Rubus idaeus

Common Names: American red raspberry, common red raspberry, western red raspberry

Ethnobotanical Studies

Clinical Trials

Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial.

Scientists investigated the potential use of Rubus idaeus leaf extracts as a safe alternative treatment for osteoarthritis symptoms, aiming to reduce reliance on nonsteroidal anti-inflammatory drugs with severe side effects.

Henrotin Y et al (2022).
BMC Musculoskelet Disord.
PubMed:
35799169

Effect of Rubus idaeus L. Consumption During Pregnancy on Maternal Mice and Their Offspring.

This study looked at the effects of consuming red raspberry extract during pregnancy in mice. High doses led to shorter gestation, smaller litter size, and other changes in offspring.

Hastings-Tolsma M et al (2022).
J Med Food.
PubMed:
34714139

Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial.

Rattanawiwatpong P et al (2020).
J Cosmet Dermatol.
PubMed:
31975502

Studies

Altered expression of a raspberry homologue of VRN1 is associated with disruption of dormancy induction and misregulation of subsets of dormancy-associated genes.

Summary

Study on winter dormancy in red raspberry cultivars: 'Glen Ample' follows normal phenology, 'Glen Dee' shows dysregulation. RNA-seq and WGCNA identify gene clusters and highlight importance of genetic processes. Dysregulation in 'Glen Dee' linked to specific VRN1 homologue expression.

Mateos B et al (2024).
J Exp Bot.
PubMed:
39243357

The complete chloroplast genome sequence of red raspberry (Rubus idaeus L.) and phylogenetic analysis.

Summary

Researchers sequenced the complete chloroplast genome of red raspberries, revealing 127 genes and a close relationship to another raspberry species. This information improves our understanding of raspberry genetics and potential benefits for human health.

Zhou H and Zhang H (2024).
Mitochondrial DNA B Resour.
PubMed:
39234579

A new raspberry ketone synthesis gene RinPKS4 identified in Rubus idaeus L. by transcriptome analysis.

Summary

Scientists identified a gene (RinPKS4) responsible for raspberry ketone synthesis. Over-expression of this gene in raspberry increased ketone content by 42.64%. This study provides insight for future research on raspberry ketone production in red raspberries.

He Z et al (2024).
PLoS One.
PubMed:
39172993

Complementary approaches to dissect late leaf rust resistance in an interspecific raspberry population.

Prado M et al (2024).
G3 (Bethesda).
PubMed:
39172650

A comparison of raspberry freezing-damage during preservation in isochoric and isobaric conditions.

Câmpean ȘI et al (2024).
Front Nutr.
PubMed:
39135551

Reversed phase HPLC with UHPLC benefits for the determination of tocochromanols in the seeds of edible fruits in the Rosaceae family.

Górnaś P, Symoniuk E and Soliven A (2024).
Food Chem.
PubMed:
39126942

Expression of Concern: Starkute et al. Characteristics of Unripened Cow Milk Curd Cheese Enriched with Raspberry (Rubus idaeus), Blueberry (Vaccinium myrtillus) and Elderberry (Sambucus nigra) Industry By-Products. Foods 2023, 12, 2860.

Foods Editorial Office et al (2024).
Foods.
PubMed:
39063334

Screening Tests for the Interaction of Rubus idaeus and Rubus occidentalis Extracts with Antibiotics against Gram-Positive and Gram-Negative Human Pathogens.

Hałasa R et al (2024).
Antibiotics (Basel).
PubMed:
39061335

The species, density, and intra-plant distribution of mites on red raspberry (Rubus idaeus L.).

Tan JL et al (2024).
Exp Appl Acarol.
PubMed:
38937376

Underutilized Canadian wild berries as potential sources of lipophilic bioactive compounds with antihypertensive properties.

Kodikara C et al (2024).
Food Funct.
PubMed:
38920290

Transposable elements in Rosaceae: insights into genome evolution, expression dynamics, and syntenic gene regulation.

