Ruscus aculeatus

Ethnobotanical Studies

Clinical Trials

Efficacy and safety of a Butcher's broom preparation (Ruscus aculeatus L. extract) compared to placebo in patients suffering from chronic venous insufficiency.

Vanscheidt W et al (2002).
Arzneimittelforschung.
PubMed:
12040966

Studies

Design of an Herbal Preparation Composed by a Combination of Ruscus aculeatus L. and Vitis vinifera L. Extracts, Magnolol and Diosmetin to Address Chronic Venous Diseases through an Anti-Inflammatory Effect and AP-1 Modulation.

Nocera R et al (2023).
Plants (Basel).
PubMed:
36903912

The Role of Food Supplementation in Microcirculation-A Comprehensive Review.

Review
Raposo A et al (2021).
Biology (Basel).
PubMed:
34356471

Phenolic Compounds and Bioactive Properties of Ruscus aculeatus L. (Asparagaceae): The Pharmacological Potential of an Underexploited Subshrub.

Rodrigues JPB et al (2021).
Molecules.
PubMed:
33810432

Synthesis of alginate-silica hybrid hydrogel for biocatalytic conversion by β-glucosidase in microreactor.

Onbas R and Yesil-Celiktas O (2018).
Eng Life Sci.
PubMed:
32624954

Making the best of the worst of times: traits underlying combined shade and drought tolerance of Ruscus aculeatus and Ruscus microglossum (Asparagaceae).

Pivovaroff A et al (2013).
Funct Plant Biol.
PubMed:
32480962

Antiproliferative and pro-apoptotic activities of wild asparagus (Asparagus acutifolius L.), black bryony (Tamus communis L.) and butcher's broom (Ruscus aculeatus L.) aqueous extracts against T24 and A549 cancer cell lines.

Bilušić T et al (2019).
J Food Biochem.
PubMed:
31353591

Bone protective effects of purified extract from Ruscus aculeatus on ovariectomy-induced osteoporosis in rats.

Chakuleska L et al (2019).
Food Chem Toxicol.
PubMed:
31299293

Biotechnological production of ruscogenins in plant cell and organ cultures of Ruscus aculeatus.

Khojasteh A et al (2019).
Plant Physiol Biochem.
PubMed:
31163340

Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency.

Review Immunology
Lichota A, Gwozdzinski L and Gwozdzinski K (2019).
Eur J Med Chem.
PubMed:
31096120

A Novel Fluoroimmunoassay for Detecting Ruscogenin with Monoclonal Antibodies Conjugated with CdSe/ZnS Quantum Dots.

Zhang H et al (2017).
Molecules.
PubMed:
28933731

Ruscus Genus: A Rich Source of Bioactive Steroidal Saponins.

Masullo M, Pizza C and Piacente S (2016).
Planta Med.
PubMed:
27825178

Biomolecular proteomics discloses ATP synthase as the main target of the natural glycoside deglucoruscin.

Del Gaudio F et al (2016).
Mol Biosyst.
PubMed:
27476482

Combination of Ruscus aculeatus extract, hesperidin methyl chalcone and ascorbic acid: a comprehensive review of their pharmacological and clinical effects and of the pathophysiology of chronic venous disease.

Review
Allaert FA et al (2016).
Int Angiol.
PubMed:
26928296

Ex situ conservation of Ruscus aculeatus L. - ruscogenin biosynthesis, genome-size stability and propagation traits of tissue-cultured clones.

Ivanova T et al (2015).
Biotechnol Biotechnol Equip.
PubMed:
26019616

Ruscus aculeatus (butcher's broom). Monograph.

Review
(2001).
Altern Med Rev.
PubMed:
11804550

Hemorrhoids and varicose veins: a review of treatment options.

Review
MacKay D et al (2001).
Altern Med Rev.
PubMed:
11302778

Effect of temperature on the responsiveness of cutaneous veins to the extract of Ruscus aculeatus.

Rubanyi G, Marcelon G and Vanhoutte PM (1984).
Gen Pharmacol.
PubMed:
6150876