Rumex aquaticus

Common Names: western dock

Ethnobotanical Studies

Boreal Forest, Canada

Uses: Circulatory system disorders, Dermatological infections, Injuries, Musculoskeletal disorders

DOI:: 10.1186/1746-4269-8-7
PubMed:: 22289509

Studies

Antibacterial screening of Rumex species native to the Carpathian Basin and bioactivity-guided isolation of compounds from Rumex aquaticus.

Orbán-Gyapai O et al (2017).; Fitoterapia.
DOI:: 10.1016/j.fitote.2017.03.009
PubMed:: 28300698

The protective mechanism of QGC in feline esophageal epithelial cells by interleukin-1β treatment.

Jang HS et al (2017).; Arch Pharm Res.
DOI:: 10.1007/s12272-016-0858-x
PubMed:: 28012047

The cytoprotective effect of Rumex Aquaticus Herba extract against hydrogen peroxide-induced oxidative stress in AGS cells.

Cho EJ et al (2016).; Arch Pharm Res.
DOI:: 10.1007/s12272-016-0863-0
PubMed:: 27885462

The protective mechanism of quercetin-3-O-β-D-glucuronopyranoside (QGC) in H2O2-induced injury of feline esophageal epithelial cells.

Sohn US et al (2016).; Arch Pharm Res.
DOI:: 10.1007/s12272-016-0808-7
PubMed:: 27522656

Effect of Rumex Aquaticus Herba Extract Against Helicobacter pylori-Induced Inflammation in Gastric Epithelial Cells.

Immunology

Han JH, Khin PP and Sohn UD (2016).; J Med Food.
DOI:: 10.1089/jmf.2015.3473
PubMed:: 26580421

Flavonoids isolated from Rumex aquaticus exhibit neuroprotective and neurorestorative properties by enhancing neurite outgrowth and synaptophysin.

Summary

Researchers have isolated two flavonoids from the Rumex aquaticus plant, quercetin-3-O-galactoside and quercetin-3-O-arabinoside, which show promise in protecting brain cells from damage caused by ischemic stroke. The study used a rat cell line and found that the flavonoids significantly improved cell survival and neurite outgrowth in a model of ischemia. Additionally, one of the flavonoids was found to enhance the expression of synaptophysin, a marker of synapses and synaptic plasticity. These results suggest that the flavonoids could be useful in promoting stroke recovery by protecting and promoting the growth of brain cells.

Neuroscience Phytochemistry

Orbán-Gyapai O et al (2014).; CNS Neurol Disord Drug Targets.
PubMed:: 25345505

Effect of ECQ on Iodoacetamide-Induced Chronic Gastritis in Rats.

Lee SE et al (2013).; Korean J Physiol Pharmacol.
DOI:: 10.4196/kjpp.2013.17.5.469
PubMed:: 24227950

Anti-Oxidative and Anti-Inflammatory Effects of QGC in Cultured Feline Esophageal Epithelial Cells.

Immunology

Lee MJ et al (2013).; Korean J Physiol Pharmacol.
DOI:: 10.4196/kjpp.2013.17.1.81
PubMed:: 23440684

Protective Effect of ECQ on Rat Reflux Esophagitis Model.

Jang HS et al (2012).; Korean J Physiol Pharmacol.
DOI:: 10.4196/kjpp.2012.16.6.455
PubMed:: 23269908

10.

Protective effect of extract from Rumex aquaticus herba on ethanol-induced gastric damage in rats.

Gastroenterology

Kwak HS et al (2012).; Pharmacology.
DOI:: 10.1159/000342767
PubMed:: 23037147

11.

Antiproliferative activity of polygonaceae species from the Carpathian Basin against human cancer cell lines.

Cancer

Lajter I et al (2013).; Phytother Res.
DOI:: 10.1002/ptr.4690
PubMed:: 22473656

12.

The Inhibitory Effect of Quercetin-3-O-beta-D-Glucuronopyranoside on Gastritis and Reflux Esophagitis in Rats.

Min YS et al (2009).; Korean J Physiol Pharmacol.
DOI:: 10.4196/kjpp.2009.13.4.295
PubMed:: 19885013