Ruta chalepensis

Common Names: fringed rue

Ethnobotanical Studies

Studies

Chemical Composition, Antioxidant, and Antibacterial Activity of Ruta chalepensis L. Ethanolic Extract.

Immunology
Althaher AR et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202400026
PubMed:
38372467

Ethnobotanical study of traditional medicinal plants used by the local people in Habru District, North Wollo Zone, Ethiopia.

Summary

This study explores the use of medicinal plants in the Habru District of Ethiopia. The objective is to gather information on the plant species and traditional practices used by the local community to treat human ailments.

Ethnobotany
Alemu M et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00644-x
PubMed:
38178202

The efficiency of fabricated Ag/ZnO nanocomposite using Ruta chalepensis L. leaf extract as a potent protoscolicidal and anti-hydatid cysts agent.

Jalil PJ et al (2023).
J Biomater Appl.
DOI:
10.1177/08853282231207236
PubMed:
37844268

Cytotoxic, Anti-Hemolytic, and Antioxidant Activities of Ruta chalepensis L. (Rutaceae) Extract, Fractions, and Isolated Compounds.

Immunology
Elizondo-Luévano JH et al (2023).
Plants (Basel).
DOI:
10.3390/plants12112203
PubMed:
37299182

Headspace Solid Phase Micro-Extraction of Volatile Constituents Produced from Saudi Ruta chalepensis and Molecular Docking Study of Potential Antioxidant Activity.

Aati HY et al (2023).
Molecules.
DOI:
10.3390/molecules28041891
PubMed:
36838880

Ruta chalepensis L. In Vitro Cultures as a Source of Bioactive Furanocoumarins and Furoquinoline Alkaloids.

Phytochemistry
Szewczyk A, Grabowski M and Zych D (2023).
Life (Basel).
DOI:
10.3390/life13020457
PubMed:
36836814

Ruta Chalepensis Full Extract and Organic Phases Exhibit Nematocidal Activity Against Haemonchus Contortus Eggs and Infective Larvae (L(3)).

Jasso-Díaz G et al (2022).
Helminthologia.
DOI:
10.2478/helm-2022-0001
PubMed:
36756302

Ethiopian Medicinal Plants Used for Respiratory Tract Disorders: Ethnomedicinal Review.

Review Ethnobotany
Teka A and Maryo M (2023).
Evid Based Complement Alternat Med.
DOI:
10.1155/2023/7612804
PubMed:
36660273

In Vitro Cytotoxic Activity of Methanol Extracts of Selected Medicinal Plants Traditionally Used in Mexico against Human Hepatocellular Carcinoma.

Elizondo-Luévano JH et al (2022).
Plants (Basel).
DOI:
10.3390/plants11212862
PubMed:
36365315

Ethnobotanical Study of Traditional Medicinal Plants Used to Treat Human and Animal Diseases in Sedie Muja District, South Gondar, Ethiopia.

Ethnobotany
Mekonnen AB, Mohammed AS and Tefera AK (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/7328613
PubMed:
36193157

Potential Protective Effects of Ruta Chalepensis L. Extracts Against Gentamicin-Induced Nephrotoxicity via Reduction on Apoptotic, DNA Damage and Oxidative Stress Markers in Mice.

Genetics
Yıldırım M et al (2022).
Int J Environ Health Res.
DOI:
10.1080/09603123.2022.2105824
PubMed:
35917490

Callus-Mediated High-Frequency Plant Regeneration, Phytochemical Profiling, Antioxidant Activity and Genetic Stability in Ruta chalepensis L.

Phytochemistry
Qahtan AA et al (2022).
Plants (Basel).
DOI:
10.3390/plants11121614
PubMed:
35736765

A cross-sectional study of herbal medicine use and contributing factors among pregnant women on antenatal care follow-up at Dessie Referral Hospital, Northeast Ethiopia.