Yu Z et al (2024).
Hortic Res.
PubMed:
38919560

High-throughput color determination of red raspberry puree and correlation of color parameters with total anthocyanins.

Baldassi C et al (2024).
Plant Methods.
PubMed:
38812007

Effect of microbial biostimulants on the antioxidant profile, antioxidant capacity and activity of enzymes influencing the quality level of raspberries (Rubus idaeus L.).

Drobek M et al (2024).
Food Chem.
PubMed:
38795624

Chemical Profile and Bioactivity of Rubus idaeus L. Fruits Grown in Conventional and Aeroponic Systems.

La Torre C et al (2024).
Plants (Basel).
PubMed:
38674524

Raspberry leaf (Rubus idaeus) use in pregnancy: a prospective observational study.

Bowman RL, Taylor J and Davis DL (2024).
BMC Complement Med Ther.
PubMed:
38649906

Correlation between Antimicrobial Activity Values and Total Phenolic Content/Antioxidant Activity in Rubus idaeus L.

Summary

Researchers found that raspberry plant parts contain antibacterial compounds. Leaves, inflorescences, and fruits can combat Gram-positive bacteria. Root and seed extracts show lower activity. Using natural alternatives could replace synthetic antibiotics, offering economic and environmental benefits.

Ispiryan A et al (2024).
Plants (Basel).
PubMed:
38498473

Evaluation of Antioxidant, Anti-inflammatory, and Antimicrobial Activities of Raspberry Fruit Extract: An In Vitro Study.

Summary

Raspberry extract has strong antimicrobial, antioxidant, and anti-inflammatory properties, making it a promising natural remedy for oral health issues like mucosal lesions, cancer, and candidiasis. Additional studies are needed to confirm its potential benefits.

Gomathi R, Umamaheswari TN and Prethipa R (2024).
Cureus.
PubMed:
38481926

Bacteria Associated with Spores of Arbuscular Mycorrhizal Fungi Improve the Effectiveness of Fungal Inocula for Red Raspberry Biotization.

Ważny R et al (2024).
Microb Ecol.
PubMed:
38466433

The Effect of Rubus idaeus Polyphenols Extract in Induced Endometriosis in Rats.

Summary

Study found that RiDE may reduce endometriosis lesion size and modulate expression of MMP-2, MMP-9, and TGF-β1 in rats. RiDE plus dienogest reduced weight gain and lesion size more effectively than dienogest alone, potentially offering anti-inflammatory effects.

Jianu EM et al (2024).
Molecules.
PubMed:
38398530

Phytochemical profiling of red raspberry (Rubus idaeus L.) honey and investigation on compounds related to its pollen occurrence.

Leoni V et al (2024).
J Sci Food Agric.
PubMed:
38345434

Differences in primary metabolism related to quality of raspberry (Rubus idaeus L.) fruit under open field and protected soilless culture growing conditions.

Fuentealba C et al (2024).
Front Plant Sci.
PubMed:
38273957

Nutritionally Important Pro-Health Active Ingredients and Antioxidant Properties of Fruits and Fruit Juice of Selected Biennial Fruiting Rubus idaeus L. Cultivars.

Chwil M et al (2023).
Pharmaceuticals (Basel).
PubMed:
38139824

Quality Characteristics of Raspberry Fruits from Dormancy Plants and Their Feasibility as Food Ingredients.

Petronilho S, Coimbra MA and Passos CP (2023).
Foods.
PubMed:
38137248

Rubi idaei fructus as a Source of Bioactive Chemical Compounds with an Important Role in Human Health and Comparison of the Antioxidant Potential of Fruits and Juice of Three Repeat-Fruiting Rubus idaeus L. Cultivars.

Chwil M, Matraszek-Gawron R and Kostryco M (2023).
Metabolites.
PubMed:
37999220

Therapeutic Effects of Oral Application of Menthol and Extracts from Tormentil (Potentilla erecta), Raspberry Leaves (Rubus idaeus), and Loosestrife (Lythrum salicaria) during Acute Murine Campylobacteriosis.

