Common Names: curly dock, narrowleaf dock, sour dock, yellow dock
Water-soluble compounds from plants were tested for their anti-cancer properties against colorectal cancer cells. The most potent compound, L19, showed dose-dependent anti-proliferative activity and induced apoptosis through activation of caspases and inflammatory pathways. L19 can be a starting point for developing new cancer treatments.
Researchers evaluated three solvents of increasing polarity to extract phenolic compounds from the aerial part of L. plant. The methanol extract had significant anti-oxidant and anti-cholinesterase activities, while the dichloromethane extract had the highest cytotoxic activity against cancer cells. GC-MS analysis identified three new compounds, and HPLC chromatograms showed several phenolic compounds. The study suggests that L. plant extracts could be considered as natural supplements for food and pharmaceuticals due to their phenolic compounds.