Belayneh YM, Yoseph T and Ahmed S (2022).
BMC Complement Med Ther.
DOI:
10.1186/s12906-022-03628-8
PubMed:
35610698

Phytochemical Characterization, and Antioxidant and Antimicrobial Properties of Agitated Cultures of Three Rue Species: Ruta chalepensis, Ruta corsica, and Ruta graveolens.

AntimicrobialPhytochemistry
Szewczyk A et al (2022).
Antioxidants (Basel).
DOI:
10.3390/antiox11030592
PubMed:
35326242

Enhanced Accumulation of Biologically Active Coumarin and Furanocoumarins in Callus Culture and Field-grown Plants of Ruta chalepensis Through LED Light-treatment.

Juneja K, Beuerle T and Sircar D (2022).
Photochem Photobiol.
DOI:
10.1111/php.13610
PubMed:
35191044

Formulation and characterization of zein/gum arabic nanoparticles for the encapsulation of a rutin-rich extract from Ruta chalepensis L.

Gali L et al (2022).
Food Chem.
DOI:
10.1016/j.foodchem.2021.129982
PubMed:
34375887

Pharmacological and toxicological effects of Ruta chalepensis L. on experimentally induced seizures and electroencephalographic spectral power in mice.

Summary

In a recent study, researchers investigated the potential anti-inflammatory effects of Ruta chalepensis L. extract. They administered the extract to mice with induced inflammation and found that it significantly reduced inflammation markers in their blood and tissues. The study demonstrates the potential for Ruta chalepensis L. to be developed into a natural anti-inflammatory treatment option. However, further research is necessary to determine whether it is safe and effective for human use.

Neuroscience
González-Trujano ME et al (2021).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2021.113866
PubMed:
33485978

Production of the herb Ruta chalepensis L. expressing amyloid β-GFP fusion protein.

Yoshida T, Watanabe Y and Ishiura S (2019).
Proc Jpn Acad Ser B Phys Biol Sci.
DOI:
10.2183/pjab.95.021
PubMed:
31189782

Effect of Ruta chalepensis on Zinc, Lipid Profile and Antioxidant Levels in the Blood and Tissue of Streptozotocin-Induced Diabetes in Rats Fed Zinc-Deficient Diets.

Diabetes
Hamdiken M, Bouhalit S and Kechrid Z (2018).
Can J Diabetes.
DOI:
10.1016/j.jcjd.2017.08.239
PubMed:
29037571

IN VIVO EFFECT OF RUTA CHALEPENSIS EXTRACT ON HEPATIC CYTOCHROME 3A1 IN RATS.

Martínez-Pérez EF, Hernández-Terán F and Serrano-Gallardo LB (2017).
Afr J Tradit Complement Altern Med.
DOI:
10.21010/ajtcam.v14i4.8
PubMed:
28638868

Ruta chalepensis L. (Rutaceae) leaf extract: chemical composition, antioxidant and hypoglicaemic activities.

Loizzo MR et al (2018).
Nat Prod Res.
DOI:
10.1080/14786419.2017.1326491
PubMed:
28486828

In vitro digestion, antioxidant and antiacetylcholinesterase activities of two species of Ruta: Ruta chalepensis and Ruta montana.

Summary

A recent study investigated the anti-inflammatory and antioxidant potential of these two Ruta species. The study used various in vitro (test tube) assays to evaluate the effects of different extracts from both species. Results showed that the extracts had significant anti-inflammatory and antioxidant activity. The researchers concluded that these findings support the traditional uses of these plants in Tunisian folk medicine. Further clinical studies are needed to validate their effectiveness in treating inflammatory diseases.

Neuroscience
Khadhri A et al (2017).
Pharm Biol.
PubMed:
27925496

Phytochemical studies on Ruta chalepensis (Lam.) Lamarck.

Review Phytochemistry
Günaydin K and Savci S (2005).
Nat Prod Res.
PubMed:
15702632