Bandick R et al (2023).
Pharmaceutics.
PubMed:
37896170

Plant Extracts as Skin Care and Therapeutic Agents.

Review
Michalak M et al (2023).
Int J Mol Sci.
PubMed:
37895122

Chemical Characterization, Bioactivity and Toxicity of European Flora Plant Extracts in Search for Potential Natural Origin Preservatives.

Martins de Deus B et al (2023).
Plants (Basel).
PubMed:
37570937

Characteristics of Unripened Cow Milk Curd Cheese Enriched with Raspberry (Rubus idaeus), Blueberry (Vaccinium myrtillus) and Elderberry (Sambucus nigra) Industry By-Products.

Starkute V et al (2023).
Foods.
PubMed:
37569128

Fine-mesh exclusion netting reduces Drosophila suzukii (Diptera: Drosophilidae) infestation and improves organic fall-bearing raspberry yields.

Kuesel R et al (2023).
J Econ Entomol.
PubMed:
37548438

Physico-Chemical Properties, Fatty Acids Profile, and Economic Properties of Raspberry (Rubus idaeus L.) Seed Oil, Extracted in Various Ways.

Ispiryan A et al (2023).
Plants (Basel).
PubMed:
37514319

Raspberry Leaves and Extracts-Molecular Mechanism of Action and Its Effectiveness on Human Cervical Ripening and the Induction of Labor.

Review
Socha MW et al (2023).
Nutrients.
PubMed:
37513625

Comparison of red raspberry and wild strawberry fruits reveals mechanisms of fruit type specification.

Zhou J et al (2023).
Plant Physiol.
PubMed:
37440715

Reduction of methicillin-resistant Staphylococcus aureus biofilm growth and development using arctic berry extracts.

Aguilera-Correa JJ et al (2023).
Front Cell Infect Microbiol.
PubMed:
37424779

Arbuscular mycorrhizae influence raspberry growth and soil fertility under conventional and organic fertilization.

Lu Q et al (2023).
Front Microbiol.
PubMed:
37260690

Chromosome-scale genome sequence assemblies of the 'Autumn Bliss' and 'Malling Jewel' cultivars of the highly heterozygous red raspberry (Rubus idaeus L.) derived from long-read Oxford Nanopore sequence data.

Price RJ et al (2023).
PLoS One.
PubMed:
37192177

Abscisic Acid Synthesis and Signaling during the Ripening of Raspberry (Rubus idaeus 'Heritage') Fruit.

Álvarez F et al (2023).
Plants (Basel).
PubMed:
37176940

The importance of multi-year studies and commercial yield metrics in measuring pollinator dependence ratios: A case study in UK raspberries Rubus idaeus L.

Ryan IC, Dicks LV and Shutt JD (2023).
Ecol Evol.
PubMed:
37168988

First report of 'Candidatus Phytoplasma rubi' associated with Rubus stunt disease of raspberry and blackberry in the Czech Republic.

Franova J et al (2023).
Plant Dis.
PubMed:
37133341

Volatilomics of raspberry fruit germplasm by combining chromatographic and direct-injection mass spectrometric techniques.

Farneti B et al (2023).
Front Mol Biosci.
PubMed:
37122562

Molecular dynamics simulation of the interaction of a raspberry polygalacturonase (RiPG) with a PG inhibiting protein (RiPGIP) isolated from ripening raspberry (Rubus idaeus cv. Heritage) fruit as a model to understand proteins interaction during fruit softening.

Morales-Quintana L et al (2023).
J Mol Graph Model.
PubMed:
37116336

A Review on Berry Seeds-A Special Emphasis on Their Chemical Content and Health-Promoting Properties.

Review
Sławińska N, Prochoń K and Olas B (2023).
Nutrients.
PubMed:
36986152

Investigating Biochemical and Histopathological Responses between Raspberries and Aculeastrum americanum.

