Salvia fruticosa

Common Names: Greek oregano, Greek sage, salvia de jardín, three-lobe sage

Ethnobotanical Studies

Studies

Computer-Assisted Discovery of Salvia fruticosa Compounds With Schistosomicidal Activity.

Shoko R and Mandivenga F (2024).
Bioinform Biol Insights.
DOI:
10.1177/11779322241240651
PubMed:
38550337

Extraction Optimization and Qualitative/Quantitative Determination of Bioactive Abietane-Type Diterpenes from Three Salvia Species (Common Sage, Greek Sage and Rosemary) by (1)H-qNMR.

Kallimanis P et al (2024).
Molecules.
DOI:
10.3390/molecules29030625
PubMed:
38338370

Chemical Composition of Salvia fruticosa Mill. Essential Oil and Its Protective Effects on Both Photosynthetic Damage and Oxidative Stress in Conocephalum conicum L. Induced by Environmental Heavy Metal Concentrations.

ImmunologyPhytochemistry
Badalamenti N et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12111990
PubMed:
38001843

Chemical Profiling and Antioxidant and Anti-Amyloid Capacities of Salvia fruticosa Extracts from Greece.

Summary

Scientists found that certain fractions of the medicinal plant SF from Greece have significant antioxidant and anti-neurotoxic effects, indicating its potential as a treatment for Alzheimer's disease. Further study of SF extract partitioning is needed.

Immunology
Ververis A et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183191
PubMed:
37765357

Chemical Characterization and Antioxidant, Antibacterial, Antiacetylcholinesterase and Antiproliferation Properties of Salvia fruticosa Miller Extracts.

Summary

Researchers examined the phytochemical composition and biological activities of extracts from . Four solvents of varying polarity were used for extraction, and the extracts were tested for their chemical composition, antioxidant, anti-Alzheimer, and antibacterial properties. The MeOH extract had strong antioxidant and antibacterial activity, while the EtOAc extract had strong anti-Alzheimer and anti-cancer activity. Ten previously unidentified chemical compounds were also discovered. This study highlights the potential of for therapeutic applications.

ImmunologyNeuroscience
Dawra M et al (2023).
Molecules.
DOI:
10.3390/molecules28062429
PubMed:
36985401

Oral Supplementation with Hydroxytyrosol Synthesized Using Genetically Modified Escherichia coli Strains and Essential Oils Mixture: A Pilot Study on the Safety and Biological Activity.

Simos YV et al (2023).
Microorganisms.
DOI:
10.3390/microorganisms11030770
PubMed:
36985343

Modeling and Optimization of Phenolic Compounds from Sage (Salvia fruticosa L.) Post-Distillation Residues: Ultrasound- versus Microwave-Assisted Extraction.

Phytochemistry
Irakli M et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12030549
PubMed:
36978797

In vitro and in silico cholinesterase inhibitory and antioxidant effects of essential oils and extracts of two new Salvia fruticosa mill. cultivars (Turgut and Uysal) and GC-MS analysis of the essential oils.

GastroenterologyPhytochemistry
Abacı N et al (2023).
Int J Environ Health Res.
DOI:
10.1080/09603123.2022.2163988
PubMed:
36739545

Monoterpene synthases of three closely related sage species (Salvia officinalis, S. fruticosa and S. pomifera, Lamiaceae).

Phytochemistry
Schmiderer C, Steinborn R and Novak J (2023).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2023.01.034
PubMed:
36738511

GC-MS and LC-DAD-MS Phytochemical Profiling for Characterization of Three Native Salvia Taxa from Eastern Mediterranean with Antiglycation Properties.

Phytochemistry
Gkioni MD et al (2022).
Molecules.
DOI:
10.3390/molecules28010093
PubMed:
36615289

Influence of Climate-Related Environmental Stresses on Economically Important Essential Oils of Mediterranean Salvia sp.

Review Phytochemistry
Karalija E et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.864807
PubMed:
35599878

Constituents, Antibacterial Adhesion, Cytotoxic and in Vitro Metastasis Blocking Properties of Salvia fruticosa Essential Oils from Three Palestinian Localities.

CancerPhytochemistry
Jaradat N et al (2022).
Chem Biodivers.
DOI:
10.1002/cbdv.202100872
PubMed:
35167185

Chemical and Biological Characterization of the Anticancer Potency of Salvia fruticosa in a Model of Human Malignant Melanoma.

Cancer
Kyriakou S et al (2021).
Plants (Basel).
DOI:
10.3390/plants10112472
PubMed:
34834834

Antischistosomal Activity of Origanum majorana, Ziziphus spina-christi, and Salvia fruticosa Plant Extracts on Hamster Infected with Schistosoma haematobium.

Fadladdin YAJ et al (2021).
Biomed Res Int.
DOI:
10.1155/2021/5545331
PubMed:
34235218

In vitro biological activity of Salvia fruticosa Mill. infusion against amyloid β-peptide-induced toxicity and inhibition of GSK-3β, CK-1δ, and BACE-1 enzymes relevant to Alzheimer's disease.

Summary

Turkish sage, a species traditionally used to improve cognition, has anticholinergic effects and is a potential natural treatment for Alzheimer's disease. This study aimed to understand the mechanism behind its neuroprotective effects and investigate the inhibitory effects of its major compound, rosmarinic acid, on enzymes related to Alzheimer's disease. Results showed that the infusion significantly decreased amyloid beta-induced cytotoxicity and exhibited promising inhibitory activity against key enzymes. The study provides proof of the infusion's potential as a natural treatment for Alzheimer's disease.

Neuroscience
Gürbüz P et al (2021).
Saudi Pharm J.
DOI:
10.1016/j.jsps.2021.01.007
PubMed:
33981172

Ecological and Plant Community Implication on Essential Oils Composition in Useful Wild Officinal Species: A Pilot Case Study in Apulia (Italy).

Phytochemistry
Perrino EV et al (2021).
Plants (Basel).
DOI:
10.3390/plants10030574
PubMed:
33803659

The Therapeutic Potential of the Essential Oil of Thymbra capitata (L.) Cav., Origanum dictamnus L. and Salvia fruticosa Mill. And a Case of Plant-Based Pharmaceutical Development.

Review Phytochemistry
Pirintsos SA et al (2020).
Front Pharmacol.
DOI:
10.3389/fphar.2020.522213
PubMed:
33390932

Morphological, genetic and epigenetic aspects of homoploid hybridization between Salvia officinalis L. and Salvia fruticosa Mill.

Radosavljević I et al (2019).
Sci Rep.
DOI:
10.1038/s41598-019-40080-0
PubMed:
30824783

Salvia fruticosa Induces Vasorelaxation In Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway.

Anwar MA et al (2017).
Sci Rep.
DOI:
10.1038/s41598-017-00790-9
PubMed:
28386068

Salvia fruticosa reduces intrinsic cellular and H2O2-induced DNA oxidation in HEK 293 cells; assessment using flow cytometry.

Genetics
Hani SB and Bayachou M (2014).
Asian Pac J Trop Biomed.
DOI:
10.12980/APJTB.4.2014C1270
PubMed:
25182726

Salvia fruticosa, Salvia officinalis, and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway.

Xavier CP et al (2009).
Nutr Cancer.
DOI:
10.1080/01635580802710733
PubMed:
19838929