy.

Chavanne C et al (2022).
Anal Chem.
DOI:
10.1021/acs.analchem.2c01073
PubMed:
35584233

Rubia tinctorum root extracts: chemical profile and management of type II diabetes mellitus.

Diabetes
Eltamany EE et al (2020).
RSC Adv.
DOI:
10.1039/d0ra03442h
PubMed:
35516188

Visualization of the distribution of anthraquinone components from madder roots in rat kidneys by desorption electrospray ionization-time-of-flight mass spectrometry imaging.

Ishii Y et al (2022).
Food Chem Toxicol.
DOI:
10.1016/j.fct.2022.112851
PubMed:
35139434

Consumption of nephrotoxic plants among chronic hemodialysis patients in the Eastern region of Morocco: A multicentric cross-sectional study.

Guitouni O et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.114972
PubMed:
34990766

Activity of Anthracenediones and Flavoring Phenols in Hydromethanolic Extracts of Rubia tinctorum against Grapevine Phytopathogenic Fungi.

Langa-Lomba N et al (2021).
Plants (Basel).
DOI:
10.3390/plants10081527
PubMed:
34451572

Development and validation of a liquid chromatographic method with diode array detection for the determination of anthraquinones, flavonoids and other natural dyes in aged silk.

Phytochemistry
Vasileiadou A, Karapanagiotis I and Zotou A (2021).
J Chromatogr A.
DOI:
10.1016/j.chroma.2021.462312
PubMed:
34171771

Alizarin and Purpurin from Rubia tinctorum L. Suppress Insulin Fibrillation and Reduce the Amyloid-Induced Cytotoxicity.

Wang W et al (2021).
ACS Chem Neurosci.
DOI:
10.1021/acschemneuro.1c00177
PubMed:
34033711

The History of Madder (Rubia Tinctorum).

Cameron GR et al (1932).
Ann Med Hist.
PubMed:
33944183

Antioxidant and Polyphenol-Rich Ethanolic Extract of Rubia tinctorum L. Prevents Urolithiasis in an Ethylene Glycol Experimental Model in Rats.

Phytochemistry
Marhoume FZ et al (2021).
Molecules.
DOI:
10.3390/molecules26041005
PubMed:
33672875

Composition of the metabolomic bio-coronas isolated from Ocimum sanctum and Rubia tinctorum.

Kurepa J and Smalle JA (2021).
BMC Res Notes.
DOI:
10.1186/s13104-020-05420-8
PubMed:
33407859

Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1).

Cancer
Lajkó E et al (2015).
Cancer Cell Int.
DOI:
10.1186/s12935-015-0271-4
PubMed:
26690297

Comparative studies of rubia cordifolia linn. And rubia tinctorum linn (rubiaceae)(*).

Dengre RG, Patel KN and Chauhan MB (1993).
Anc Sci Life.
PubMed:
22556644

The mutagenic constituents of Rubia tinctorum.

Genetics
Kawasaki Y, Goda Y and Yoshihira K (1992).
Chem Pharm Bull (Tokyo).
PubMed:
1394669