Dias MG et al (2023).
J Fungi (Basel).
PubMed:
36983505

Morphological Study of the Alimentary Canal and Malpighian Tubules in the Adult of the Pollen Beetle Meligethes (Odonthogethes) chinensis (Coleoptera: Nitidulidae: Meligethinae).

Chen L et al (2023).
Insects.
PubMed:
36975983

Reconnoitring the antioxidant and anti-bacterial potential of different fruits after tannin acyl hydrolase mediated biotransformation.

Rippin R, Sharma AK and Beniwal V (2023).
Biotechnol Appl Biochem.
PubMed:
36965069

LC-MS/MS method for quantification of raspberry ketone in rat plasma: application to preclinical pharmacokinetic studies.

Verma S et al (2023).
Bioanalysis.
PubMed:
36916612

First Report of Hemicycliophora Conida from Russia.

Tabolin S and Kolganova T (2022).
Helminthologia.
PubMed:
36694825

Influence of Seeds' Age and Clarification of Cold-Pressed Raspberry (Rubus idaeus L.) Oil on the DSC Oxidative Stability and Phase Transition Profiles.

Rajagukguk YV, Islam M and Tomaszewska-Gras J (2023).
Foods.
PubMed:
36673450

Rhododendrol, a reductive metabolite of raspberry ketone, suppresses the differentiation of 3T3‑L1 cells into adipocytes.

Uramaru N et al (2023).
Mol Med Rep.
PubMed:
36633126

The Modification of Substrate in the Soilless Cultivation of Raspberries (Rubus Idaeus L.) as a Factor Stimulating the Biosynthesis of Selected Bioactive Compounds in Fruits.

Balawejder M et al (2022).
Molecules.
PubMed:
36615315

UHPLC-Triple-TOF-MS Characterization, Antioxidant, Antimicrobial and Antiproliferative Activity of Raspberry (Rubus idaeus L.) Seed Extracts.

Marić B et al (2022).
Foods.
PubMed:
36613375

First report of Phytophthora gonapodyides causing root rot on raspberry in Canada.

Burlakoti RR et al (2023).
Plant Dis.
PubMed:
36607330

Long-term supplementation with anthocyanin-rich or -poor Rubus idaeus berries does not influence microvascular architecture nor cognitive outcome in the APP/PS-1 mouse model of Alzheimer's disease.

Summary

Researchers investigated whether feeding APP/PS-1 mice (a model for Alzheimer’s disease) raspberries could ameliorate microvascular pathology and improve cognition. Mice were fed glucose (control group), or glucose and red/yellow raspberries for 24 weeks and assessed post-intervention. However, long-term feeding of raspberries had limited effects on microvascular architecture or cognition, although there were changes in cerebral and plasmatic metabolites.

Alonso Torrens A et al (2022).
Int J Food Sci Nutr.
PubMed:
36450698

The In-Vitro Effect of Homeopathically Prepared Rubus idaeus and 680 nm Laser Irradiation on Cervical Cancer Cells.

Joubert KS et al (2023).
Homeopathy.
PubMed:
35835442

Red Raspberry (Rubus idaeus L.) Seed Oil: A Review.

Review
Ispiryan A, Viškelis J and Viškelis P (2021).
Plants (Basel).
PubMed:
34065144

Effect of Rubus idaeus Extracts in Murine Chondrocytes and Explants.

Bourmaud M et al (2021).
Biomolecules.
PubMed:
33572124

Phenolic Composition, Mineral Content, and Beneficial Bioactivities of Leaf Extracts from Black Currant (Ribes nigrum L.), Raspberry (Rubus idaeus), and Aronia (Aronia melanocarpa).

Staszowska-Karkut M and Materska M (2020).
Nutrients.
PubMed:
32059465

Raspberry.

Review
(2021).
PubMed:
30000844

Dietary Plants for the Prevention and Management of Kidney Stones: Preclinical and Clinical Evidence and Molecular Mechanisms.

Meta-Analysis
Nirumand MC et al (2018).
Int J Mol Sci.
PubMed:
29518971